STRINGSTRING
HOXA11 HOXA11 TMEM59L TMEM59L TFAP2B TFAP2B GZF1 GZF1 NOG NOG ENSCHIP00000005724 ENSCHIP00000005724 HS3ST3A1 HS3ST3A1 DLG1 DLG1 ADAMTS16 ADAMTS16 GREM1 GREM1 LAMA5 LAMA5 IRX2 IRX2 COMMD5 COMMD5 TACSTD2 TACSTD2 BMP2 BMP2 DCHS1 DCHS1 WT1 WT1 KLHL3 KLHL3 HEYL HEYL AQP11 AQP11 PTCH1 PTCH1 IRX3 IRX3 GLI3 GLI3 UMOD UMOD TCF21 TCF21 FAT4 FAT4 HNF1B HNF1B MEF2C MEF2C BCL2 BCL2 PKD1 PKD1 SOX8 SOX8 FGF8 FGF8 ILK ILK GREB1 GREB1 LZTS2 LZTS2 IRX1 IRX1 HES1 HES1 FGF2 FGF2 GPC3 GPC3 WNT1 WNT1 NPNT NPNT SMAD4 SMAD4 PAX8 PAX8 OSR1 OSR1 PKD2 PKD2 WNK4 WNK4 DLL1 DLL1 JAG1 JAG1 CALB1 CALB1 BMP4 BMP4 NOTCH1 NOTCH1 FMN1 FMN1 SOX9 SOX9 WNT11 WNT11 HES5 HES5 EYA1 EYA1 LHX1 LHX1 NOTCH2 NOTCH2 GDNF GDNF MTSS1 MTSS1 WNT6 WNT6 SHH SHH CTNNBIP1 CTNNBIP1 HS3ST3B1 HS3ST3B1 DLG2 DLG2 SIX1 SIX1 GATA3 GATA3 AHI1 AHI1 CTNNB1 CTNNB1 GREB1L GREB1L HS2ST1 HS2ST1 KIF26B KIF26B AQP1 AQP1 FGF1 FGF1 PAX2 PAX2 WNT9B WNT9B LGR4 LGR4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HOXA11Homeobox A11. (317 aa)
TMEM59LTransmembrane protein 59 like. (349 aa)
TFAP2BTranscription factor AP-2 beta. (476 aa)
GZF1GDNF inducible zinc finger protein 1. (710 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
ENSCHIP00000005724Uncharacterized protein. (62 aa)
HS3ST3A1Sulfotransferase; Belongs to the sulfotransferase 1 family. (406 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (927 aa)
ADAMTS16ADAM metallopeptidase with thrombospondin type 1 motif 16. (1279 aa)
GREM1Gremlin. (184 aa)
LAMA5Laminin subunit alpha 5. (2263 aa)
IRX2Iroquois homeobox 2. (482 aa)
COMMD5COMM domain containing 5. (224 aa)
TACSTD2Tumor associated calcium signal transducer 2. (315 aa)
BMP2TGF_BETA_2 domain-containing protein. (381 aa)
DCHS1Dachsous cadherin-related 1. (3258 aa)
WT1WT1 transcription factor. (450 aa)
KLHL3Kelch like family member 3. (610 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
AQP11Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (271 aa)
PTCH1Patched 1. (1453 aa)
IRX3Iroquois homeobox 3. (503 aa)
GLI3GLI family zinc finger 3. (1614 aa)
UMODUromodulin. (643 aa)
TCF21Transcription factor 21. (179 aa)
FAT4FAT atypical cadherin 4. (4982 aa)
HNF1BHNF1 homeobox B. (558 aa)
MEF2CMADS-box domain-containing protein. (441 aa)
BCL2BH4_2 domain-containing protein. (229 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4303 aa)
SOX8SRY-box transcription factor 8. (534 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
ILKIntegrin linked kinase. (452 aa)
GREB1Uncharacterized protein. (1944 aa)
LZTS2Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (672 aa)
IRX1Iroquois homeobox 1. (475 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
GPC3Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (509 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
NPNTNephronectin. (606 aa)
SMAD4Mothers against decapentaplegic homolog. (513 aa)
PAX8Paired box 8. (457 aa)
OSR1Odd-skipped related transcription factor 1. (267 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (978 aa)
WNK4WNK lysine deficient protein kinase 4. (1235 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (724 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
CALB1Calbindin 1. (261 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
NOTCH1Notch receptor 1. (2508 aa)
FMN1Formin 1. (1435 aa)
SOX9SRY-box transcription factor 9. (525 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
HES5Hes family bHLH transcription factor 5. (165 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (618 aa)
LHX1LIM homeobox 1. (406 aa)
NOTCH2Notch receptor 2. (2471 aa)
GDNFGlial cell derived neurotrophic factor. (211 aa)
MTSS1MTSS I-BAR domain containing 1. (737 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
CTNNBIP1Catenin beta interacting protein 1. (81 aa)
HS3ST3B1Sulfotransferase; Belongs to the sulfotransferase 1 family. (388 aa)
DLG2Discs large MAGUK scaffold protein 2. (901 aa)
SIX1SIX homeobox 1. (284 aa)
GATA3GATA binding protein 3. (467 aa)
AHI1Abelson helper integration site 1. (1194 aa)
CTNNB1Catenin beta 1. (781 aa)
GREB1LGREB1 like retinoic acid receptor coactivator. (1911 aa)
HS2ST1Uncharacterized protein. (356 aa)
KIF26BKinesin family member 26B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2112 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
PAX2Paired box 2. (467 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (951 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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