STRINGSTRING
LOC102168673 LOC102168673 LEP LEP VTCN1 VTCN1 LOC108633234 LOC108633234 LOC108638256 LOC108638256 TNFSF4 TNFSF4 IDO1 IDO1 IRF1 IRF1 CD6 CD6 PTPN6 PTPN6 TMEM131L TMEM131L ZBTB1 ZBTB1 TIGIT TIGIT NR4A3 NR4A3 BTNL2 BTNL2 DUSP10 DUSP10 LOC102180664 LOC102180664 CRTAM CRTAM ENSCHIP00000022485 ENSCHIP00000022485 SASH3 SASH3 GPAM GPAM CBFB CBFB IL7R IL7R LOC102183203 LOC102183203 TNFSF14 TNFSF14 ANXA1 ANXA1 IGF2 IGF2 CARD11 CARD11 IL18 IL18 LRRC1 LRRC1 LOC102178618 LOC102178618 DPP4 DPP4 BMP4 BMP4 ZDHHC21 ZDHHC21 ENSCHIP00000024183 ENSCHIP00000024183 CD44 CD44 CORO1A CORO1A CD27 CD27 ABL1 ABL1 STAT5B STAT5B ZP3 ZP3 ZC3H12A ZC3H12A TBX21 TBX21 PELI1 PELI1 MAD1L1 MAD1L1 ARG1 ARG1 LOC102186727 LOC102186727 STAT5A STAT5A PTPRC PTPRC GPNMB GPNMB EGR3 EGR3 CD47 CD47 IL12A IL12A ALOX5 ALOX5 PYCARD PYCARD LOXL3 LOXL3 IL21 IL21 LOC108633275 LOC108633275 AKT1 AKT1 GLMN GLMN SHH SHH DUSP3 DUSP3 XBP1 XBP1 FGL2 FGL2 SELENOK SELENOK LAX1 LAX1 LOC102180339 LOC102180339 AIF1 AIF1 LRRC32 LRRC32 THY1 THY1 CBLB CBLB PDCD1LG2 PDCD1LG2 IL1B IL1B IL15 IL15 ENSCHIP00000029415 ENSCHIP00000029415 CD28 CD28 SELP SELP IL2 IL2 DLG2 DLG2 NOD2 NOD2 SOCS6 SOCS6 ICOS ICOS PIK3R6 PIK3R6 GATA3 GATA3 CLEC4G CLEC4G KITLG KITLG LEF1 LEF1 IGFBP2 IGFBP2 SHB SHB NDFIP1 NDFIP1 LOC102180664-2 LOC102180664-2 ADTRP ADTRP CCL21 CCL21 ZBTB7B ZBTB7B ENSCHIP00000031698 ENSCHIP00000031698 IL1RL2 IL1RL2 ERBB2 ERBB2 ENSCHIP00000031738 ENSCHIP00000031738 CEBPB CEBPB CCL25 CCL25 TNFRSF21 TNFRSF21 ZP4 ZP4 PPARA PPARA NFKBIZ NFKBIZ TWSG1 TWSG1 BCL6 BCL6 LOC102187998 LOC102187998 PPP3CA PPP3CA IL12RB2 IL12RB2 SKAP1 SKAP1 TFRC TFRC ADA ADA IL12RB1 IL12RB1 NKAP NKAP ZMIZ1 ZMIZ1 DLG5 DLG5 LOC102183503 LOC102183503 GIMAP5 GIMAP5 ENSCHIP00000000943 ENSCHIP00000000943 SOCS1 SOCS1 LOC102189615 LOC102189615 SOCS5 SOCS5 RC3H1 RC3H1 TNFSF13B TNFSF13B PCK1 PCK1 TNFSF9 TNFSF9 FUT9 FUT9 HSPD1 HSPD1 CD5 CD5 VSIR VSIR SELE SELE PAG1 PAG1 FAM49B FAM49B IL2RG IL2RG LOC102170800 LOC102170800 RHOH RHOH RIPOR2 RIPOR2 ENSCHIP00000003765 ENSCHIP00000003765 IL6ST IL6ST CTLA4 CTLA4 EFNB1 EFNB1 SOX12 SOX12 FADD FADD ZBTB16 ZBTB16 HHLA2 HHLA2 TNFAIP8L2 TNFAIP8L2 TNF TNF ENSCHIP00000004646 ENSCHIP00000004646 PRDX2 PRDX2 ENSCHIP00000004806 ENSCHIP00000004806 SLAMF1 SLAMF1 HLA-DMA HLA-DMA CD80 CD80 LOC102186442 LOC102186442 CD81 CD81 LOC102184087 LOC102184087 ENSCHIP00000005724 ENSCHIP00000005724 NCKAP1L NCKAP1L MYB MYB NRARP NRARP ENSCHIP00000006184 ENSCHIP00000006184 FUT7 FUT7 DLG1 DLG1 RASGRP1 RASGRP1 ENSCHIP00000006450 ENSCHIP00000006450 NCK2 NCK2 HFE HFE HLA-DOB HLA-DOB CAHI-DQA2 CAHI-DQA2 CHST2 CHST2 FOXJ1 FOXJ1 IL36B IL36B EFNB3 EFNB3 ITPKB ITPKB WNT10B WNT10B IL23A IL23A PRKCZ PRKCZ CXCL12 CXCL12 DHPS DHPS GCNT1 GCNT1 HAS2 HAS2 SPTA1 SPTA1 TGFBR2 TGFBR2 PRKAR1A PRKAR1A BCL10 BCL10 TGFB1 TGFB1 TARM1 TARM1 ZC3H8 ZC3H8 IRAK1 IRAK1 WNK1 WNK1 SYK SYK ZAP70 ZAP70 RPS3 RPS3 CD3E CD3E NCK1 NCK1 SIRPA SIRPA CCL28 CCL28 ST3GAL4 ST3GAL4 LAG3 LAG3 SOX13 SOX13 LOC108635823 LOC108635823 LOC106503481 LOC106503481 FGL1 FGL1 HLA-DRA HLA-DRA ITCH ITCH IL7 IL7 RAG1 RAG1 VSIG4 VSIG4 LOC102179937 LOC102179937 FUT4 FUT4 ENSCHIP00000011371 ENSCHIP00000011371 CASP3 CASP3 ENSCHIP00000011519 ENSCHIP00000011519 PTPN2 PTPN2 LCK LCK AGER AGER RHOA RHOA PAWR PAWR CD74 CD74 ITGB2 ITGB2 SART1 SART1 IFNG IFNG PLA2G2F PLA2G2F IHH IHH MALT1 MALT1 BMI1 BMI1 LOC102170474 LOC102170474 AMBRA1 AMBRA1 TNFRSF13C TNFRSF13C IL12B IL12B SLC7A1 SLC7A1 HAVCR2 HAVCR2 ARG2 ARG2 CD274 CD274 CD83 CD83 IL4I1 IL4I1 HLX HLX ENSCHIP00000012512 ENSCHIP00000012512 FOXP3 FOXP3 HLA-DOA HLA-DOA PTPN22 PTPN22 ENSCHIP00000012902 ENSCHIP00000012902 LGALS1 LGALS1 DOCK8 DOCK8 RARA RARA IL27RA IL27RA ILDR2 ILDR2 TNFSF11 TNFSF11 RELA RELA GLI3 GLI3 EPHB6 EPHB6 BAD BAD KAT5 KAT5 LOC102173969 LOC102173969 TSPAN32 TSPAN32 ETS1 ETS1 LOC102171800 LOC102171800 ENSCHIP00000015156 ENSCHIP00000015156 TRAF6 TRAF6 ENSCHIP00000015226 ENSCHIP00000015226 DRB3 DRB3 CD86 CD86 PRKCQ PRKCQ LOC106503912 LOC106503912 ASS1 ASS1 VNN1 VNN1 HES1 HES1 ENSCHIP00000018611 ENSCHIP00000018611 FCHO1 FCHO1 FLOT2 FLOT2 RASAL3 RASAL3 LGALS7 LGALS7 FOXO3 FOXO3 ENSCHIP00000019274 ENSCHIP00000019274 CCL19 CCL19 LOC102187672 LOC102187672 RIPK2 RIPK2 IL20RB IL20RB TYK2 TYK2 MARCHF7 MARCHF7 AP3B1 AP3B1 IGF1 IGF1 CCDC88B CCDC88B CCR7 CCR7 IL4 IL4 ADAM8 ADAM8 SCRIB SCRIB CAV1 CAV1 RC3H2 RC3H2 SMAD7 SMAD7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102168673Phospholipase A(2). (148 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (192 aa)
VTCN1V-set domain containing T cell activation inhibitor 1. (270 aa)
LOC108633234Phospholipase A(2). (148 aa)
LOC108638256Galectin. (243 aa)
TNFSF4TNF superfamily member 4; Belongs to the tumor necrosis factor family. (182 aa)
IDO1Uncharacterized protein. (410 aa)
IRF1Interferon regulatory factor. (322 aa)
CD6CD6 molecule. (672 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
TMEM131LTransmembrane 131 like. (1599 aa)
ZBTB1Zinc finger and BTB domain containing 1. (644 aa)
TIGITT cell immunoreceptor with Ig and ITIM domains. (277 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (648 aa)
BTNL2Butyrophilin like 2. (522 aa)
DUSP10Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa)
LOC102180664Ig-like domain-containing protein. (266 aa)
CRTAMCytotoxic and regulatory T cell molecule. (414 aa)
ENSCHIP00000022485AIG1-type G domain-containing protein. (295 aa)
SASH3SAM and SH3 domain containing 3. (380 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (844 aa)
CBFBCore-binding factor subunit beta. (187 aa)
IL7RInterleukin 7 receptor. (459 aa)
LOC102183203Amine oxidase. (517 aa)
TNFSF14TNF_2 domain-containing protein. (237 aa)
ANXA1Annexin. (346 aa)
IGF2Insulin-like growth factor II. (179 aa)
CARD11Caspase recruitment domain family member 11. (1154 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
LRRC1Leucine rich repeat containing 1. (517 aa)
LOC102178618AIG1-type G domain-containing protein. (214 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (767 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
ENSCHIP00000024183Uncharacterized protein. (207 aa)
CD44CD44 molecule (Indian blood group). (715 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
CD27CD27 molecule. (270 aa)
ABL1Tyrosine-protein kinase. (1151 aa)
STAT5BSignal transducer and activator of transcription. (808 aa)
ZP3ZP domain-containing protein. (432 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (599 aa)
TBX21T-box transcription factor 21. (533 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (725 aa)
ARG1Arginase. (322 aa)
LOC102186727Ig-like domain-containing protein; Belongs to the MHC class II family. (322 aa)
STAT5ASignal transducer and activator of transcription. (810 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1067 aa)
GPNMBGlycoprotein nmb. (555 aa)
EGR3Early growth response 3. (387 aa)
CD47CD47 molecule. (321 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (238 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
PYCARDPYD and CARD domain containing. (196 aa)
LOXL3Lysyl oxidase like 3. (752 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (157 aa)
LOC108633275TNF_2 domain-containing protein. (230 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (495 aa)
GLMNGlomulin, FKBP associated protein. (592 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)
XBP1BZIP domain-containing protein. (261 aa)
FGL2Fibrinogen like 2. (441 aa)
SELENOKSelenoprotein K. (85 aa)
LAX1Uncharacterized protein. (381 aa)
LOC102180339Galectin-7. (139 aa)
AIF1Allograft inflammatory factor 1. (147 aa)
LRRC32Leucine rich repeat containing 32. (710 aa)
THY1Thy-1 cell surface antigen. (161 aa)
CBLBCbl proto-oncogene B. (983 aa)
PDCD1LG2Programmed cell death 1 ligand 2. (296 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (161 aa)
ENSCHIP00000029415Uncharacterized protein. (294 aa)
CD28CD28 molecule. (228 aa)
SELPSelectin P. (771 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family. (155 aa)
DLG2Discs large MAGUK scaffold protein 2. (901 aa)
NOD2Uncharacterized protein. (982 aa)
SOCS6Uncharacterized protein. (510 aa)
ICOSInducible T cell costimulator. (209 aa)
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (762 aa)
GATA3GATA binding protein 3. (467 aa)
CLEC4GC-type lectin domain family 4 member G. (291 aa)
KITLGProcessed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity); Belongs to the SCF family. (274 aa)
LEF1HMG box domain-containing protein. (430 aa)
IGFBP2Uncharacterized protein. (326 aa)
SHBSH2 domain-containing protein. (507 aa)
NDFIP1Nedd4 family interacting protein 1. (221 aa)
LOC102180664-2Ig-like domain-containing protein. (268 aa)
ADTRPAndrogen dependent TFPI regulating protein. (230 aa)
CCL21C-C motif chemokine ligand 21. (131 aa)
ZBTB7BZinc finger and BTB domain containing 7B. (539 aa)
ENSCHIP00000031698Uncharacterized protein. (321 aa)
IL1RL2Interleukin 1 receptor like 2. (552 aa)
ERBB2Receptor protein-tyrosine kinase. (1250 aa)
ENSCHIP00000031738Galectin. (224 aa)
CEBPBCCAAT/enhancer-binding protein. (307 aa)
CCL25C-C motif chemokine ligand 25. (150 aa)
TNFRSF21TNF receptor superfamily member 21. (652 aa)
ZP4Zona pellucida glycoprotein 4. (531 aa)
PPARAPeroxisome proliferator activated receptor alpha. (470 aa)
NFKBIZMolecule possessing ankyrin-repeats induced by lipopolysaccharide. (719 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (223 aa)
BCL6BCL6 transcription repressor. (706 aa)
LOC102187998Ig-like domain-containing protein. (262 aa)
PPP3CASerine/threonine-protein phosphatase. (527 aa)
IL12RB2Interleukin 12 receptor subunit beta 2. (877 aa)
SKAP1Src kinase associated phosphoprotein 1. (309 aa)
TFRCTransferrin receptor. (790 aa)
ADAAdenosine deaminase. (400 aa)
IL12RB1Interleukin 12 receptor subunit beta 1. (730 aa)
NKAPNFKB activating protein. (370 aa)
ZMIZ1Zinc finger MIZ-type containing 1. (1072 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1946 aa)
LOC102183503AIG1-type G domain-containing protein. (309 aa)
GIMAP5AIG1-type G domain-containing protein. (298 aa)
ENSCHIP00000000943Uncharacterized protein. (356 aa)
SOCS1Suppressor of cytokine signaling 1. (219 aa)
LOC102189615Galectin. (186 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
RC3H1Ring finger and CCCH-type domains 1. (1123 aa)
TNFSF13BTumor necrosis factor superfamily member 13b; Belongs to the tumor necrosis factor family. (280 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
TNFSF9TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (252 aa)
FUT9Fucosyltransferase 9. (359 aa)
HSPD1Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family. (573 aa)
CD5CD5 molecule. (505 aa)
VSIRV-set immunoregulatory receptor. (312 aa)
SELESelectin E. (487 aa)
PAG1Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (434 aa)
FAM49BUncharacterized protein. (350 aa)
IL2RGFibronectin type-III domain-containing protein. (378 aa)
LOC102170800Uncharacterized protein. (537 aa)
RHOHRas homolog family member H. (191 aa)
RIPOR2Uncharacterized protein. (1052 aa)
ENSCHIP00000003765AIG1-type G domain-containing protein. (277 aa)
IL6STInterleukin 6 signal transducer. (918 aa)
CTLA4Cytotoxic T-lymphocyte associated protein 4. (221 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (373 aa)
SOX12Transcription factor SOX. (314 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (209 aa)
ZBTB16Uncharacterized protein. (673 aa)
HHLA2HERV-H LTR-associating 2. (419 aa)
TNFAIP8L2TNF alpha induced protein 8 like 2. (184 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa)
ENSCHIP00000004646Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (118 aa)
PRDX2Thioredoxin domain-containing protein. (198 aa)
ENSCHIP00000004806Ig-like domain-containing protein. (241 aa)
SLAMF1Ig-like domain-containing protein. (338 aa)
HLA-DMAMajor histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (278 aa)
CD80CD80 molecule. (302 aa)
LOC102186442Ig-like domain-containing protein. (290 aa)
CD81Tetraspanin. (236 aa)
LOC102184087Galectin. (342 aa)
ENSCHIP00000005724Uncharacterized protein. (62 aa)
NCKAP1LNCK associated protein 1 like. (1178 aa)
MYBMYB proto-oncogene, transcription factor. (640 aa)
NRARPNOTCH regulated ankyrin repeat protein. (114 aa)
ENSCHIP00000006184Uncharacterized protein. (96 aa)
FUT7Fucosyltransferase 7. (342 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (927 aa)
RASGRP1RAS guanyl releasing protein 1. (773 aa)
ENSCHIP00000006450Uncharacterized protein. (333 aa)
NCK2Cytoplasmic protein. (376 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (356 aa)
HLA-DOBMajor histocompatibility complex, class II, DO beta. (270 aa)
CAHI-DQA2Ig-like domain-containing protein; Belongs to the MHC class II family. (255 aa)
CHST2Sulfotransferase; Belongs to the sulfotransferase 1 family. (527 aa)
FOXJ1Forkhead box J1. (421 aa)
IL36BInterleukin-1. (158 aa)
EFNB3Ephrin B3; Belongs to the ephrin family. (340 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (942 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
IL23AInterleukin 23 subunit alpha. (190 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (116 aa)
DHPSUncharacterized protein. (369 aa)
GCNT1Glucosaminyl (N-acetyl) transferase 1. (428 aa)
HAS2Uncharacterized protein. (552 aa)
SPTA1Spectrin alpha, erythrocytic 1. (2402 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (550 aa)
PRKAR1AProtein kinase cAMP-dependent type I regulatory subunit alpha. (380 aa)
BCL10BCL10 immune signaling adaptor. (230 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
TARM1Uncharacterized protein. (274 aa)
ZC3H8Zinc finger CCCH-type containing 8. (301 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (718 aa)
WNK1WNK lysine deficient protein kinase 1. (2367 aa)
SYKSpleen associated tyrosine kinase. (636 aa)
ZAP70Tyrosine-protein kinase. (622 aa)
RPS3Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa)
CD3ECD3e molecule. (194 aa)
NCK1Cytoplasmic protein. (377 aa)
SIRPAUncharacterized protein. (506 aa)
CCL28C-C motif chemokine ligand 28. (126 aa)
ST3GAL4ST3 beta-galactoside alpha-2,3-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. (336 aa)
LAG3Lymphocyte activating 3. (516 aa)
SOX13SRY-box transcription factor 13. (592 aa)
LOC108635823AIG1-type G domain-containing protein. (297 aa)
LOC106503481Ig-like domain-containing protein. (274 aa)
FGL1Fibrinogen like 1. (315 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (253 aa)
ITCHE3 ubiquitin-protein ligase. (874 aa)
IL7Interleukin 7. (181 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa)
VSIG4V-set and immunoglobulin domain containing 4. (352 aa)
LOC102179937Ig-like domain-containing protein; Belongs to the MHC class II family. (255 aa)
FUT4Fucosyltransferase 4. (398 aa)
ENSCHIP00000011371Uncharacterized protein. (193 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (275 aa)
ENSCHIP00000011519Uncharacterized protein. (439 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (417 aa)
LCKTyrosine-protein kinase. (509 aa)
AGERAdvanced glycosylation end-product specific receptor. (416 aa)
RHOARas-like protein family member A. (193 aa)
PAWRPro-apoptotic WT1 regulator. (345 aa)
CD74CD74 molecule. (261 aa)
ITGB2Integrin beta-2; Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin ITGAM/ITGB2 is also a receptor for factor X. Integrin ITGAD/ITGB2 is a receptor [...] (774 aa)
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (796 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. (166 aa)
PLA2G2FPhospholipase A(2). (196 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
MALT1MALT1 paracaspase. (830 aa)
BMI1RING-type domain-containing protein. (437 aa)
LOC102170474Uncharacterized protein. (238 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1300 aa)
TNFRSF13CTNF receptor superfamily member 13C. (177 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. (331 aa)
SLC7A1Solute carrier family 7 member 1. (629 aa)
HAVCR2Hepatitis A virus cellular receptor 2. (280 aa)
ARG2Arginase. (354 aa)
CD274CD274 molecule. (289 aa)
CD83CD83 molecule. (199 aa)
IL4I1Interleukin 4 induced 1. (582 aa)
HLXH2.0 like homeobox. (488 aa)
ENSCHIP00000012512Uncharacterized protein. (435 aa)
FOXP3Forkhead box P3. (463 aa)
HLA-DOAMajor histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (332 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (795 aa)
ENSCHIP00000012902Ig-like domain-containing protein. (249 aa)
LGALS1Galectin-1; Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. Has hemaglutinating activity towards human erythrocytes. (136 aa)
DOCK8Dedicator of cytokinesis 8; Belongs to the DOCK family. (2091 aa)
RARARetinoic acid receptor alpha. (462 aa)
IL27RAInterleukin 27 receptor subunit alpha. (655 aa)
ILDR2Immunoglobulin like domain containing receptor 2. (642 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (316 aa)
RELARELA proto-oncogene, NF-kB subunit. (571 aa)
GLI3GLI family zinc finger 3. (1614 aa)
EPHB6EPH receptor B6. (1011 aa)
BADBCL2 associated agonist of cell death. (198 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
LOC102173969Ig-like domain-containing protein. (321 aa)
TSPAN32Uncharacterized protein; Belongs to the tetraspanin (TM4SF) family. (411 aa)
ETS1Uncharacterized protein. (485 aa)
LOC102171800Uncharacterized protein. (286 aa)
ENSCHIP00000015156Uncharacterized protein. (101 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (573 aa)
ENSCHIP00000015226KH type-2 domain-containing protein. (204 aa)
DRB3Ig-like domain-containing protein. (269 aa)
CD86Ig-like domain-containing protein. (289 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (711 aa)
LOC106503912Galectin. (116 aa)
ASS1Argininosuccinate synthase 1. (426 aa)
VNN1Vanin 1. (529 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
ENSCHIP00000018611Uncharacterized protein. (183 aa)
FCHO1FCH domain only 1. (887 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (445 aa)
RASAL3RAS protein activator like 3. (1013 aa)
LGALS7Galectin. (139 aa)
FOXO3Forkhead box O3. (672 aa)
ENSCHIP00000019274Ig-like domain-containing protein. (253 aa)
CCL19C-C motif chemokine. (102 aa)
LOC102187672Galectin. (185 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (537 aa)
IL20RBInterleukin 20 receptor subunit beta. (305 aa)
TYK2Tyrosine-protein kinase. (1186 aa)
MARCHF7Membrane associated ring-CH-type finger 7. (713 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1094 aa)
IGF1Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (188 aa)
CCDC88BCoiled-coil domain containing 88B. (1455 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (379 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (135 aa)
ADAM8ADAM metallopeptidase domain 8. (827 aa)
SCRIBScribble planar cell polarity protein. (1582 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
RC3H2Ring finger and CCCH-type domains 2. (1189 aa)
SMAD7Mothers against decapentaplegic homolog. (427 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
Server load: low (32%) [HD]