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| | ENSCHIP00000000025 | Uncharacterized protein. (552 aa) |
| | BMPR1A | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) |
| | ARHGEF5 | DH domain-containing protein. (449 aa) |
| | ADRA2A | Adrenoceptor alpha 2A. (468 aa) |
| | PAK1 | Non-specific serine/threonine protein kinase. (544 aa) |
| | NEK10 | NIMA related kinase 10. (1163 aa) |
| | CDK5R1 | Cyclin-dependent kinase 5 activator. (307 aa) |
| | TCIM | Transcriptional and immune response regulator. (106 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | MLST8 | MTOR associated protein, LST8 homolog. (338 aa) |
| | SLC8A2 | Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (922 aa) |
| | SRC | Tyrosine-protein kinase. (538 aa) |
| | STRADA | Protein kinase domain-containing protein. (433 aa) |
| | TRAF2 | TNF receptor-associated factor. (497 aa) |
| | PDGFD | Platelet derived growth factor D; Belongs to the PDGF/VEGF growth factor family. (370 aa) |
| | DAB2IP | DAB2 interacting protein. (1198 aa) |
| | FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa) |
| | EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa) |
| | DRD4 | Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (357 aa) |
| | SPRY2 | Sprouty RTK signaling antagonist 2. (315 aa) |
| | FZD10 | Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa) |
| | MAP3K12 | Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (892 aa) |
| | SPDYC | Speedy/RINGO cell cycle regulator family member C. (294 aa) |
| | CCNY | Cyclin Y; Belongs to the cyclin family. (341 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (214 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) |
| | MAP3K4 | Mitogen-activated protein kinase kinase kinase 4. (1590 aa) |
| | IQGAP1 | IQ motif containing GTPase activating protein 1. (1657 aa) |
| | RASGRP1 | RAS guanyl releasing protein 1. (773 aa) |
| | MAP3K11 | Mitogen-activated protein kinase kinase kinase. (862 aa) |
| | AXIN1 | Axin 1. (867 aa) |
| | CIB1 | Calcium and integrin binding 1. (191 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa) |
| | NTRK3 | Tyrosine-protein kinase receptor. (825 aa) |
| | SIRT1 | Deacetylase sirtuin-type domain-containing protein. (732 aa) |
| | CCNYL1 | Cyclin Y like 1; Belongs to the cyclin family. (363 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (860 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | PARP16 | Poly [ADP-ribose] polymerase. (324 aa) |
| | EDN1 | Endothelin 1. (202 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (718 aa) |
| | SYK | Spleen associated tyrosine kinase. (636 aa) |
| | SNCA | Alpha-synuclein; Belongs to the synuclein family. (140 aa) |
| | NTF3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (266 aa) |
| | RPS3 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa) |
| | CKS1B | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | CDK5R2 | Cyclin-dependent kinase 5 activator. (373 aa) |
| | TELO2 | Telomere maintenance 2. (825 aa) |
| | SPATC1 | Spermatogenesis and centriole associated 1. (476 aa) |
| | BMP2 | TGF_BETA_2 domain-containing protein. (381 aa) |
| | MTCP1 | Mature T cell proliferation 1. (107 aa) |
| | DVL3 | Dishevelled segment polarity protein 3. (716 aa) |
| | ENSCHIP00000011371 | Uncharacterized protein. (193 aa) |
| | ADAM17 | ADAM metallopeptidase domain 17. (829 aa) |
| | AGER | Advanced glycosylation end-product specific receptor. (416 aa) |
| | HMGA2 | Uncharacterized protein. (104 aa) |
| | RHOA | Ras-like protein family member A. (193 aa) |
| | ENSCHIP00000011995 | Uncharacterized protein. (126 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1365 aa) |
| | SASH1 | SAM and SH3 domain containing 1. (1236 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa) |
| | MAP2K2 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa) |
| | TNFSF11 | Tumor necrosis factor ligand superfamily member. (316 aa) |
| | MAP3K13 | Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (1001 aa) |
| | STRADB | STE20 related adaptor beta. (418 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (573 aa) |
| | ENSCHIP00000015226 | KH type-2 domain-containing protein. (204 aa) |
| | PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (397 aa) |
| | ENSCHIP00000015450 | BRCT domain-containing protein. (152 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa) |
| | PKD1 | Polycystin 1, transient receptor potential channel interacting. (4303 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. (166 aa) |
| | CCNT2 | Cyclin T2; Belongs to the cyclin family. (725 aa) |
| | LTF | Lactotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity. Shows a preferential cleavage at -Arg-Ser-Arg-Arg-|- and -Arg-Arg-Ser-Arg-|-, and of Z-Phe-Arg-|-aminomethylcoumarin sites. (754 aa) |
| | ROBO1 | Uncharacterized protein. (1474 aa) |
| | THBS1 | Thrombospondin 1. (1218 aa) |
| | LOC102175500 | Uncharacterized protein. (295 aa) |
| | BMPR1B | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (558 aa) |
| | TGFA | Transforming growth factor alpha. (215 aa) |
| | CAMK1 | Calcium/calmodulin dependent protein kinase I; Belongs to the protein kinase superfamily. (370 aa) |
| | TPD52L1 | TPD52 like 1. (204 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa) |
| | CCL19 | C-C motif chemokine. (102 aa) |
| | PTPN1 | Tyrosine-protein phosphatase non-receptor type. (424 aa) |
| | TLR4 | TIR domain-containing protein; Belongs to the Toll-like receptor family. (841 aa) |
| | DIPK2A | Divergent protein kinase domain 2A. (430 aa) |
| | RALB | RAS like proto-oncogene B. (206 aa) |
| | ENSCHIP00000020611 | Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (291 aa) |
| | LOC102175356 | Uncharacterized protein. (227 aa) |
| | ADAM8 | ADAM metallopeptidase domain 8. (827 aa) |
| | MAP3K10 | Mitogen-activated protein kinase kinase kinase. (951 aa) |
| | FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1337 aa) |
| | ADAM9 | ADAM metallopeptidase domain 9. (821 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa) |
| | TAOK3 | TAO kinase 3. (930 aa) |
| | IL34 | Interleukin 34. (233 aa) |
| | PKD2 | Polycystin 2, transient receptor potential cation channel. (978 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1208 aa) |
| | DBF4 | DBF4 zinc finger. (675 aa) |
| | CAB39L | Calcium binding protein 39 like. (334 aa) |
| | RPTOR | Regulatory associated protein of MTOR complex 1. (1342 aa) |
| | EPGN | Epithelial mitogen. (136 aa) |
| | IGF2 | Insulin-like growth factor II. (179 aa) |
| | PSRC1 | Proline and serine rich coiled-coil 1. (326 aa) |
| | SYAP1 | Synapse associated protein 1. (358 aa) |
| | PDCD10 | Uncharacterized protein. (212 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (397 aa) |
| | ENSCHIP00000024183 | Uncharacterized protein. (207 aa) |
| | PROX1 | Prospero homeobox 1. (734 aa) |
| | NOX4 | NADPH oxidase 4. (578 aa) |
| | PIK3R5 | Phosphoinositide-3-kinase regulatory subunit 5. (898 aa) |
| | CEMIP | Cell migration inducing hyaluronidase 1. (1348 aa) |
| | LRRK2 | Leucine rich repeat kinase 2. (2527 aa) |
| | LOC102176524 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1242 aa) |
| | MNAT1 | CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa) |
| | ERN2 | Endoplasmic reticulum to nucleus signaling 2. (925 aa) |
| | MAPRE3 | Microtubule associated protein RP/EB family member 3. (281 aa) |
| | CKS2 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | KIT | Mast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] (974 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1067 aa) |
| | P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa) |
| | ACSL1 | Acyl-CoA synthetase long chain family member 1. (719 aa) |
| | ENSCHIP00000026415 | Protein kinase domain-containing protein. (322 aa) |
| | RICTOR | RPTOR independent companion of MTOR complex 2. (1707 aa) |
| | TCL1B | Uncharacterized protein. (126 aa) |
| | SPATC1L | Spermatogenesis and centriole associated 1 like. (343 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (495 aa) |
| | ENSCHIP00000027417 | Uncharacterized protein. (185 aa) |
| | INCENP | Inner centromere protein. (873 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | CCNK | Cyclin K; Belongs to the cyclin family. (600 aa) |
| | MAP4K2 | Mitogen-activated protein kinase kinase kinase kinase 2; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (795 aa) |
| | FERMT2 | Fermitin family member 2. (680 aa) |
| | ALS2 | Alsin Rho guanine nucleotide exchange factor ALS2. (1677 aa) |
| | SPDYA | Speedy/RINGO cell cycle regulator family member A. (312 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1366 aa) |
| | CCNT1 | CYCLIN domain-containing protein; Belongs to the cyclin family. (726 aa) |
| | CD40 | CD40 molecule. (280 aa) |
| | CAB39 | Calcium binding protein 39. (341 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (344 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) |
| | NOD2 | Uncharacterized protein. (982 aa) |
| | DDX3X | Uncharacterized protein; Belongs to the DEAD box helicase family. (661 aa) |
| | PIK3R6 | Phosphoinositide-3-kinase regulatory subunit 6. (762 aa) |
| | EPHA4 | EPH receptor A4. (986 aa) |
| | CCND2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (292 aa) |
| | DAZAP2 | DAZ associated protein 2. (168 aa) |
| | KITLG | Processed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity); Belongs to the SCF family. (274 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (475 aa) |
| | TNFRSF11A | TNF receptor superfamily member 11a. (588 aa) |
| | PIH1D1 | PIH1 domain containing 1. (290 aa) |
| | MST1R | Macrophage stimulating 1 receptor. (1401 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) |
| | DVL2 | Dishevelled segment polarity protein 2. (736 aa) |
| | RAPGEF2 | Rap guanine nucleotide exchange factor 2. (1675 aa) |
| | ERN1 | Endoplasmic reticulum to nucleus signaling 1. (955 aa) |
| | AJUBA | Ajuba LIM protein. (571 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1250 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (555 aa) |
| | HTR2B | 5-hydroxytryptamine receptor 2B. (480 aa) |
| | ADIPOQ | C1q domain-containing protein. (283 aa) |
| | CSF1R | Colony stimulating factor 1 receptor. (958 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | CCND3 | Cyclin D3; Belongs to the cyclin family. (292 aa) |
| | FAM20A | FAM20A golgi associated secretory pathway pseudokinase. (535 aa) |
| | ETAA1 | ETAA1 activator of ATR kinase. (903 aa) |
| | FGD2 | FYVE, RhoGEF and PH domain containing 2. (656 aa) |
| | SLC27A1 | Solute carrier family 27 member 1. (646 aa) |
