(31 nodes) Establishment of epithelial cell polarity network (Capra hircus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FOXF1	Forkhead box F1. (391 aa)
	OPHN1	Oligophrenin 1. (436 aa)
	PTK7	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa)
	HES5	Hes family bHLH transcription factor 5. (165 aa)
	FBF1	Fas binding factor 1. (1033 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
	FAT1	FAT atypical cadherin 1. (4643 aa)
	SLC9A3R1	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (386 aa)
	IFT20	Intraflagellar transport 20. (156 aa)
	CYTH3	Cytohesin 3. (401 aa)
	SYNE4	KASH domain-containing protein. (284 aa)
	ENSCHIP00000001275	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (154 aa)
	GOLPH3	Golgi phosphoprotein 3. (298 aa)
	CAMSAP3	Calmodulin regulated spectrin associated protein family member 3. (1246 aa)
	ARF6	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
	MYO9A	Myosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2630 aa)
	FRMD4A	FERM domain containing 4A. (1048 aa)
	MSN	Moesin. (666 aa)
	SIPA1L3	Signal induced proliferation associated 1 like 3. (1816 aa)
	ENSCHIP00000011371	Uncharacterized protein. (193 aa)
	RHOA	Ras-like protein family member A. (193 aa)
	CDC42	Uncharacterized protein. (191 aa)
	SH3BP1	Uncharacterized protein. (601 aa)
	FRMD4B	FERM domain containing 4B. (1035 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
	TTC8	Tetratricopeptide repeat domain 8. (511 aa)
	PKD1	Polycystin 1, transient receptor potential channel interacting. (4303 aa)
	FERMT1	Fermitin family member 1. (679 aa)
	LOC102176514	Uncharacterized protein. (182 aa)
	HES1	Hes family bHLH transcription factor 1. (280 aa)
	TCF15	Transcription factor 15. (197 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARF6	CDC42	ENSCHIP00000004584	ENSCHIP00000012064	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Uncharacterized protein.	0.785
ARF6	CYTH3	ENSCHIP00000004584	ENSCHIP00000030226	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Cytohesin 3.	0.993
ARF6	ENSCHIP00000001275	ENSCHIP00000004584	ENSCHIP00000001275	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	0.901
ARF6	FRMD4A	ENSCHIP00000004584	ENSCHIP00000008627	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	FERM domain containing 4A.	0.502
ARF6	MSN	ENSCHIP00000004584	ENSCHIP00000010531	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Moesin.	0.460
ARF6	MYO9A	ENSCHIP00000004584	ENSCHIP00000008521	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Myosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.525
ARF6	RHOA	ENSCHIP00000004584	ENSCHIP00000011951	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Ras-like protein family member A.	0.734
CDC42	ARF6	ENSCHIP00000012064	ENSCHIP00000004584	Uncharacterized protein.	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	0.785
CDC42	ENSCHIP00000011371	ENSCHIP00000012064	ENSCHIP00000011371	Uncharacterized protein.	Uncharacterized protein.	0.437
CDC42	MSN	ENSCHIP00000012064	ENSCHIP00000010531	Uncharacterized protein.	Moesin.	0.780
CDC42	MYO9A	ENSCHIP00000012064	ENSCHIP00000008521	Uncharacterized protein.	Myosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.757
CDC42	OPHN1	ENSCHIP00000012064	ENSCHIP00000021448	Uncharacterized protein.	Oligophrenin 1.	0.682
CDC42	RHOA	ENSCHIP00000012064	ENSCHIP00000011951	Uncharacterized protein.	Ras-like protein family member A.	0.963
CDC42	SLC9A3R1	ENSCHIP00000012064	ENSCHIP00000007323	Uncharacterized protein.	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.	0.410
CYTH3	ARF6	ENSCHIP00000030226	ENSCHIP00000004584	Cytohesin 3.	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	0.993
CYTH3	ENSCHIP00000001275	ENSCHIP00000030226	ENSCHIP00000001275	Cytohesin 3.	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	0.966
CYTH3	FRMD4A	ENSCHIP00000030226	ENSCHIP00000008627	Cytohesin 3.	FERM domain containing 4A.	0.843
CYTH3	FRMD4B	ENSCHIP00000030226	ENSCHIP00000014499	Cytohesin 3.	FERM domain containing 4B.	0.717
ENSCHIP00000001275	ARF6	ENSCHIP00000001275	ENSCHIP00000004584	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	0.901
ENSCHIP00000001275	CYTH3	ENSCHIP00000001275	ENSCHIP00000030226	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	Cytohesin 3.	0.966