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| | APP | Amyloid beta precursor protein. (770 aa) |
| | TYSND1 | Trypsin domain containing 1. (568 aa) |
| | LOC108635363 | Ig-like domain-containing protein. (298 aa) |
| | JMJD8 | Jumonji domain containing 8. (344 aa) |
| | ARV1 | ARV1 homolog, fatty acid homeostasis modulator. (282 aa) |
| | SLC45A3 | Solute carrier family 45 member 3. (550 aa) |
| | SIRT4 | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (315 aa) |
| | IRS2 | Insulin receptor substrate 2. (1465 aa) |
| | OGT | O-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa) |
| | SLC7A11 | Solute carrier family 7 member 11. (503 aa) |
| | MID1IP1 | MID1 interacting protein 1. (182 aa) |
| | SEC14L3 | SEC14 like lipid binding 3. (400 aa) |
| | TTC39A | Tetratricopeptide repeat domain 39A. (581 aa) |
| | ABCD2 | ATP binding cassette subfamily D member 2. (741 aa) |
| | SEC14L6 | SEC14 like lipid binding 6. (397 aa) |
| | P2RY6 | Pyrimidinergic receptor P2Y6. (328 aa) |
| | GUCA2A | Guanylate cyclase activator 2A. (109 aa) |
| | MFSD2A | Major facilitator superfamily domain containing 2A. (524 aa) |
| | EPM2AIP1 | EPM2A interacting protein 1. (608 aa) |
| | LHCGR | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (700 aa) |
| | EPHX2 | Epoxide hydrolase 2. (555 aa) |
| | ATP5IF1 | ATP synthase inhibitory factor subunit 1. (109 aa) |
| | GPLD1 | Glycosylphosphatidylinositol specific phospholipase D1. (848 aa) |
| | PTH | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa) |
| | RD3 | Retinal degeneration 3, GUCY2D regulator. (195 aa) |
| | SCAP | SREBF chaperone. (1278 aa) |
| | TREM2 | Triggering receptor expressed on myeloid cells 2. (230 aa) |
| | APOA5 | Apolipoprotein A5. (368 aa) |
| | TREX1 | Three prime repair exonuclease 1. (315 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa) |
| | MLYCD | Malonyl-CoA decarboxylase. (524 aa) |
| | ENSCHIP00000005096 | Uncharacterized protein. (282 aa) |
| | PIBF1 | Progesterone immunomodulatory binding factor 1. (757 aa) |
| | ENSCHIP00000005178 | Uncharacterized protein. (156 aa) |
| | ETFBKMT | Uncharacterized protein. (245 aa) |
| | TIGAR | TP53 induced glycolysis regulatory phosphatase. (270 aa) |
| | SLC4A1 | Anion exchange protein. (978 aa) |
| | NCOR2 | Nuclear receptor corepressor 2. (2479 aa) |
| | NCOR1 | Nuclear receptor corepressor 1. (2447 aa) |
| | DNAJC30 | DnaJ heat shock protein family (Hsp40) member C30. (226 aa) |
| | PPP4R3B | Protein phosphatase 4 regulatory subunit 3B. (820 aa) |
| | CYP27B1 | Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa) |
| | BMP5 | Bone morphogenetic protein 5. (454 aa) |
| | TTC39B | Tetratricopeptide repeat domain 39B. (598 aa) |
| | APPL2 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (662 aa) |
| | BEND3 | BEN domain containing 3. (829 aa) |
| | NCOA2 | Nuclear receptor coactivator. (1473 aa) |
| | GIP | Gastric inhibitory polypeptide. (146 aa) |
| | SIRT1 | Deacetylase sirtuin-type domain-containing protein. (732 aa) |
| | INS | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (105 aa) |
| | FMO1 | Dimethylaniline monooxygenase [N-oxide-forming]. (550 aa) |
| | PDK3 | Protein-serine/threonine kinase. (415 aa) |
| | LOC102173405 | Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa) |
| | FAM3A | Family with sequence similarity 3 member A. (223 aa) |
| | GUCA1A | Uncharacterized protein. (205 aa) |
| | EIF6 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa) |
| | DKK3 | Dickkopf WNT signaling pathway inhibitor 3. (349 aa) |
| | WDTC1 | WD and tetratricopeptide repeats 1. (678 aa) |
| | DDIT4 | DNA damage inducible transcript 4. (229 aa) |
| | LOC102190194 | Uncharacterized protein. (935 aa) |
| | ENSCHIP00000009034 | Uncharacterized protein. (90 aa) |
| | PDK1 | Protein-serine/threonine kinase. (438 aa) |
| | CLCN2 | Chloride channel protein. (905 aa) |
| | SNCA | Alpha-synuclein; Belongs to the synuclein family. (140 aa) |
| | TSPO | Translocator protein. (169 aa) |
| | CYP7A1 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (501 aa) |
| | GNB3 | G protein subunit beta 3. (338 aa) |
| | APOA4 | Apolipoprotein A4. (380 aa) |
| | ENSCHIP00000010160 | Uncharacterized protein. (252 aa) |
| | RANBP2 | RAN binding protein 2. (3077 aa) |
| | ELOVL5 | Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (299 aa) |
| | BMP2 | TGF_BETA_2 domain-containing protein. (381 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (218 aa) |
| | SIK1 | Uncharacterized protein. (778 aa) |
| | ENSCHIP00000010840 | Uncharacterized protein. (85 aa) |
| | NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1193 aa) |
| | PDK4 | Protein-serine/threonine kinase. (407 aa) |
| | LOC102175794 | Uncharacterized protein. (282 aa) |
| | NR1H3 | Uncharacterized protein. (447 aa) |
| | PTPN2 | Tyrosine-protein phosphatase non-receptor type. (417 aa) |
| | ACTN3 | Actinin alpha 3 (gene/pseudogene). (902 aa) |
| | GUCA1B | Guanylate cyclase activator 1B. (201 aa) |
| | PPARD | Peroxisome proliferator activated receptor delta. (441 aa) |
| | PGP | Phosphoglycolate phosphatase; Belongs to the HAD-like hydrolase superfamily. (323 aa) |
| | CD74 | CD74 molecule. (261 aa) |
| | SEC14L2 | Uncharacterized protein. (403 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1365 aa) |
| | FMO5 | Dimethylaniline monooxygenase [N-oxide-forming]. (533 aa) |
| | H6PD | Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (810 aa) |
| | SNAI1 | Snail family transcriptional repressor 1. (264 aa) |
| | ENSCHIP00000012671 | BHLH domain-containing protein. (304 aa) |
| | ZMPSTE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa) |
| | APOC3 | Apolipoprotein C3. (97 aa) |
| | SOD1 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (154 aa) |
| | LPCAT3 | Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (485 aa) |
| | IGFBP4 | IBP4. (258 aa) |
| | MST1 | Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (722 aa) |
| | DDB1 | Damage specific DNA binding protein 1. (1140 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa) |
| | LCMT1 | Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (335 aa) |
| | BAD | BCL2 associated agonist of cell death. (198 aa) |
| | GCK | Phosphotransferase. (465 aa) |
| | HIF1A | Uncharacterized protein. (823 aa) |
| | REST | Uncharacterized protein. (998 aa) |
| | C1QTNF6 | C1q and TNF related 6. (266 aa) |
| | PODN | Podocan. (614 aa) |
| | ZNF692 | Zinc finger protein 692. (511 aa) |
| | PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa) |
| | PMAIP1 | Phorbol-12-myristate-13-acetate-induced protein 1. (54 aa) |
| | ENO1 | Enolase 1. (434 aa) |
| | PPARGC1A | RRM domain-containing protein. (797 aa) |
| | SERPINA12 | Serpin family A member 12; Belongs to the serpin family. (430 aa) |
| | GFI1 | Growth factor independent 1 transcriptional repressor. (420 aa) |
| | APOC2 | Apolipoprotein C2. (103 aa) |
| | TFF3 | Trefoil factor 3. (81 aa) |
| | AVPR1B | Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (423 aa) |
| | PARK2 | Ubiquitin-like domain-containing protein. (293 aa) |
| | PRMT3 | Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (527 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. (166 aa) |
| | APOB | Apolipoprotein B. (4620 aa) |
| | ADORA2B | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (332 aa) |
| | SIRT7 | Sirtuin 7. (405 aa) |
| | HTR2A | 5-hydroxytryptamine receptor 2A. (470 aa) |
| | MIDN | Midnolin. (505 aa) |
| | SLC35B4 | Solute carrier family 35 member B4. (331 aa) |
| | SIRT5 | NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinyl [...] (310 aa) |
| | NCS1 | Neuronal calcium sensor 1. (190 aa) |
| | NUPR1 | Nuclear protein 1, transcriptional regulator. (82 aa) |
| | NR1D1 | Nuclear receptor subfamily 1 group D member 1. (616 aa) |
| | ENSCHIP00000017929 | Uncharacterized protein. (84 aa) |
| | PLEK | Pleckstrin. (356 aa) |
| | ERFE | Erythroferrone. (331 aa) |
| | EP300 | E1A binding protein p300. (2411 aa) |
| | INSIG2 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (245 aa) |
| | ZBTB20 | Zinc finger and BTB domain containing 20. (751 aa) |
| | FOXO1 | Forkhead box O1. (668 aa) |
| | PARP1 | Poly [ADP-ribose] polymerase. (1020 aa) |
| | PRKCE | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (608 aa) |
| | ATPSCKMT | ATP synthase c subunit lysine N-methyltransferase. (222 aa) |
| | VCP | Valosin containing protein; Belongs to the AAA ATPase family. (816 aa) |
| | LPGAT1 | Lysophosphatidylglycerol acyltransferase 1. (370 aa) |
| | HDAC4 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1089 aa) |
| | IGF1 | Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (188 aa) |
| | ENSCHIP00000020611 | Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (291 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (192 aa) |
| | LDLR | Low density lipoprotein receptor. (787 aa) |
| | SLC4A4 | Anion exchange protein. (1125 aa) |
| | GUCA2B | Guanylate cyclase activator 2B. (113 aa) |
| | ENSCHIP00000021464 | Uncharacterized protein. (135 aa) |
| | ACMSD | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (336 aa) |
| | SEC14L5 | SEC14 like lipid binding 5. (714 aa) |
| | ABCD1 | ATP binding cassette subfamily D member 1. (737 aa) |
| | PPTC7 | Protein phosphatase; Belongs to the PP2C family. (308 aa) |
| | GPD1 | Glycerol-3-phosphate dehydrogenase [NAD(+)]. (358 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | TRIB3 | Tribbles pseudokinase 3. (357 aa) |
| | PLIN5 | Perilipin; Belongs to the perilipin family. (456 aa) |
| | C1QTNF12 | C1q and TNF related 12. (292 aa) |
| | ENSCHIP00000022861 | Protein-serine/threonine kinase. (377 aa) |
| | ACACB | Acetyl-CoA carboxylase beta. (2448 aa) |
| | CLN3 | Battenin. (442 aa) |
| | FMO3 | Dimethylaniline monooxygenase [N-oxide-forming]. (547 aa) |
| | MLXIPL | MLX interacting protein like. (854 aa) |
| | FMO2 | Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa) |
| | FOXK1 | Forkhead box K1. (708 aa) |
| | ANXA1 | Annexin. (346 aa) |
| | ENSCHIP00000023383 | RBR-type E3 ubiquitin transferase. (84 aa) |
| | FOXK2 | Forkhead box K2. (658 aa) |
| | NR1H4 | Nuclear receptor subfamily 1 group H member 4. (486 aa) |
| | ABCB11 | ATP binding cassette subfamily B member 11. (1326 aa) |
| | ABCG4 | ATP binding cassette subfamily G member 4. (658 aa) |
| | KAT2A | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa) |
| | ERLIN1 | ER lipid raft associated 1. (346 aa) |
| | LOC102186084 | Uncharacterized protein. (293 aa) |
| | ARL2 | ARL2-SNX15 readthrough (NMD candidate); Belongs to the small GTPase superfamily. Arf family. (184 aa) |
| | ADIPOR1 | Uncharacterized protein. (375 aa) |
| | GCG | Glucagon. (180 aa) |
| | MALRD1 | MAM and LDL receptor class A domain containing 1. (1834 aa) |
| | PROX1 | Prospero homeobox 1. (734 aa) |
| | SOX9 | SRY-box transcription factor 9. (525 aa) |
| | LOC102176524 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1242 aa) |
| | GIT1 | GIT ArfGAP 1. (738 aa) |
| | CLYBL | Citrate lyase beta like. (329 aa) |
| | APOE | Apolipoprotein E. (326 aa) |
| | FABP5 | FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa) |
| | PARK7 | Parkinsonism associated deglycase. (189 aa) |
| | PDK2 | Protein-serine/threonine kinase. (407 aa) |
| | ENSCHIP00000025560 | Ig-like domain-containing protein. (271 aa) |
| | ENSCHIP00000025627 | Uncharacterized protein. (125 aa) |
| | SLC2A6 | Solute carrier family 2 member 6; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (507 aa) |
| | PDZD3 | PDZ domain containing 3. (471 aa) |
| | FIS1 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa) |
| | SLC7A7 | Solute carrier family 7 member 7. (511 aa) |
| | BCKDK | Protein-serine/threonine kinase. (412 aa) |
| | CYP27C1 | Cytochrome P450 family 27 subfamily C member 1; Belongs to the cytochrome P450 family. (372 aa) |
| | GPER1 | G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (363 aa) |
| | P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa) |
| | ZBTB7A | Zinc finger and BTB domain containing 7A. (602 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa) |
| | KAT2B | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (810 aa) |
| | PANK2 | Pantothenate kinase 2. (453 aa) |
| | DGKQ | Diacylglycerol kinase theta. (785 aa) |
| | LOC102175492 | ANK_REP_REGION domain-containing protein. (1589 aa) |
| | ENSCHIP00000026945 | Enolase_C domain-containing protein. (279 aa) |
| | DKKL1 | Dickkopf like acrosomal protein 1. (233 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (495 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) |
| | INSIG1 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (278 aa) |
| | LEPR | Leptin receptor. (1166 aa) |
| | FGFR4 | Fibroblast growth factor receptor. (870 aa) |
| | PRXL2C | Peroxiredoxin like 2C. (228 aa) |
| | SEC14L4 | SEC14 like lipid binding 4. (406 aa) |
| | LACC1 | Uncharacterized protein. (426 aa) |
| | WDR5 | WD repeat domain 5. (334 aa) |
| | DNM1L | Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (707 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (565 aa) |
| | SPHK2 | Sphingosine kinase 2. (653 aa) |
| | DYRK2 | Dual specificity tyrosine phosphorylation regulated kinase 2. (599 aa) |
| | IGFBP3 | Uncharacterized protein. (293 aa) |
| | SNAI2 | Snail family transcriptional repressor 2. (268 aa) |
| | FMO4 | Dimethylaniline monooxygenase [N-oxide-forming]. (550 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) |
| | USP7 | Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1103 aa) |
| | PLA2G3 | Phospholipase A2 group III. (509 aa) |
| | NLN | Neurolysin. (705 aa) |
| | CBFA2T3 | CBFA2/RUNX1 partner transcriptional co-repressor 3. (714 aa) |
| | PID1 | Phosphotyrosine interaction domain containing 1. (217 aa) |
| | SREBF1 | Uncharacterized protein. (68 aa) |
| | ENSCHIP00000030100 | Uncharacterized protein. (367 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa) |
| | KCNMA1 | Potassium calcium-activated channel subfamily M alpha 1. (1131 aa) |
| | ENSCHIP00000030535 | zf-RING_14 domain-containing protein. (149 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (475 aa) |
| | ACADVL | Acyl-CoA dehydrogenase very long chain. (655 aa) |
| | NKX1-1 | NK1 homeobox 1. (375 aa) |
| | NOS1 | Nitric oxide synthase 1. (1468 aa) |
| | C1QTNF3 | C1q domain-containing protein. (319 aa) |
| | RORA | Uncharacterized protein. (527 aa) |
| | SIRT6 | Sirtuin 6. (335 aa) |
| | ENSCHIP00000031771 | C2 domain-containing protein. (204 aa) |
| | ERLIN2 | ER lipid raft associated 2. (338 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | GNMT | Glycine N-methyltransferase. (295 aa) |
| | PPARA | Peroxisome proliferator activated receptor alpha. (470 aa) |
| | STARD4 | StAR related lipid transfer domain containing 4. (224 aa) |
| | SLC27A4 | Solute carrier family 27 member 4. (643 aa) |
| | ENSCHIP00000032619 | ANK_REP_REGION domain-containing protein. (266 aa) |
| | BMP6 | Bone morphogenetic protein 6. (496 aa) |
| | ADIPOQ | C1q domain-containing protein. (283 aa) |
| | ATCAY | ATCAY kinesin light chain interacting caytaxin. (371 aa) |
| | FAM3C | Family with sequence similarity 3 member C. (227 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1843 aa) |
| | C1QTNF1 | C1q and TNF related 1. (279 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | ENSCHIP00000033232 | Uncharacterized protein. (321 aa) |
| | DUSP12 | Uncharacterized protein. (345 aa) |
| | NR1H2 | Nuclear receptor subfamily 1 group H member 2. (457 aa) |
| | CRY1 | Cryptochrome circadian regulator 1. (593 aa) |
| | FLCN | UDENN FLCN/SMCR8-type domain-containing protein. (579 aa) |
| | LONP2 | Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (852 aa) |
