25 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BMP4	Bone morphogenetic protein 4. (409 aa)
	ZBTB16	Uncharacterized protein. (673 aa)
	SMAD1	Mothers against decapentaplegic homolog. (465 aa)
	CCN1	Cellular communication network factor 1. (382 aa)
	SOX5	SRY-box transcription factor 5. (787 aa)
	BMP10	Bone morphogenetic protein 10. (424 aa)
	BMP1	Metalloendopeptidase. (988 aa)
	SOX6	SRY-box transcription factor 6. (858 aa)
	SOX9	SRY-box transcription factor 9. (525 aa)
	PKDCC	Protein kinase domain containing, cytoplasmic. (493 aa)
	FGF18	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	GDF5	Growth differentiation factor 5. (499 aa)
	BMP2	TGF_BETA_2 domain-containing protein. (381 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	GLI3	GLI family zinc finger 3. (1614 aa)
	LOXL2	Lysyl oxidase like 2. (791 aa)
	RUNX2	RUNX family transcription factor 2. (585 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
	ZNF219	Zinc finger protein 219. (734 aa)
	BMPR1B	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (558 aa)
	GDF2	Growth differentiation factor 2. (430 aa)
	SMAD7	Mothers against decapentaplegic homolog. (427 aa)
	GDF6	Growth differentiation factor 6. (463 aa)
	HOXA11	Homeobox A11. (317 aa)
	MUSTN1	Uncharacterized protein. (86 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP1	BMP2	ENSCHIP00000027161	ENSCHIP00000010414	Metalloendopeptidase.	TGF_BETA_2 domain-containing protein.	0.507
BMP1	BMP4	ENSCHIP00000027161	ENSCHIP00000023678	Metalloendopeptidase.	Bone morphogenetic protein 4.	0.674
BMP1	LOXL2	ENSCHIP00000027161	ENSCHIP00000014279	Metalloendopeptidase.	Lysyl oxidase like 2.	0.491
BMP10	BMP4	ENSCHIP00000031863	ENSCHIP00000023678	Bone morphogenetic protein 10.	Bone morphogenetic protein 4.	0.665
BMP10	BMPR1B	ENSCHIP00000031863	ENSCHIP00000018336	Bone morphogenetic protein 10.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.615
BMP10	GDF2	ENSCHIP00000031863	ENSCHIP00000018864	Bone morphogenetic protein 10.	Growth differentiation factor 2.	0.829
BMP10	SMAD3	ENSCHIP00000031863	ENSCHIP00000011729	Bone morphogenetic protein 10.	Mothers against decapentaplegic homolog.	0.584
BMP2	BMP1	ENSCHIP00000010414	ENSCHIP00000027161	TGF_BETA_2 domain-containing protein.	Metalloendopeptidase.	0.507
BMP2	BMP4	ENSCHIP00000010414	ENSCHIP00000023678	TGF_BETA_2 domain-containing protein.	Bone morphogenetic protein 4.	0.931
BMP2	BMPR1B	ENSCHIP00000010414	ENSCHIP00000018336	TGF_BETA_2 domain-containing protein.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.996
BMP2	FGF18	ENSCHIP00000010414	ENSCHIP00000008198	TGF_BETA_2 domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.599
BMP2	GDF5	ENSCHIP00000010414	ENSCHIP00000009728	TGF_BETA_2 domain-containing protein.	Growth differentiation factor 5.	0.542
BMP2	RUNX2	ENSCHIP00000010414	ENSCHIP00000015454	TGF_BETA_2 domain-containing protein.	RUNX family transcription factor 2.	0.938
BMP2	SMAD1	ENSCHIP00000010414	ENSCHIP00000007984	TGF_BETA_2 domain-containing protein.	Mothers against decapentaplegic homolog.	0.883
BMP2	SMAD3	ENSCHIP00000010414	ENSCHIP00000011729	TGF_BETA_2 domain-containing protein.	Mothers against decapentaplegic homolog.	0.633
BMP2	SMAD7	ENSCHIP00000010414	ENSCHIP00000021001	TGF_BETA_2 domain-containing protein.	Mothers against decapentaplegic homolog.	0.725
BMP2	SOX9	ENSCHIP00000010414	ENSCHIP00000024523	TGF_BETA_2 domain-containing protein.	SRY-box transcription factor 9.	0.719
BMP4	BMP1	ENSCHIP00000023678	ENSCHIP00000027161	Bone morphogenetic protein 4.	Metalloendopeptidase.	0.674
BMP4	BMP10	ENSCHIP00000023678	ENSCHIP00000031863	Bone morphogenetic protein 4.	Bone morphogenetic protein 10.	0.665
BMP4	BMP2	ENSCHIP00000023678	ENSCHIP00000010414	Bone morphogenetic protein 4.	TGF_BETA_2 domain-containing protein.	0.931