(6 nodes) Sinoatrial node cell differentiation network (Capra hircus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ISL1	ISL LIM homeobox 1. (349 aa)
	BVES	Blood vessel epicardial substance. (360 aa)
	MESP1	Mesoderm posterior bHLH transcription factor 1. (256 aa)
	TBX18	T-box transcription factor 18. (612 aa)
	TBX3	T-box transcription factor 3. (749 aa)
	SHOX2	Short stature homeobox 2. (319 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ISL1	MESP1	ENSCHIP00000025978	ENSCHIP00000003890	ISL LIM homeobox 1.	Mesoderm posterior bHLH transcription factor 1.	0.501
ISL1	SHOX2	ENSCHIP00000025978	ENSCHIP00000015506	ISL LIM homeobox 1.	Short stature homeobox 2.	0.523
ISL1	TBX18	ENSCHIP00000025978	ENSCHIP00000009044	ISL LIM homeobox 1.	T-box transcription factor 18.	0.758
ISL1	TBX3	ENSCHIP00000025978	ENSCHIP00000009495	ISL LIM homeobox 1.	T-box transcription factor 3.	0.700
MESP1	ISL1	ENSCHIP00000003890	ENSCHIP00000025978	Mesoderm posterior bHLH transcription factor 1.	ISL LIM homeobox 1.	0.501
SHOX2	ISL1	ENSCHIP00000015506	ENSCHIP00000025978	Short stature homeobox 2.	ISL LIM homeobox 1.	0.523
SHOX2	TBX18	ENSCHIP00000015506	ENSCHIP00000009044	Short stature homeobox 2.	T-box transcription factor 18.	0.850
SHOX2	TBX3	ENSCHIP00000015506	ENSCHIP00000009495	Short stature homeobox 2.	T-box transcription factor 3.	0.784
TBX18	ISL1	ENSCHIP00000009044	ENSCHIP00000025978	T-box transcription factor 18.	ISL LIM homeobox 1.	0.758
TBX18	SHOX2	ENSCHIP00000009044	ENSCHIP00000015506	T-box transcription factor 18.	Short stature homeobox 2.	0.850
TBX3	ISL1	ENSCHIP00000009495	ENSCHIP00000025978	T-box transcription factor 3.	ISL LIM homeobox 1.	0.700
TBX3	SHOX2	ENSCHIP00000009495	ENSCHIP00000015506	T-box transcription factor 3.	Short stature homeobox 2.	0.784