16 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
	NOTCH2	Notch receptor 2. (2471 aa)
	ENSCHIP00000030069	PDZ domain-containing protein. (123 aa)
	ASXL1	ASXL transcriptional regulator 1. (1536 aa)
	PROM1	Prominin 1. (855 aa)
	NPHS1	NPHS1 adhesion molecule, nephrin. (1233 aa)
	MYO1E	Myosin IE; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1113 aa)
	EDNRB	Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (441 aa)
	PTPRO	Protein tyrosine phosphatase receptor type O. (1216 aa)
	IQGAP1	IQ motif containing GTPase activating protein 1. (1657 aa)
	EXT1	Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (446 aa)
	NPHS2	NPHS2 stomatin family member, podocin. (383 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	ENSCHIP00000016631	HARE-HTH domain-containing protein. (59 aa)
	LAMB2	Laminin subunit beta 2. (1802 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	JAG1	ENSCHIP00000023678	ENSCHIP00000023437	Bone morphogenetic protein 4.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.763
EDNRA	EDNRB	ENSCHIP00000021413	ENSCHIP00000008345	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family.	0.964
EDNRB	EDNRA	ENSCHIP00000008345	ENSCHIP00000021413	Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	0.964
IQGAP1	NPHS1	ENSCHIP00000006181	ENSCHIP00000012771	IQ motif containing GTPase activating protein 1.	NPHS1 adhesion molecule, nephrin.	0.646
JAG1	BMP4	ENSCHIP00000023437	ENSCHIP00000023678	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Bone morphogenetic protein 4.	0.763
JAG1	NOTCH2	ENSCHIP00000023437	ENSCHIP00000026116	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 2.	0.999
NOTCH2	JAG1	ENSCHIP00000026116	ENSCHIP00000023437	Notch receptor 2.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.999
NPHS1	IQGAP1	ENSCHIP00000012771	ENSCHIP00000006181	NPHS1 adhesion molecule, nephrin.	IQ motif containing GTPase activating protein 1.	0.646
NPHS1	NPHS2	ENSCHIP00000012771	ENSCHIP00000001614	NPHS1 adhesion molecule, nephrin.	NPHS2 stomatin family member, podocin.	0.972
NPHS1	PTPRO	ENSCHIP00000012771	ENSCHIP00000006636	NPHS1 adhesion molecule, nephrin.	Protein tyrosine phosphatase receptor type O.	0.659
NPHS2	NPHS1	ENSCHIP00000001614	ENSCHIP00000012771	NPHS2 stomatin family member, podocin.	NPHS1 adhesion molecule, nephrin.	0.972
NPHS2	PTPRO	ENSCHIP00000001614	ENSCHIP00000006636	NPHS2 stomatin family member, podocin.	Protein tyrosine phosphatase receptor type O.	0.703
PTPRO	NPHS1	ENSCHIP00000006636	ENSCHIP00000012771	Protein tyrosine phosphatase receptor type O.	NPHS1 adhesion molecule, nephrin.	0.659
PTPRO	NPHS2	ENSCHIP00000006636	ENSCHIP00000001614	Protein tyrosine phosphatase receptor type O.	NPHS2 stomatin family member, podocin.	0.703