STRINGSTRING
LOC108634920 LOC108634920 ANKRD1 ANKRD1 ENSCHIP00000020157 ENSCHIP00000020157 KCNH2 KCNH2 ENSCHIP00000020652 ENSCHIP00000020652 LOC102188304 LOC102188304 E2F1 E2F1 ENSCHIP00000015235 ENSCHIP00000015235 MEF2C MEF2C N6AMT1 N6AMT1 LOC108633308 LOC108633308 CYP26A1 CYP26A1 GSTA4 GSTA4 CYP26B1 CYP26B1 CRYZ CRYZ HNF4A HNF4A LOC102177333 LOC102177333 FMO1 FMO1 LOC102173405 LOC102173405 LOC102185708 LOC102185708 NR1I2 NR1I2 FMO4 FMO4 IL1B IL1B AHR AHR LOC102185739 LOC102185739 PDE4A PDE4A LOC102188176 LOC102188176 WNK4 WNK4 FMO3 FMO3 KCNQ1 KCNQ1 FMO2 FMO2 ABCB11 ABCB11 CERS1 CERS1 LOC102177329 LOC102177329 LOC102190840 LOC102190840 CYP2S1 CYP2S1 ENSCHIP00000026019 ENSCHIP00000026019 LOC102191099 LOC102191099 LOC102190288 LOC102190288 NOS2 NOS2 PON2 PON2 SULT1C3 SULT1C3 ACER2 ACER2 TP53 TP53 AIP AIP CYP1A1 CYP1A1 RORA RORA CYP2U1 CYP2U1 NFE2L2 NFE2L2 LOC102174170 LOC102174170 CYP46A1 CYP46A1 LOC102180880 LOC102180880 LOC108633257 LOC108633257 ADIPOQ ADIPOQ ENSCHIP00000032824 ENSCHIP00000032824 ENSCHIP00000027669 ENSCHIP00000027669 CMBL CMBL NUDT15 NUDT15 NCEH1 NCEH1 LOC100861186 LOC100861186 GAS6 GAS6 RBM22 RBM22 CYP2R1 CYP2R1 LOC102169851 LOC102169851 PRKAA2 PRKAA2 FMO5 FMO5 VKORC1 VKORC1 AS3MT AS3MT LOC106503891 LOC106503891 LOC102171556 LOC102171556 LOC102189985 LOC102189985 AOX1 AOX1 ENSCHIP00000010950 ENSCHIP00000010950 PPM1E PPM1E DPEP1 DPEP1 CYP1A2 CYP1A2 LOC102185056 LOC102185056 LOC102169002 LOC102169002 S100A12 S100A12 CYP1B1 CYP1B1 LPO LPO LOC102178311 LOC102178311 LOC102186455 LOC102186455 ACAA1 ACAA1 NKX3-1 NKX3-1 RECQL5 RECQL5 GSTM3 GSTM3 LOC102184867 LOC102184867 HTR1B HTR1B AHRR AHRR LOC102173702 LOC102173702 LOC102174708 LOC102174708 GPLD1 GPLD1 PPP1R12A PPP1R12A LOC102172669 LOC102172669 PDE4B PDE4B LOC102174448 LOC102174448 CYP2W1 CYP2W1 CRKL CRKL KCNE2 KCNE2 LOC102174444 LOC102174444 ENSCHIP00000002550 ENSCHIP00000002550 TPMT TPMT LOC108633281 LOC108633281 SULT1B1 SULT1B1 RB1 RB1 GSTO2 GSTO2 ENSCHIP00000001324 ENSCHIP00000001324 LOC102168381 LOC102168381 LOC102180722 LOC102180722 CYP2E1 CYP2E1 LOC102179192 LOC102179192 PPM1F PPM1F LOC108634669 LOC108634669 ENSCHIP00000033232 ENSCHIP00000033232 TFRC TFRC MCM7 MCM7 PCNA PCNA REST REST BRAF BRAF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC108634920Uncharacterized protein; Belongs to the cytochrome P450 family. (332 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
ENSCHIP00000020157Uncharacterized protein; Belongs to the cytochrome P450 family. (262 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2. (1145 aa)
ENSCHIP00000020652Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (262 aa)
LOC102188304Uncharacterized protein; Belongs to the cytochrome P450 family. (490 aa)
E2F1E2F transcription factor 1. (441 aa)
ENSCHIP00000015235Uncharacterized protein. (120 aa)
MEF2CMADS-box domain-containing protein. (441 aa)
N6AMT1N-6 adenine-specific DNA methyltransferase 1. (214 aa)
LOC108633308Uncharacterized protein; Belongs to the cytochrome P450 family. (493 aa)
CYP26A1Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. (497 aa)
GSTA4Glutathione S-transferase alpha 4. (222 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
CRYZCrystallin zeta. (330 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (486 aa)
LOC102177333Uncharacterized protein; Belongs to the cytochrome P450 family. (500 aa)
FMO1Dimethylaniline monooxygenase [N-oxide-forming]. (550 aa)
LOC102173405Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa)
LOC102185708Uncharacterized protein; Belongs to the cytochrome P450 family. (490 aa)
NR1I2Nuclear receptor subfamily 1 group I member 2. (450 aa)
FMO4Dimethylaniline monooxygenase [N-oxide-forming]. (550 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa)
AHRUncharacterized protein. (842 aa)
LOC102185739Uncharacterized protein; Belongs to the cytochrome P450 family. (491 aa)
PDE4APhosphodiesterase. (877 aa)
LOC102188176FAD-binding PCMH-type domain-containing protein. (1339 aa)
WNK4WNK lysine deficient protein kinase 4. (1235 aa)
FMO3Dimethylaniline monooxygenase [N-oxide-forming]. (547 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (670 aa)
FMO2Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa)
ABCB11ATP binding cassette subfamily B member 11. (1326 aa)
CERS1TLC domain-containing protein. (333 aa)
LOC102177329Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
LOC102190840Uncharacterized protein; Belongs to the cytochrome P450 family. (528 aa)
CYP2S1Cytochrome P450 family 2 subfamily S member 1; Belongs to the cytochrome P450 family. (494 aa)
ENSCHIP00000026019Uncharacterized protein. (162 aa)
LOC102191099Uncharacterized protein; Belongs to the cytochrome P450 family. (496 aa)
LOC102190288UDPGT domain-containing protein; Belongs to the UDP-glycosyltransferase family. (554 aa)
NOS2Nitric oxide synthase, inducible; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S- nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in i [...] (1154 aa)
PON2Paraoxonase 2. (367 aa)
SULT1C3Sulfotransferase; Belongs to the sulfotransferase 1 family. (304 aa)
ACER2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa)
AIPPeptidylprolyl isomerase. (330 aa)
CYP1A1Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. (520 aa)
RORAUncharacterized protein. (527 aa)
CYP2U1Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family. (543 aa)
NFE2L2Nuclear factor erythroid 2-related factor 2. (616 aa)
LOC102174170Glutathione S-transferase. (222 aa)
CYP46A1Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. (516 aa)
LOC102180880C-C motif chemokine. (92 aa)
LOC108633257Uncharacterized protein; Belongs to the cytochrome P450 family. (481 aa)
ADIPOQC1q domain-containing protein. (283 aa)
ENSCHIP00000032824Uncharacterized protein. (93 aa)
ENSCHIP00000027669Uncharacterized protein. (462 aa)
CMBLCarboxymethylenebutenolidase homolog. (282 aa)
NUDT15Nudix hydrolase 15. (171 aa)
NCEH1Neutral cholesterol ester hydrolase 1. (408 aa)
LOC100861186Uncharacterized protein; Belongs to the cytochrome P450 family. (492 aa)
GAS6Growth arrest specific 6. (671 aa)
RBM22RNA binding motif protein 22. (420 aa)
CYP2R1Cytochrome P450 family 2 subfamily R member 1; Belongs to the cytochrome P450 family. (501 aa)
LOC102169851Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
FMO5Dimethylaniline monooxygenase [N-oxide-forming]. (533 aa)
VKORC1Vitamin K epoxide reductase complex subunit 1. (163 aa)
AS3MTArsenite methyltransferase. (374 aa)
LOC106503891Uncharacterized protein; Belongs to the cytochrome P450 family. (440 aa)
LOC102171556Uncharacterized protein. (1318 aa)
LOC102189985Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
AOX1Aldehyde oxidase 1. (1339 aa)
ENSCHIP00000010950Uncharacterized protein. (188 aa)
PPM1EProtein phosphatase, Mg2+/Mn2+ dependent 1E. (669 aa)
DPEP1Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (410 aa)
CYP1A2Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. (533 aa)
LOC102185056Uncharacterized protein; Belongs to the cytochrome P450 family. (490 aa)
LOC102169002Uncharacterized protein; Belongs to the cytochrome P450 family. (500 aa)
S100A12Protein S100; Belongs to the S-100 family. (92 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (539 aa)
LPOLactoperoxidase; Antimicrobial agent which utilizes hydrogen peroxide and thiocyanate (SCN) to generate the antimicrobial substance hypothiocyanous acid (HOSCN). May protect the udder from infection and promote growth in newborns. Inhibits growth of several fungi including A.niger, Trichoderma species, C.cassicola, P.meadii and C.salmonicolor. Does not have anti- fungal activity towards C.albicans and Pythium species. Inhibits growth of several Gram-positive bacteria including some Staphylococcus species and Gram-negative bacteria including E.coli, P.aeruginosa and some Salmonella spec [...] (712 aa)
LOC102178311Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (277 aa)
LOC102186455Uncharacterized protein; Belongs to the cytochrome P450 family. (490 aa)
ACAA1Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (424 aa)
NKX3-1NK3 homeobox 1. (239 aa)
RECQL5ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (991 aa)
GSTM3Glutathione S-transferase. (232 aa)
LOC102184867Uncharacterized protein; Belongs to the cytochrome P450 family. (502 aa)
HTR1B5-hydroxytryptamine receptor 1B. (389 aa)
AHRRUncharacterized protein. (698 aa)
LOC102173702Uncharacterized protein. (223 aa)
LOC102174708Uncharacterized protein; Belongs to the GST superfamily. (222 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (848 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1029 aa)
LOC102172669Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (286 aa)
PDE4BPhosphodiesterase. (659 aa)
LOC102174448Dimethylaniline monooxygenase [N-oxide-forming]. (528 aa)
CYP2W1Cytochrome P450 family 2 subfamily W member 1; Belongs to the cytochrome P450 family. (493 aa)
CRKLCRK like proto-oncogene, adaptor protein. (302 aa)
KCNE2Potassium voltage-gated channel subfamily E regulatory subunit 2. (123 aa)
LOC102174444Uncharacterized protein. (222 aa)
ENSCHIP00000002550Uncharacterized protein. (452 aa)
TPMTThiopurine S-methyltransferase. (245 aa)
LOC108633281Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (277 aa)
SULT1B1Sulfotransferase; Belongs to the sulfotransferase 1 family. (296 aa)
RB1RB transcriptional corepressor 1. (931 aa)
GSTO2Glutathione S-transferase omega 2; Belongs to the GST superfamily. (244 aa)
ENSCHIP00000001324Uncharacterized protein. (265 aa)
LOC102168381Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
LOC102180722Uncharacterized protein. (450 aa)
CYP2E1Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. (495 aa)
LOC102179192Uncharacterized protein; Belongs to the cytochrome P450 family. (431 aa)
PPM1FProtein phosphatase, Mg2+/Mn2+ dependent 1F. (418 aa)
LOC108634669Uncharacterized protein; Belongs to the cytochrome P450 family. (500 aa)
ENSCHIP00000033232Uncharacterized protein. (321 aa)
TFRCTransferrin receptor. (790 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
RESTUncharacterized protein. (998 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (774 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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