STRINGSTRING
RFLNB RFLNB PTHLH PTHLH NOG NOG ADAMTS7 ADAMTS7 GREM1 GREM1 NKX3-2 NKX3-2 CTSK CTSK RARB RARB CCN4 CCN4 GDF5 GDF5 RARA RARA GLI3 GLI3 IHH IHH RFLNA RFLNA PTPN11 PTPN11 ADAMTS12 ADAMTS12 EFEMP1 EFEMP1 BMP4 BMP4 FRZB FRZB SOX9 SOX9 TGFBR1 TGFBR1 RARG RARG LTBP3 LTBP3 SNAI2 SNAI2 CTNNB1 CTNNB1 CHADL CHADL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RFLNBRefilin B. (216 aa)
PTHLHParathyroid hormone-like protein. (177 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
ADAMTS7ADAM metallopeptidase with thrombospondin type 1 motif 7. (1677 aa)
GREM1Gremlin. (184 aa)
NKX3-2NK3 homeobox 2. (330 aa)
CTSKCathepsin K; Belongs to the peptidase C1 family. (330 aa)
RARBRetinoic acid receptor beta. (448 aa)
CCN4Cellular communication network factor 4. (368 aa)
GDF5Growth differentiation factor 5. (499 aa)
RARARetinoic acid receptor alpha. (462 aa)
GLI3GLI family zinc finger 3. (1614 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
RFLNARefilin A. (200 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
ADAMTS12ADAM metallopeptidase with thrombospondin type 1 motif 12. (1605 aa)
EFEMP1EGF containing fibulin extracellular matrix protein 1. (498 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
FRZBFrizzled related protein. (325 aa)
SOX9SRY-box transcription factor 9. (525 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
RARGRetinoic acid receptor gamma. (458 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1294 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
CTNNB1Catenin beta 1. (781 aa)
CHADLChondroadherin like. (738 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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