49 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GINS4	DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa)
	ENSCHIP00000015450	BRCT domain-containing protein. (152 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	WRNIP1	WRN helicase interacting protein 1. (640 aa)
	NRM	Nurim. (262 aa)
	LOC108638223	Uncharacterized protein. (145 aa)
	E2F7	E2F transcription factor 7. (911 aa)
	LIG3	DNA ligase. (1004 aa)
	DERPC	DERPC proline and glycine rich nuclear protein. (520 aa)
	SMARCAL1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (930 aa)
	ZRANB3	Zinc finger RANBP2-type containing 3. (1070 aa)
	STOML2	Stomatin like 2. (356 aa)
	METTL4	Methyltransferase like 4; Belongs to the MT-A70-like family. (470 aa)
	TIPIN	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (289 aa)
	DACH1	Dachshund family transcription factor 1. (761 aa)
	CDK2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (346 aa)
	CIZ1	CDKN1A interacting zinc finger protein 1. (842 aa)
	TICRR	TOPBP1 interacting checkpoint and replication regulator. (1900 aa)
	CHTF18	Chromosome transmission fidelity factor 18. (948 aa)
	RFC2	Replication factor C subunit 2. (352 aa)
	INO80	INO80 complex ATPase subunit. (1566 aa)
	BLM	BLM RecQ like helicase. (1429 aa)
	TIMELESS	Timeless circadian regulator. (1206 aa)
	AICDA	Activation induced cytidine deaminase. (199 aa)
	CDT1	Chromatin licensing and DNA replication factor 1. (637 aa)
	RFC3	Replication factor C subunit 3. (356 aa)
	ZNF830	Zinc finger protein 830. (361 aa)
	ENSCHIP00000010204	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (275 aa)
	ENSCHIP00000011218	Uncharacterized protein. (167 aa)
	ATRX	ATRX chromatin remodeler. (2105 aa)
	SSBP1	Uncharacterized protein. (148 aa)
	ENSCHIP00000012571	Uncharacterized protein. (386 aa)
	ZMPSTE24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
	DSCC1	Uncharacterized protein. (388 aa)
	GINS2	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa)
	NUGGC	Nuclear GTPase, germinal center associated. (794 aa)
	POLG2	DNA polymerase gamma 2, accessory subunit. (485 aa)
	E2F8	E2F transcription factor 8. (866 aa)
	BRCA2	BRCA2 DNA repair associated. (3405 aa)
	GINS3	GINS complex subunit 3. (216 aa)
	RFC4	Replication factor C subunit 4. (364 aa)
	ENDOG	Endonuclease. (299 aa)
	DBF4	DBF4 zinc finger. (675 aa)
	DONSON	Downstream neighbor of SON. (561 aa)
	MCIDAS	Multiciliate differentiation and DNA synthesis associated cell cycle protein. (374 aa)
	GMNN	Geminin DNA replication inhibitor. (186 aa)
	CDC7	Cell division cycle 7. (576 aa)
	FBXO5	F-box protein 5. (448 aa)
	KAT7	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AICDA	NUGGC	ENSCHIP00000009604	ENSCHIP00000016707	Activation induced cytidine deaminase.	Nuclear GTPase, germinal center associated.	0.557
ATRX	BRCA2	ENSCHIP00000011584	ENSCHIP00000024039	ATRX chromatin remodeler.	BRCA2 DNA repair associated.	0.579
ATRX	PCNA	ENSCHIP00000011584	ENSCHIP00000015091	ATRX chromatin remodeler.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.480
BLM	BRCA2	ENSCHIP00000006552	ENSCHIP00000024039	BLM RecQ like helicase.	BRCA2 DNA repair associated.	0.830
BLM	CDC7	ENSCHIP00000006552	ENSCHIP00000033187	BLM RecQ like helicase.	Cell division cycle 7.	0.410
BLM	CHTF18	ENSCHIP00000006552	ENSCHIP00000004856	BLM RecQ like helicase.	Chromosome transmission fidelity factor 18.	0.652
BLM	ENSCHIP00000010204	ENSCHIP00000006552	ENSCHIP00000010204	BLM RecQ like helicase.	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	0.706
BLM	FBXO5	ENSCHIP00000006552	ENSCHIP00000032887	BLM RecQ like helicase.	F-box protein 5.	0.487
BLM	INO80	ENSCHIP00000006552	ENSCHIP00000006550	BLM RecQ like helicase.	INO80 complex ATPase subunit.	0.412
BLM	KAT7	ENSCHIP00000006552	ENSCHIP00000031486	BLM RecQ like helicase.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.450
BLM	PCNA	ENSCHIP00000006552	ENSCHIP00000015091	BLM RecQ like helicase.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.760
BLM	RFC2	ENSCHIP00000006552	ENSCHIP00000004939	BLM RecQ like helicase.	Replication factor C subunit 2.	0.673
BLM	RFC3	ENSCHIP00000006552	ENSCHIP00000010064	BLM RecQ like helicase.	Replication factor C subunit 3.	0.713
BLM	RFC4	ENSCHIP00000006552	ENSCHIP00000023106	BLM RecQ like helicase.	Replication factor C subunit 4.	0.702
BLM	TIMELESS	ENSCHIP00000006552	ENSCHIP00000007177	BLM RecQ like helicase.	Timeless circadian regulator.	0.740
BLM	TIPIN	ENSCHIP00000006552	ENSCHIP00000000682	BLM RecQ like helicase.	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	0.706
BLM	WRNIP1	ENSCHIP00000006552	ENSCHIP00000013186	BLM RecQ like helicase.	WRN helicase interacting protein 1.	0.722
BRCA2	ATRX	ENSCHIP00000024039	ENSCHIP00000011584	BRCA2 DNA repair associated.	ATRX chromatin remodeler.	0.579
BRCA2	BLM	ENSCHIP00000024039	ENSCHIP00000006552	BRCA2 DNA repair associated.	BLM RecQ like helicase.	0.830
BRCA2	CDK2	ENSCHIP00000024039	ENSCHIP00000003142	BRCA2 DNA repair associated.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.862