(17 nodes) Nephron tubule formation network (Capra hircus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IRX1	Iroquois homeobox 1. (475 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
	GREM1	Gremlin. (184 aa)
	IRX2	Iroquois homeobox 2. (482 aa)
	IRX3	Iroquois homeobox 3. (503 aa)
	HNF1B	HNF1 homeobox B. (558 aa)
	SOX8	SRY-box transcription factor 8. (534 aa)
	OSR1	Odd-skipped related transcription factor 1. (267 aa)
	SOX9	SRY-box transcription factor 9. (525 aa)
	HES5	Hes family bHLH transcription factor 5. (165 aa)
	GDNF	Glial cell derived neurotrophic factor. (211 aa)
	WNT6	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
	SIX1	SIX homeobox 1. (284 aa)
	GATA3	GATA binding protein 3. (467 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	HS2ST1	Uncharacterized protein. (356 aa)
	WNT9B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTNNB1	GATA3	ENSCHIP00000031016	ENSCHIP00000030187	Catenin beta 1.	GATA binding protein 3.	0.435
CTNNB1	HES5	ENSCHIP00000031016	ENSCHIP00000025014	Catenin beta 1.	Hes family bHLH transcription factor 5.	0.449
CTNNB1	NOG	ENSCHIP00000031016	ENSCHIP00000005264	Catenin beta 1.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.707
CTNNB1	SOX8	ENSCHIP00000031016	ENSCHIP00000016757	Catenin beta 1.	SRY-box transcription factor 8.	0.590
CTNNB1	SOX9	ENSCHIP00000031016	ENSCHIP00000024523	Catenin beta 1.	SRY-box transcription factor 9.	0.937
CTNNB1	WNT6	ENSCHIP00000031016	ENSCHIP00000027516	Catenin beta 1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.791
CTNNB1	WNT9B	ENSCHIP00000031016	ENSCHIP00000033475	Catenin beta 1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.727
GATA3	CTNNB1	ENSCHIP00000030187	ENSCHIP00000031016	GATA binding protein 3.	Catenin beta 1.	0.435
GATA3	SIX1	ENSCHIP00000030187	ENSCHIP00000029952	GATA binding protein 3.	SIX homeobox 1.	0.567
GATA3	SOX9	ENSCHIP00000030187	ENSCHIP00000024523	GATA binding protein 3.	SRY-box transcription factor 9.	0.509
GDNF	NOG	ENSCHIP00000027133	ENSCHIP00000005264	Glial cell derived neurotrophic factor.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.754
GDNF	SIX1	ENSCHIP00000027133	ENSCHIP00000029952	Glial cell derived neurotrophic factor.	SIX homeobox 1.	0.474
GDNF	WNT9B	ENSCHIP00000027133	ENSCHIP00000033475	Glial cell derived neurotrophic factor.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.598
HES5	CTNNB1	ENSCHIP00000025014	ENSCHIP00000031016	Hes family bHLH transcription factor 5.	Catenin beta 1.	0.449
HES5	SOX9	ENSCHIP00000025014	ENSCHIP00000024523	Hes family bHLH transcription factor 5.	SRY-box transcription factor 9.	0.479
IRX1	IRX2	ENSCHIP00000018410	ENSCHIP00000007898	Iroquois homeobox 1.	Iroquois homeobox 2.	0.536
IRX1	SOX9	ENSCHIP00000018410	ENSCHIP00000024523	Iroquois homeobox 1.	SRY-box transcription factor 9.	0.546
IRX2	IRX1	ENSCHIP00000007898	ENSCHIP00000018410	Iroquois homeobox 2.	Iroquois homeobox 1.	0.536
IRX2	IRX3	ENSCHIP00000007898	ENSCHIP00000013510	Iroquois homeobox 2.	Iroquois homeobox 3.	0.535
IRX3	IRX2	ENSCHIP00000013510	ENSCHIP00000007898	Iroquois homeobox 3.	Iroquois homeobox 2.	0.535