(7 nodes) Lateral sprouting from an epithelium network (Capra hircus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

co-expression

protein homology

Your Input:
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
	CELSR1	Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2710 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	AR	Androgen receptor. (891 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
	TP63	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (681 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	FGF10	ENSCHIP00000023678	ENSCHIP00000010028	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.887
BMP4	NOG	ENSCHIP00000023678	ENSCHIP00000005264	Bone morphogenetic protein 4.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.999
BMP4	WNT5A	ENSCHIP00000023678	ENSCHIP00000015533	Bone morphogenetic protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.731
CELSR1	WNT5A	ENSCHIP00000018726	ENSCHIP00000015533	Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.498
FGF10	BMP4	ENSCHIP00000010028	ENSCHIP00000023678	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Bone morphogenetic protein 4.	0.887
FGF10	NOG	ENSCHIP00000010028	ENSCHIP00000005264	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.900
FGF10	WNT5A	ENSCHIP00000010028	ENSCHIP00000015533	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.584
NOG	BMP4	ENSCHIP00000005264	ENSCHIP00000023678	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	Bone morphogenetic protein 4.	0.999
NOG	FGF10	ENSCHIP00000005264	ENSCHIP00000010028	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.900
WNT5A	BMP4	ENSCHIP00000015533	ENSCHIP00000023678	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Bone morphogenetic protein 4.	0.731
WNT5A	CELSR1	ENSCHIP00000015533	ENSCHIP00000018726	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family.	0.498
WNT5A	FGF10	ENSCHIP00000015533	ENSCHIP00000010028	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.584