Your Input: | |||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa) | ||||
CHEK2 | Checkpoint kinase 2. (534 aa) | ||||
BCL11B | BAF chromatin remodeling complex subunit BCL11B. (905 aa) | ||||
BCL2L11 | Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (195 aa) | ||||
GLI3 | GLI family zinc finger 3. (1614 aa) | ||||
KIFAP3 | Kinesin associated protein 3. (749 aa) | ||||
BAK1 | BCL2 antagonist/killer 1. (211 aa) | ||||
WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa) | ||||
ADA | Adenosine deaminase. (400 aa) |