(60 nodes) Pyrimidine-containing compound metabolic process network (Capra hircus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Predicted Interactions

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Your Input:
	NME7	Nucleoside diphosphate kinase 7; Belongs to the NDK family. (377 aa)
	DCTPP1	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism. (169 aa)
	TBPL1	TATA-box binding protein like 1. (186 aa)
	NME5	NME/NM23 family member 5; Belongs to the NDK family. (209 aa)
	UCKL1	Uridine-cytidine kinase; Belongs to the uridine kinase family. (552 aa)
	DPYD	Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1033 aa)
	ACPP	Acid phosphatase, prostate; Belongs to the histidine acid phosphatase family. (387 aa)
	UPRT	Uracil phosphoribosyltransferase homolog. (306 aa)
	ENSCHIP00000016608	dUTPase domain-containing protein. (181 aa)
	TK1	Thymidine kinase. (238 aa)
	ENTPD4	Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family. (616 aa)
	ENSCHIP00000018091	Uncharacterized protein. (55 aa)
	NME1	Nucleoside diphosphate kinase. (157 aa)
	UPP2	Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (330 aa)
	ENSCHIP00000018720	dUTPase domain-containing protein. (199 aa)
	NT5M	5',3'-nucleotidase, mitochondrial. (225 aa)
	THTPA	Thiamine-triphosphatase; Hydrolase highly specific for thiamine triphosphate (ThTP). (225 aa)
	TET3	Tet methylcytosine dioxygenase 3. (1640 aa)
	TET2	Tet methylcytosine dioxygenase 2. (2009 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
	ENSCHIP00000023015	dUTPase domain-containing protein. (121 aa)
	NME3	Nucleoside diphosphate kinase. (169 aa)
	NME2	Nucleoside diphosphate kinase. (152 aa)
	CAD	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2242 aa)
	ENSCHIP00000026501	Uncharacterized protein. (85 aa)
	NME4	Nucleoside diphosphate kinase. (187 aa)
	UCK2	Uridine-cytidine kinase; Belongs to the uridine kinase family. (261 aa)
	CDADC1	Cytidine and dCMP deaminase domain containing 1. (499 aa)
	DTYMK	Deoxythymidylate kinase. (212 aa)
	NT5C	5', 3'-nucleotidase, cytosolic. (216 aa)
	CPS1	Carbamoyl-phosphate synthase 1. (1500 aa)
	UMPS	Uridine monophosphate synthetase. (507 aa)
	DCK	Deoxycytidine kinase. (260 aa)
	DPYS	Dihydropyrimidinase. (516 aa)
	APOBEC2	Apolipoprotein B mRNA editing enzyme catalytic subunit 2. (224 aa)
	NME6	Nucleoside diphosphate kinase. (186 aa)
	LOC102184324	Uncharacterized protein. (374 aa)
	CTPS1	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (591 aa)
	ENTPD5	Ectonucleoside triphosphate diphosphohydrolase 5 (inactive); Belongs to the GDA1/CD39 NTPase family. (428 aa)
	CDA	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (146 aa)
	TYMS	Thymidylate synthetase. (355 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (396 aa)
	DHODH	Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (395 aa)
	ENPP3	Ectonucleotide pyrophosphatase/phosphodiesterase 3. (874 aa)
	CTPS2	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (586 aa)
	UPP1	Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (312 aa)
	UPB1	Beta-ureidopropionase 1. (325 aa)
	NME9	NME/NM23 family member 9; Belongs to the NDK family. (342 aa)
	TPK1	Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family. (243 aa)
	CMPK2	Cytidine/uridine monophosphate kinase 2. (458 aa)
	LOC106502146	CMP/dCMP-type deaminase domain-containing protein. (213 aa)
	AICDA	Activation induced cytidine deaminase. (199 aa)
	ALDH6A1	Aldehyde dehydrogenase 6 family member A1. (535 aa)
	APOBEC1	Apolipoprotein B mRNA editing enzyme catalytic subunit 1. (241 aa)
	UCK1	Uridine-cytidine kinase; Belongs to the uridine kinase family. (277 aa)
	DCTD	Deoxycytidylate deaminase. (178 aa)
	DUT	dUTPase domain-containing protein. (242 aa)
	ENTPD7	Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (604 aa)
	TET1	Tet methylcytosine dioxygenase 1. (2168 aa)
	CMPK1	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (228 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AICDA	APOBEC2	ENSCHIP00000009604	ENSCHIP00000032325	Activation induced cytidine deaminase.	Apolipoprotein B mRNA editing enzyme catalytic subunit 2.	0.421
AICDA	CDA	ENSCHIP00000009604	ENSCHIP00000033674	Activation induced cytidine deaminase.	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	0.680
AICDA	DCK	ENSCHIP00000009604	ENSCHIP00000030481	Activation induced cytidine deaminase.	Deoxycytidine kinase.	0.484
AICDA	TET2	ENSCHIP00000009604	ENSCHIP00000021748	Activation induced cytidine deaminase.	Tet methylcytosine dioxygenase 2.	0.477
AICDA	TET3	ENSCHIP00000009604	ENSCHIP00000020625	Activation induced cytidine deaminase.	Tet methylcytosine dioxygenase 3.	0.431
APOBEC1	APOBEC2	ENSCHIP00000008849	ENSCHIP00000032325	Apolipoprotein B mRNA editing enzyme catalytic subunit 1.	Apolipoprotein B mRNA editing enzyme catalytic subunit 2.	0.641
APOBEC1	CDA	ENSCHIP00000008849	ENSCHIP00000033674	Apolipoprotein B mRNA editing enzyme catalytic subunit 1.	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	0.784
APOBEC1	LOC102184324	ENSCHIP00000008849	ENSCHIP00000032712	Apolipoprotein B mRNA editing enzyme catalytic subunit 1.	Uncharacterized protein.	0.507
APOBEC1	LOC106502146	ENSCHIP00000008849	ENSCHIP00000010038	Apolipoprotein B mRNA editing enzyme catalytic subunit 1.	CMP/dCMP-type deaminase domain-containing protein.	0.525
APOBEC1	TET1	ENSCHIP00000008849	ENSCHIP00000005990	Apolipoprotein B mRNA editing enzyme catalytic subunit 1.	Tet methylcytosine dioxygenase 1.	0.441
APOBEC1	TET2	ENSCHIP00000008849	ENSCHIP00000021748	Apolipoprotein B mRNA editing enzyme catalytic subunit 1.	Tet methylcytosine dioxygenase 2.	0.596
APOBEC1	TET3	ENSCHIP00000008849	ENSCHIP00000020625	Apolipoprotein B mRNA editing enzyme catalytic subunit 1.	Tet methylcytosine dioxygenase 3.	0.624
APOBEC2	AICDA	ENSCHIP00000032325	ENSCHIP00000009604	Apolipoprotein B mRNA editing enzyme catalytic subunit 2.	Activation induced cytidine deaminase.	0.421
APOBEC2	APOBEC1	ENSCHIP00000032325	ENSCHIP00000008849	Apolipoprotein B mRNA editing enzyme catalytic subunit 2.	Apolipoprotein B mRNA editing enzyme catalytic subunit 1.	0.641
APOBEC2	CDA	ENSCHIP00000032325	ENSCHIP00000033674	Apolipoprotein B mRNA editing enzyme catalytic subunit 2.	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	0.460
APOBEC2	DCTD	ENSCHIP00000032325	ENSCHIP00000007073	Apolipoprotein B mRNA editing enzyme catalytic subunit 2.	Deoxycytidylate deaminase.	0.598
APOBEC2	LOC102184324	ENSCHIP00000032325	ENSCHIP00000032712	Apolipoprotein B mRNA editing enzyme catalytic subunit 2.	Uncharacterized protein.	0.554
APOBEC2	LOC106502146	ENSCHIP00000032325	ENSCHIP00000010038	Apolipoprotein B mRNA editing enzyme catalytic subunit 2.	CMP/dCMP-type deaminase domain-containing protein.	0.497
APOBEC2	TET2	ENSCHIP00000032325	ENSCHIP00000021748	Apolipoprotein B mRNA editing enzyme catalytic subunit 2.	Tet methylcytosine dioxygenase 2.	0.484
APOBEC2	TET3	ENSCHIP00000032325	ENSCHIP00000020625	Apolipoprotein B mRNA editing enzyme catalytic subunit 2.	Tet methylcytosine dioxygenase 3.	0.462