(21 nodes) Ligand-gated anion channel activity network (Capra hircus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	GLRA1	Glycine receptor alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (451 aa)
	GABRG1	Gamma-aminobutyric acid type A receptor gamma1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (465 aa)
	CFTR	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1524 aa)
	GLRA4	Glycine receptor alpha 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (500 aa)
	GABRB1	Uncharacterized protein. (160 aa)
	GABRA1	Gamma-aminobutyric acid type A receptor alpha1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (456 aa)
	GLRA2	Glycine receptor alpha 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (452 aa)
	GABRB3	Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (493 aa)
	GABRA6	Gamma-aminobutyric acid type A receptor alpha6 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (425 aa)
	GABRG2	Gamma-aminobutyric acid type A receptor gamma2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (475 aa)
	GABRA5	Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
	GABRG3	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (387 aa)
	GLRB	Glycine receptor beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (497 aa)
	GABRB2	Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
	GABRA3	Neur_chan_LBD domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (211 aa)
	ENSCHIP00000013125	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (421 aa)
	ENSCHIP00000012993	Uncharacterized protein. (146 aa)
	GABRE	Gamma-aminobutyric acid type A receptor epsilon subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (439 aa)
	GABRA2	Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (451 aa)
	GLRA3	Glycine receptor alpha 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (464 aa)
	GABRA4	Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (555 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCHIP00000012993	ENSCHIP00000013125	ENSCHIP00000012993	ENSCHIP00000013125	Uncharacterized protein.	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.629
ENSCHIP00000012993	GABRA1	ENSCHIP00000012993	ENSCHIP00000020888	Uncharacterized protein.	Gamma-aminobutyric acid type A receptor alpha1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.798
ENSCHIP00000012993	GABRA2	ENSCHIP00000012993	ENSCHIP00000032416	Uncharacterized protein.	Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.677
ENSCHIP00000012993	GABRA3	ENSCHIP00000012993	ENSCHIP00000015230	Uncharacterized protein.	Neur_chan_LBD domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.639
ENSCHIP00000012993	GABRA4	ENSCHIP00000012993	ENSCHIP00000007731	Uncharacterized protein.	Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.579
ENSCHIP00000012993	GABRA5	ENSCHIP00000012993	ENSCHIP00000028092	Uncharacterized protein.	Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.639
ENSCHIP00000012993	GABRA6	ENSCHIP00000012993	ENSCHIP00000024434	Uncharacterized protein.	Gamma-aminobutyric acid type A receptor alpha6 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.579
ENSCHIP00000012993	GABRB1	ENSCHIP00000012993	ENSCHIP00000020694	Uncharacterized protein.	Uncharacterized protein.	0.629
ENSCHIP00000012993	GABRB2	ENSCHIP00000012993	ENSCHIP00000029891	Uncharacterized protein.	Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.629
ENSCHIP00000012993	GABRB3	ENSCHIP00000012993	ENSCHIP00000024255	Uncharacterized protein.	Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.688
ENSCHIP00000013125	ENSCHIP00000012993	ENSCHIP00000013125	ENSCHIP00000012993	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Uncharacterized protein.	0.629
ENSCHIP00000013125	GABRA1	ENSCHIP00000013125	ENSCHIP00000020888	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Gamma-aminobutyric acid type A receptor alpha1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.820
ENSCHIP00000013125	GABRA2	ENSCHIP00000013125	ENSCHIP00000032416	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.672
ENSCHIP00000013125	GABRA3	ENSCHIP00000013125	ENSCHIP00000015230	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Neur_chan_LBD domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.767
ENSCHIP00000013125	GABRA4	ENSCHIP00000013125	ENSCHIP00000007731	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.577
ENSCHIP00000013125	GABRA5	ENSCHIP00000013125	ENSCHIP00000028092	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.667
ENSCHIP00000013125	GABRA6	ENSCHIP00000013125	ENSCHIP00000024434	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Gamma-aminobutyric acid type A receptor alpha6 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.621
ENSCHIP00000013125	GABRB1	ENSCHIP00000013125	ENSCHIP00000020694	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Uncharacterized protein.	0.443
ENSCHIP00000013125	GABRE	ENSCHIP00000013125	ENSCHIP00000032185	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Gamma-aminobutyric acid type A receptor epsilon subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.467
ENSCHIP00000013125	GABRG1	ENSCHIP00000013125	ENSCHIP00000018584	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Gamma-aminobutyric acid type A receptor gamma1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.647