STRINGSTRING
SOX9 SOX9 RIPOR2 RIPOR2 ENSCHIP00000003493 ENSCHIP00000003493 NEUROD2 NEUROD2 HYAL2 HYAL2 POLK POLK ENSCHIP00000000025 ENSCHIP00000000025 IMPACT IMPACT CRIP1 CRIP1 TMEM109 TMEM109 GTF2H5 GTF2H5 COPS9 COPS9 FADD FADD TREX1 TREX1 NFKB1 NFKB1 TNKS1BP1 TNKS1BP1 TP53INP1 TP53INP1 TRPM1 TRPM1 KDM1A KDM1A AQP5 AQP5 SCNN1A SCNN1A TANK TANK HSF1 HSF1 OPN4 OPN4 LRRC8D LRRC8D GPR68 GPR68 USP47 USP47 TIMP1 TIMP1 PIEZO2 PIEZO2 POLH POLH BBC3 BBC3 INO80 INO80 BLM BLM MC1R MC1R XPA XPA ENSCHIP00000007178 ENSCHIP00000007178 YBX3 YBX3 PPID PPID SIRT1 SIRT1 ACTR5 ACTR5 EIF2S1 EIF2S1 SLC12A6 SLC12A6 NIPBL NIPBL DHRS12 DHRS12 ENSCHIP00000007999 ENSCHIP00000007999 PKD2L1 PKD2L1 BCL10 BCL10 CASP9 CASP9 LOC102189098 LOC102189098 TGFB1 TGFB1 GNA11 GNA11 PTPRK PTPRK TMEM150C TMEM150C ENSCHIP00000009957 ENSCHIP00000009957 TLK2 TLK2 TNFRSF1A TNFRSF1A XRCC6 XRCC6 ENSCHIP00000010714 ENSCHIP00000010714 FAS FAS YY1 YY1 CASP3 CASP3 RHNO1 RHNO1 TRPV4 TRPV4 KCNK18 KCNK18 ITGB6 ITGB6 CRYAB CRYAB RAD51AP1 RAD51AP1 SFRP1 SFRP1 ZMPSTE24 ZMPSTE24 RAD9A RAD9A WRN WRN DDB1 DDB1 SLC24A4 SLC24A4 AKT2 AKT2 PRKCD PRKCD RAD1 RAD1 C9orf116 C9orf116 BAD BAD NUCKS1 NUCKS1 TMEM161A TMEM161A REST REST PCNA PCNA TLR3 TLR3 RAD9B RAD9B RCSD1 RCSD1 MAP3K20 MAP3K20 GRB2 GRB2 MAPK3 MAPK3 PIK3CA PIK3CA BAK1 BAK1 MMP2 MMP2 TLR8 TLR8 SLC4A11 SLC4A11 ATM ATM METTL3 METTL3 BNIP3 BNIP3 PDE2A PDE2A HYAL3 HYAL3 MMP9 MMP9 CLOCK CLOCK YAP1 YAP1 MAP3K14 MAP3K14 NOC2L NOC2L ENSCHIP00000017311 ENSCHIP00000017311 OPN1SW OPN1SW DHX36 DHX36 MYD88 MYD88 CREBBP CREBBP XPC XPC EP300 EP300 NEDD4 NEDD4 BMF BMF CASP2 CASP2 RHBDD1 RHBDD1 PARP1 PARP1 SPIDR SPIDR BRCC3 BRCC3 MME MME TLR4 TLR4 SCNN1G SCNN1G ANKRD1 ANKRD1 POLD1 POLD1 ENSCHIP00000020042 ENSCHIP00000020042 LOC102188471 LOC102188471 RHO RHO CASP8 CASP8 BAG3 BAG3 STK39 STK39 NOX1 NOX1 ADSS2 ADSS2 N4BP1 N4BP1 BDKRB2 BDKRB2 IRF1 IRF1 INSRR INSRR RDH11 RDH11 ZBTB1 ZBTB1 LRRC8E LRRC8E PKD2 PKD2 ENSCHIP00000022451 ENSCHIP00000022451 SLC2A4 SLC2A4 TNFSF14 TNFSF14 LIG4 LIG4 LOC102190442 LOC102190442 WNK3 WNK3 BABAM2 BABAM2 GPR88 GPR88 ENSCHIP00000001740 ENSCHIP00000001740 TLR7 TLR7 SMPD1 SMPD1 PIK3R1 PIK3R1 F11R F11R CERS1 CERS1 PBK PBK PCK1 PCK1 INTS7 INTS7 COL1A1 COL1A1 ENSCHIP00000023996 ENSCHIP00000023996 BRCA2 BRCA2 SCNN1B SCNN1B DDB2 DDB2 FBXO4 FBXO4 STK11 STK11 WNT11 WNT11 CUL4B CUL4B PIEZO1 PIEZO1 ATR ATR ENSCHIP00000025113 ENSCHIP00000025113 XRCC5 XRCC5 OPN5 OPN5 PLEC PLEC SDE2 SDE2 CHP1 CHP1 RAB11B RAB11B ERCC4 ERCC4 MMP3 MMP3 ARAF ARAF EGR1 EGR1 ZFP36L1 ZFP36L1 RS1 RS1 AURKB AURKB SFRP2 SFRP2 LTBR LTBR RPE65 RPE65 CNN2 CNN2 SLC38A3 SLC38A3 LOC108633275 LOC108633275 PTGS2 PTGS2 CRADD CRADD CRB1 CRB1 CAPN3 CAPN3 HYAL1 HYAL1 MAPK13 MAPK13 CHEK2 CHEK2 CDC25A CDC25A POLD3 POLD3 SLC9A1 SLC9A1 AQP10 AQP10 PTGER4 PTGER4 AQP2 AQP2 NFATC4 NFATC4 HUS1 HUS1 CD40 CD40 MAP3K2 MAP3K2 GNB5 GNB5 RUVBL2 RUVBL2 IL1B IL1B MFAP4 MFAP4 RGR RGR DDX3X DDX3X RP1 RP1 TP53 TP53 GNAT1 GNAT1 CCND2 CCND2 GRM1 GRM1 CHEK1 CHEK1 TRPV1 TRPV1 GADD45A GADD45A EPO EPO ECT2 ECT2 MAP2K4 MAP2K4 ERCC1 ERCC1 ASIC1 ASIC1 KCNK4 KCNK4 MAP3K1 MAP3K1 AQP1 AQP1 BRCA1 BRCA1 RAD51 RAD51 RGS9 RGS9 ENSCHIP00000033232 ENSCHIP00000033232 PALM PALM NET1 NET1 HRAS HRAS MCOLN1 MCOLN1 HVCN1 HVCN1 FIGNL1 FIGNL1 CDKN1A CDKN1A LOC106502849 LOC106502849 GPLD1 GPLD1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SOX9SRY-box transcription factor 9. (525 aa)
RIPOR2Uncharacterized protein. (1052 aa)
ENSCHIP00000003493MPN domain-containing protein. (262 aa)
NEUROD2Neurogenic differentiation factor. (382 aa)
HYAL2Hyaluronidase. (476 aa)
POLKDNA polymerase kappa. (905 aa)
ENSCHIP00000000025Uncharacterized protein. (552 aa)
IMPACTImpact RWD domain protein. (318 aa)
CRIP1LIM zinc-binding domain-containing protein. (77 aa)
TMEM109Transmembrane protein 109. (243 aa)
GTF2H5General transcription factor IIH subunit 5. (85 aa)
COPS9Uncharacterized protein. (57 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (209 aa)
TREX1Three prime repair exonuclease 1. (315 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
TNKS1BP1Tankyrase 1 binding protein 1. (1648 aa)
TP53INP1Tumor protein p53 inducible nuclear protein 1. (240 aa)
TRPM1Transient receptor potential cation channel subfamily M member 1. (1654 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (873 aa)
AQP5Aquaporin 5; Belongs to the MIP/aquaporin (TC 1.A.8) family. (265 aa)
SCNN1ASodium channel epithelial 1 alpha subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (672 aa)
TANKTBD domain-containing protein. (422 aa)
HSF1HSF_DOMAIN domain-containing protein. (537 aa)
OPN4Opsin 4. (493 aa)
LRRC8DLeucine rich repeat containing 8 VRAC subunit D. (858 aa)
GPR68G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (371 aa)
USP47Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1391 aa)
TIMP1NTR domain-containing protein. (207 aa)
PIEZO2Piezo-type mechanosensitive ion channel component. (2736 aa)
POLHDNA polymerase eta. (733 aa)
BBC3Uncharacterized protein. (193 aa)
INO80INO80 complex ATPase subunit. (1566 aa)
BLMBLM RecQ like helicase. (1429 aa)
MC1RMelanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta) and ACTH. Does not seem to be active with gamma-MSH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Could be involved in spermatogenesis. (317 aa)
XPAXPA, DNA damage recognition and repair factor. (273 aa)
ENSCHIP00000007178Uncharacterized protein. (452 aa)
YBX3Y-box binding protein 3. (376 aa)
PPIDUncharacterized protein. (370 aa)
SIRT1Deacetylase sirtuin-type domain-containing protein. (732 aa)
ACTR5Actin related protein 5; Belongs to the actin family. (615 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
SLC12A6Solute carrier family 12 member 6. (1150 aa)
NIPBLNipped-B protein. (2804 aa)
DHRS12Dehydrogenase/reductase 12. (317 aa)
ENSCHIP00000007999Uncharacterized protein. (233 aa)
PKD2L1Polycystin 2 like 1, transient receptor potential cation channel. (757 aa)
BCL10BCL10 immune signaling adaptor. (230 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (452 aa)
LOC102189098MPN domain-containing protein. (291 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
GNA11G protein subunit alpha 11. (361 aa)
PTPRKProtein tyrosine phosphatase receptor type K. (1485 aa)
TMEM150CTransmembrane protein 150C. (249 aa)
ENSCHIP00000009957Calponin-homology (CH) domain-containing protein. (123 aa)
TLK2Tousled like kinase 2. (767 aa)
TNFRSF1ATNF receptor superfamily member 1A. (449 aa)
XRCC6X-ray repair cross complementing 6. (607 aa)
ENSCHIP00000010714Calponin-homology (CH) domain-containing protein. (308 aa)
FASUncharacterized protein. (297 aa)
YY1YY1 transcription factor. (415 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (275 aa)
RHNO1RAD9-HUS1-RAD1 interacting nuclear orphan 1. (241 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
KCNK18Potassium two pore domain channel subfamily K member 18; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (380 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (844 aa)
CRYABCrystallin alpha B; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (175 aa)
RAD51AP1RAD51 associated protein 1. (326 aa)
SFRP1Secreted frizzled related protein 1. (308 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
RAD9ACell cycle checkpoint control protein; Belongs to the rad9 family. (395 aa)
WRNWRN RecQ like helicase. (1405 aa)
DDB1Damage specific DNA binding protein 1. (1140 aa)
SLC24A4Solute carrier family 24 member 4; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (603 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (674 aa)
RAD1Uncharacterized protein. (279 aa)
C9orf116Chromosome 9 open reading frame 116. (136 aa)
BADBCL2 associated agonist of cell death. (198 aa)
NUCKS1Uncharacterized protein. (248 aa)
TMEM161ATransmembrane protein 161A. (495 aa)
RESTUncharacterized protein. (998 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (918 aa)
RAD9BCell cycle checkpoint control protein; Belongs to the rad9 family. (428 aa)
RCSD1RCSD domain containing 1. (385 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (800 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
MMP2Matrix metallopeptidase 2. (661 aa)
TLR8TIR domain-containing protein; Belongs to the Toll-like receptor family. (1085 aa)
SLC4A11Solute carrier family 4 member 11. (855 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3058 aa)
METTL3Methyltransferase like 3; Belongs to the MT-A70-like family. (579 aa)
BNIP3BCL2 interacting protein 3. (193 aa)
PDE2APhosphodiesterase. (821 aa)
HYAL3Hyaluronidase. (419 aa)
MMP9Uncharacterized protein. (709 aa)
CLOCKClock circadian regulator. (845 aa)
YAP1Yes associated protein 1. (503 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (953 aa)
NOC2LNOC2 like nucleolar associated transcriptional repressor. (746 aa)
ENSCHIP00000017311Protein kinase domain-containing protein. (274 aa)
OPN1SWOpsin 1, short wave sensitive. (349 aa)
DHX36DEAH-box helicase 36. (1010 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
CREBBPCREB binding protein. (2435 aa)
XPCXPC complex subunit, DNA damage recognition and repair factor. (877 aa)
EP300E1A binding protein p300. (2411 aa)
NEDD4E3 ubiquitin-protein ligase. (836 aa)
BMFBcl2 modifying factor. (184 aa)
CASP2Caspase 2; Belongs to the peptidase C14A family. (456 aa)
RHBDD1Rhomboid domain containing 1. (322 aa)
PARP1Poly [ADP-ribose] polymerase. (1020 aa)
SPIDRScaffold protein involved in DNA repair. (916 aa)
BRCC3MPN domain-containing protein. (288 aa)
MMEMembrane metalloendopeptidase. (775 aa)
TLR4TIR domain-containing protein; Belongs to the Toll-like receptor family. (841 aa)
SCNN1GSodium channel epithelial 1 gamma subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (652 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
POLD1DNA polymerase. (1115 aa)
ENSCHIP00000020042MPN domain-containing protein. (245 aa)
LOC102188471Uncharacterized protein. (57 aa)
RHORhodopsin. (348 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (488 aa)
BAG3BCL2 associated athanogene 3. (576 aa)
STK39Serine/threonine kinase 39. (631 aa)
NOX1NADPH oxidase 1. (498 aa)
ADSS2Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (456 aa)
N4BP1NEDD4 binding protein 1. (897 aa)
BDKRB2Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (387 aa)
IRF1Interferon regulatory factor. (322 aa)
INSRRTyrosine-protein kinase receptor. (1301 aa)
RDH11Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (329 aa)
ZBTB1Zinc finger and BTB domain containing 1. (644 aa)
LRRC8ELeucine rich repeat containing 8 VRAC subunit E. (791 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (978 aa)
ENSCHIP00000022451TBD domain-containing protein. (430 aa)
SLC2A4MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
TNFSF14TNF_2 domain-containing protein. (237 aa)
LIG4DNA ligase. (911 aa)
LOC102190442Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (270 aa)
WNK3WNK lysine deficient protein kinase 3. (1790 aa)
BABAM2BRISC and BRCA1 A complex member 2. (383 aa)
GPR88G protein-coupled receptor 88. (383 aa)
ENSCHIP00000001740Uncharacterized protein. (101 aa)
TLR7TIR domain-containing protein. (1054 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (619 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
F11RF11 receptor. (298 aa)
CERS1TLC domain-containing protein. (333 aa)
PBKProtein kinase domain-containing protein. (325 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
INTS7Integrator complex subunit 7. (962 aa)
COL1A1Collagen type I alpha 1 chain. (1463 aa)
ENSCHIP00000023996PPIase cyclophilin-type domain-containing protein. (317 aa)
BRCA2BRCA2 DNA repair associated. (3405 aa)
SCNN1BSodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (774 aa)
DDB2Damage specific DNA binding protein 2. (411 aa)
FBXO4F-box protein 4. (393 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (442 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
CUL4BCullin 4B; Belongs to the cullin family. (1027 aa)
PIEZO1Piezo-type mechanosensitive ion channel component. (2512 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa)
ENSCHIP00000025113PAS domain-containing protein. (954 aa)
XRCC5X-ray repair cross complementing 5. (736 aa)
OPN5Opsin 5; Belongs to the G-protein coupled receptor 1 family. (353 aa)
PLECPlectin. (4150 aa)
SDE2SDE2 telomere maintenance homolog. (453 aa)
CHP1Calcineurin like EF-hand protein 1. (195 aa)
RAB11BUncharacterized protein. (224 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (916 aa)
MMP3Matrix metallopeptidase 3. (477 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (611 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa)
ZFP36L1ZFP36 ring finger protein like 1. (338 aa)
RS1Retinoschisin 1. (224 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (344 aa)
SFRP2Secreted frizzled related protein 2. (294 aa)
LTBRUncharacterized protein. (428 aa)
RPE65Retinoid isomerohydrolase RPE65. (533 aa)
CNN2Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (309 aa)
SLC38A3Solute carrier family 38 member 3. (509 aa)
LOC108633275TNF_2 domain-containing protein. (230 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
CRADDCASP2 and RIPK1 domain containing adaptor with death domain. (199 aa)
CRB1Crumbs cell polarity complex component 1. (1409 aa)
CAPN3Calpain 3; Belongs to the peptidase C2 family. (819 aa)
HYAL1Hyaluronidase. (450 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
CHEK2Checkpoint kinase 2. (534 aa)
CDC25ACell division cycle 25A. (517 aa)
POLD3Uncharacterized protein. (464 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (818 aa)
AQP10Aquaporin 10; Belongs to the MIP/aquaporin (TC 1.A.8) family. (285 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (513 aa)
AQP2Aquaporin 2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
NFATC4Nuclear factor of activated T cells 4. (901 aa)
HUS1Checkpoint protein; Belongs to the HUS1 family. (280 aa)
CD40CD40 molecule. (280 aa)
MAP3K2Mitogen-activated protein kinase kinase kinase 2. (619 aa)
GNB5G protein subunit beta 5. (402 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (471 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa)
MFAP4Microfibril associated protein 4. (255 aa)
RGRRetinal G protein coupled receptor; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. (291 aa)
DDX3XUncharacterized protein; Belongs to the DEAD box helicase family. (661 aa)
RP1RP1 axonemal microtubule associated. (2115 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa)
GNAT1G protein subunit alpha transducin 1. (350 aa)
CCND2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (292 aa)
GRM1Glutamate metabotropic receptor 1. (1192 aa)
CHEK1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (476 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (842 aa)
GADD45AGrowth arrest and DNA damage inducible alpha. (165 aa)
EPOErythropoietin. (208 aa)
ECT2Epithelial cell transforming 2. (913 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (412 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (294 aa)
ASIC1Acid sensing ion channel subunit 1; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (526 aa)
KCNK4Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (408 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1507 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1843 aa)
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
RGS9Regulator of G protein signaling 9. (608 aa)
ENSCHIP00000033232Uncharacterized protein. (321 aa)
PALMParalemmin. (382 aa)
NET1Neuroepithelial cell transforming 1. (592 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
MCOLN1Mucolipin 1. (580 aa)
HVCN1Hydrogen voltage gated channel 1. (275 aa)
FIGNL1Fidgetin like 1; Belongs to the AAA ATPase family. (677 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (161 aa)
LOC106502849Uncharacterized protein. (242 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (848 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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