STRINGSTRING
IFNE IFNE TREM2 TREM2 FADD FADD LOC108636544 LOC108636544 LOC108634604 LOC108634604 CEBPG CEBPG CTSV CTSV LOC108636623 LOC108636623 MFNG MFNG GATA1 GATA1 IFNA IFNA RAG2 RAG2 ENSCHIP00000005136 ENSCHIP00000005136 BATF BATF VEGFA VEGFA NFIL3 NFIL3 LOC102174842 LOC102174842 SLAMF1 SLAMF1 ENSCHIP00000005465 ENSCHIP00000005465 ENSCHIP00000005590 ENSCHIP00000005590 LOC108636628 LOC108636628 NCAPH2 NCAPH2 GPR68 GPR68 IL18R1 IL18R1 LOC108635000 LOC108635000 LOC108636627 LOC108636627 NRARP NRARP FUT7 FUT7 LOC108636629 LOC108636629 PLCL2 PLCL2 LOC108636626 LOC108636626 LOC102181867 LOC102181867 CD4 CD4 ENTPD7 ENTPD7 ADGRG3 ADGRG3 WNT10B WNT10B LOC102180761 LOC102180761 ENSCHIP00000007820 ENSCHIP00000007820 VAV1 VAV1 ATF2 ATF2 TGFBR2 TGFBR2 CLEC4D CLEC4D CDK6 CDK6 IRF2BP2 IRF2BP2 CHD7 CHD7 LOC102189208 LOC102189208 TGFB1 TGFB1 CAMK4 CAMK4 TMEM176B TMEM176B SRF SRF SYK SYK IL6 IL6 LOC108636632 LOC108636632 ZAP70 ZAP70 CDH17 CDH17 IL6R IL6R CD3E CD3E RELB RELB LOC108636620 LOC108636620 GPR183 GPR183 IL31RA IL31RA ENSCHIP00000010278 ENSCHIP00000010278 SOX13 SOX13 LOC108635823 LOC108635823 LOC102181595 LOC102181595 MAFB MAFB CSF2 CSF2 ZBTB46 ZBTB46 IRF8 IRF8 TCF7 TCF7 PDE1B PDE1B LYL1 LYL1 CSF1 CSF1 ADA ADA TMEM98 TMEM98 ENSCHIP00000033427 ENSCHIP00000033427 CD8A CD8A ARMC5 ARMC5 THOC5 THOC5 BCL6 BCL6 F2RL1 F2RL1 FZD7 FZD7 PTK2B PTK2B GBA GBA ERBB2 ERBB2 ZBTB7B ZBTB7B KAT7 KAT7 RORA RORA PRR7 PRR7 MR1 MR1 STAT6 STAT6 FBXO7 FBXO7 ENSCHIP00000031025 ENSCHIP00000031025 CTNNB1 CTNNB1 POU2F2 POU2F2 CCR6 CCR6 LEF1 LEF1 PSEN1 PSEN1 PAX1 PAX1 YY1AP1 YY1AP1 CLEC4G CLEC4G ENSCHIP00000030196 ENSCHIP00000030196 GATA3 GATA3 ENSCHIP00000027739 ENSCHIP00000027739 CD19 CD19 LEPR LEPR NTRK1 NTRK1 BLK BLK IL21 IL21 LFNG LFNG LTBR LTBR GPR18 GPR18 SEMA4A SEMA4A ZFP36L1 ZFP36L1 EGR1 EGR1 ZBTB7A ZBTB7A NOTCH2 NOTCH2 DOCK2 DOCK2 PTPRC PTPRC LYN LYN KIT KIT STAT5A STAT5A CMTM7 CMTM7 JMJD6 JMJD6 TBX21 TBX21 TCIRG1 TCIRG1 MSH2 MSH2 RSAD2 RSAD2 ST3GAL1 ST3GAL1 STAT5B STAT5B GON4L GON4L STK11 STK11 ABL1 ABL1 BATF2 BATF2 BTK BTK PIK3R1 PIK3R1 BMP4 BMP4 DCSTAMP DCSTAMP LOC102178618 LOC102178618 FNIP1 FNIP1 CARD11 CARD11 ANXA1 ANXA1 IL7R IL7R DLL1 DLL1 CBFB CBFB SASH3 SASH3 ENSCHIP00000022485 ENSCHIP00000022485 AXL AXL FOXN1 FOXN1 STAT3 STAT3 ZBTB1 ZBTB1 PATZ1 PATZ1 LOC106502311 LOC106502311 TNFSF8 TNFSF8 POU2AF1 POU2AF1 MTOR MTOR IRF1 IRF1 THEMIS THEMIS BCL11B BCL11B PKNOX1 PKNOX1 SPI1 SPI1 MYH9 MYH9 ATG5 ATG5 LEP LEP TRAF3IP2 TRAF3IP2 ENSCHIP00000021158 ENSCHIP00000021158 ITGB8 ITGB8 LOC108635503 LOC108635503 ITFG2 ITFG2 BATF3 BATF3 LOC108635454 LOC108635454 RC3H2 RC3H2 LOC108635455 LOC108635455 IL4 IL4 CCR7 CCR7 LOC108633160 LOC108633160 WNT1 WNT1 IKZF1 IKZF1 TSHR TSHR RIPK2 RIPK2 FASN FASN BRAF BRAF CCL19 CCL19 ONECUT1 ONECUT1 TSC1 TSC1 ENSCHIP00000019035 ENSCHIP00000019035 HECTD1 HECTD1 CRACR2A CRACR2A LOC106503900 LOC106503900 LOC102188370 LOC102188370 EP300 EP300 TRPM2 TRPM2 NKX2-3 NKX2-3 CD83 CD83 AIRE AIRE LOC102178162 LOC102178162 RABL3 RABL3 PLCG2 PLCG2 CLCF1 CLCF1 IRF4 IRF4 IL12B IL12B AZI2 AZI2 CD79B CD79B MALT1 MALT1 ATM ATM RIPK3 RIPK3 IFNK IFNK ITPKB ITPKB BCL2 BCL2 BCL3 BCL3 BAK1 BAK1 TPD52 TPD52 RUNX2 RUNX2 LY9 LY9 TRAF6 TRAF6 ENSCHIP00000015111 ENSCHIP00000015111 RAB44 RAB44 ENSCHIP00000015031 ENSCHIP00000015031 JAG2 JAG2 DCLRE1C DCLRE1C GAS6 GAS6 LMBR1L LMBR1L DLL4 DLL4 FCER1G FCER1G GLI3 GLI3 NHEJ1 NHEJ1 PREX1 PREX1 CCR9 CCR9 LGALS1 LGALS1 ENSCHIP00000012937 ENSCHIP00000012937 MS4A1 MS4A1 PRTN3 PRTN3 PTPN22 PTPN22 IKZF3 IKZF3 TYRO3 TYRO3 FOXP3 FOXP3 HLX HLX CD74 CD74 PIR PIR ITGB6 ITGB6 RHOA RHOA LCK LCK PTPN2 PTPN2 CD79A CD79A CLEC4E CLEC4E ENSCHIP00000011371 ENSCHIP00000011371 YY1 YY1 ENSCHIP00000011351 ENSCHIP00000011351 SOX4 SOX4 RAG1 RAG1 IL7 IL7 TP53 TP53 ZFP36L2 ZFP36L2 DOCK11 DOCK11 SLAMF6 SLAMF6 EOMES EOMES TOX TOX CD28 CD28 IL15 IL15 SP3 SP3 GIMAP1 GIMAP1 TUSC2 TUSC2 LOC102179668 LOC102179668 MED1 MED1 MERTK MERTK PTGER4 PTGER4 SHH SHH ZNF683 ZNF683 PPP3CB PPP3CB LOC102183503 LOC102183503 LOC108634973 LOC108634973 GIMAP5 GIMAP5 LIG4 LIG4 FZD9 FZD9 LOC108635164 LOC108635164 LOC108636617 LOC108636617 LOC108635529 LOC108635529 LOC108636634 LOC108636634 LOC102180392 LOC102180392 PSMB11 PSMB11 LOC108633243 LOC108633243 RC3H1 RC3H1 LRRC8A LRRC8A JUN JUN TNFSF13B TNFSF13B GPS2 GPS2 LOC108636616 LOC108636616 LOC102179943 LOC102179943 FLT3 FLT3 IL2RG IL2RG CD3D CD3D RHOH RHOH FZD5 FZD5 EZH2 EZH2 DCAF1 DCAF1 ENSCHIP00000003765 ENSCHIP00000003765
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IFNEInterferon epsilon. (193 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (209 aa)
LOC108636544Uncharacterized protein. (186 aa)
LOC108634604Uncharacterized protein. (195 aa)
CEBPGCCAAT enhancer binding protein gamma. (149 aa)
CTSVUncharacterized protein; Belongs to the peptidase C1 family. (334 aa)
LOC108636623Uncharacterized protein. (195 aa)
MFNGBeta-1,3-N-acetylglucosaminyltransferase. (320 aa)
GATA1GATA binding protein 1. (413 aa)
IFNAUncharacterized protein. (189 aa)
RAG2Recombination activating 2. (527 aa)
ENSCHIP00000005136JmjC domain-containing protein. (236 aa)
BATFBasic leucine zipper ATF-like transcription factor. (125 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (214 aa)
NFIL3Nuclear factor interleukin-3-regulated protein; Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts. Represses transcriptional activity of PER1. Represses transcriptional activity of PER2 via the B-site on the promoter. Activates transcription from the interleukin-3 promoter in T- cells. Competes for the same consensus-binding site with PAR DNA- bi [...] (462 aa)
LOC102174842Uncharacterized protein. (189 aa)
SLAMF1Ig-like domain-containing protein. (338 aa)
ENSCHIP00000005465Uncharacterized protein. (168 aa)
ENSCHIP00000005590AIG1-type G domain-containing protein. (278 aa)
LOC108636628Uncharacterized protein. (195 aa)
NCAPH2Non-SMC condensin II complex subunit H2. (617 aa)
GPR68G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (371 aa)
IL18R1Interleukin 18 receptor 1. (538 aa)
LOC108635000Uncharacterized protein. (195 aa)
LOC108636627Uncharacterized protein. (189 aa)
NRARPNOTCH regulated ankyrin repeat protein. (114 aa)
FUT7Fucosyltransferase 7. (342 aa)
LOC108636629Uncharacterized protein. (186 aa)
PLCL2Phosphoinositide phospholipase C. (1118 aa)
LOC108636626Uncharacterized protein. (195 aa)
LOC102181867Uncharacterized protein. (186 aa)
CD4CD4 molecule. (455 aa)
ENTPD7Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (604 aa)
ADGRG3Adhesion G protein-coupled receptor G3; Belongs to the G-protein coupled receptor 2 family. (547 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
LOC102180761Uncharacterized protein. (189 aa)
ENSCHIP00000007820Uncharacterized protein. (173 aa)
VAV1Vav guanine nucleotide exchange factor 1. (844 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (550 aa)
CLEC4DC-type lectin domain family 4 member D. (212 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
IRF2BP2Interferon regulatory factor 2 binding protein 2. (588 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2993 aa)
LOC102189208Uncharacterized protein. (168 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (464 aa)
TMEM176BTransmembrane protein 176B. (265 aa)
SRFSerum response factor. (509 aa)
SYKSpleen associated tyrosine kinase. (636 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (237 aa)
LOC108636632Uncharacterized protein. (186 aa)
ZAP70Tyrosine-protein kinase. (622 aa)
CDH17Cadherin 17. (832 aa)
IL6RInterleukin 6 receptor. (441 aa)
CD3ECD3e molecule. (194 aa)
RELBRELB proto-oncogene, NF-kB subunit. (645 aa)
LOC108636620Uncharacterized protein. (195 aa)
GPR183G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (356 aa)
IL31RAInterleukin 31 receptor A. (714 aa)
ENSCHIP00000010278Uncharacterized protein; Belongs to the pirin family. (255 aa)
SOX13SRY-box transcription factor 13. (592 aa)
LOC108635823AIG1-type G domain-containing protein. (297 aa)
LOC102181595Uncharacterized protein. (186 aa)
MAFBMAF bZIP transcription factor B. (329 aa)
CSF2Granulocyte-macrophage colony stimulating factor. (144 aa)
ZBTB46Zinc finger and BTB domain containing 46. (589 aa)
IRF8Interferon regulatory factor 8. (426 aa)
TCF7Transcription factor 7. (418 aa)
PDE1BPhosphodiesterase. (535 aa)
LYL1LYL1 basic helix-loop-helix family member. (281 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (554 aa)
ADAAdenosine deaminase. (400 aa)
TMEM98Transmembrane protein 98. (226 aa)
ENSCHIP00000033427Uncharacterized protein. (262 aa)
CD8ACD8a molecule. (233 aa)
ARMC5Armadillo repeat containing 5. (939 aa)
THOC5THO complex 5. (694 aa)
BCL6BCL6 transcription repressor. (706 aa)
F2RL1F2R like trypsin receptor 1. (397 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (579 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
GBAGlucosylceramidase. (536 aa)
ERBB2Receptor protein-tyrosine kinase. (1250 aa)
ZBTB7BZinc finger and BTB domain containing 7B. (539 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa)
RORAUncharacterized protein. (527 aa)
PRR7Proline rich 7, synaptic. (270 aa)
MR1Major histocompatibility complex, class I-related; Belongs to the MHC class I family. (336 aa)
STAT6Signal transducer and activator of transcription. (841 aa)
FBXO7F-box protein 7. (523 aa)
ENSCHIP00000031025Uncharacterized protein. (171 aa)
CTNNB1Catenin beta 1. (781 aa)
POU2F2POU domain protein. (479 aa)
CCR6C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (375 aa)
LEF1HMG box domain-containing protein. (430 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (475 aa)
PAX1Paired box 1. (443 aa)
YY1AP1Uncharacterized protein. (667 aa)
CLEC4GC-type lectin domain family 4 member G. (291 aa)
ENSCHIP00000030196Uncharacterized protein. (144 aa)
GATA3GATA binding protein 3. (467 aa)
ENSCHIP00000027739Uncharacterized protein. (501 aa)
CD19CD19 molecule. (561 aa)
LEPRLeptin receptor. (1166 aa)
NTRK1Tyrosine-protein kinase receptor. (821 aa)
BLKTyrosine-protein kinase. (501 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (157 aa)
LFNGBeta-1,3-N-acetylglucosaminyltransferase. (380 aa)
LTBRUncharacterized protein. (428 aa)
GPR18G protein-coupled receptor 18; Belongs to the G-protein coupled receptor 1 family. (330 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (762 aa)
ZFP36L1ZFP36 ring finger protein like 1. (338 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (602 aa)
NOTCH2Notch receptor 2. (2471 aa)
DOCK2DHR-1 domain-containing protein; Belongs to the DOCK family. (846 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1067 aa)
LYNTyrosine-protein kinase. (512 aa)
KITMast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] (974 aa)
STAT5ASignal transducer and activator of transcription. (810 aa)
CMTM7CKLF like MARVEL transmembrane domain containing 7. (174 aa)
JMJD6JmjC domain-containing protein. (414 aa)
TBX21T-box transcription factor 21. (533 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (829 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (946 aa)
RSAD2Radical S-adenosyl methionine domain containing 2. (364 aa)
ST3GAL1ST3 beta-galactoside alpha-2,3-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (339 aa)
STAT5BSignal transducer and activator of transcription. (808 aa)
GON4LMyb-like domain-containing protein. (2211 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (442 aa)
ABL1Tyrosine-protein kinase. (1151 aa)
BATF2Basic leucine zipper ATF-like transcription factor 2. (275 aa)
BTKTyrosine-protein kinase. (658 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
DCSTAMPDendrocyte expressed seven transmembrane protein. (510 aa)
LOC102178618AIG1-type G domain-containing protein. (214 aa)
FNIP1Folliculin interacting protein 1. (1162 aa)
CARD11Caspase recruitment domain family member 11. (1154 aa)
ANXA1Annexin. (346 aa)
IL7RInterleukin 7 receptor. (459 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (724 aa)
CBFBCore-binding factor subunit beta. (187 aa)
SASH3SAM and SH3 domain containing 3. (380 aa)
ENSCHIP00000022485AIG1-type G domain-containing protein. (295 aa)
AXLAXL receptor tyrosine kinase. (887 aa)
FOXN1Forkhead box N1. (645 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
ZBTB1Zinc finger and BTB domain containing 1. (644 aa)
PATZ1POZ/BTB and AT hook containing zinc finger 1. (687 aa)
LOC106502311Uncharacterized protein. (148 aa)
TNFSF8TNF superfamily member 8; Belongs to the tumor necrosis factor family. (234 aa)
POU2AF1POU class 2 homeobox associating factor 1. (263 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
IRF1Interferon regulatory factor. (322 aa)
THEMISThymocyte selection associated. (641 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (905 aa)
PKNOX1PBX/knotted 1 homeobox 1. (436 aa)
SPI1Spi-1 proto-oncogene. (270 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1986 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (192 aa)
TRAF3IP2TRAF3 interacting protein 2. (572 aa)
ENSCHIP00000021158Uncharacterized protein. (182 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (772 aa)
LOC108635503Uncharacterized protein. (195 aa)
ITFG2Integrin alpha FG-GAP repeat containing 2. (444 aa)
BATF3Basic leucine zipper ATF-like transcription factor 3. (122 aa)
LOC108635454Uncharacterized protein. (195 aa)
RC3H2Ring finger and CCCH-type domains 2. (1189 aa)
LOC108635455Uncharacterized protein. (195 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (135 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (379 aa)
LOC108633160Uncharacterized protein. (189 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
IKZF1IKAROS family zinc finger 1. (519 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (817 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (537 aa)
FASNFatty acid synthase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities as an acyl carrier protein. (2755 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (774 aa)
CCL19C-C motif chemokine. (102 aa)
ONECUT1One cut domain family member. (464 aa)
TSC1Uncharacterized protein. (1158 aa)
ENSCHIP00000019035Uncharacterized protein. (191 aa)
HECTD1HECT domain E3 ubiquitin protein ligase 1. (2610 aa)
CRACR2ACalcium release activated channel regulator 2A. (723 aa)
LOC106503900AIG1-type G domain-containing protein. (294 aa)
LOC102188370Uncharacterized protein. (455 aa)
EP300E1A binding protein p300. (2411 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1491 aa)
NKX2-3NK2 homeobox 3. (367 aa)
CD83CD83 molecule. (199 aa)
AIREAutoimmune regulator. (548 aa)
LOC102178162AIG1-type G domain-containing protein. (302 aa)
RABL3RAB, member of RAS oncogene family like 3. (236 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1278 aa)
CLCF1Cardiotrophin like cytokine factor 1. (220 aa)
IRF4Interferon regulatory factor 4. (450 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. (331 aa)
AZI25-azacytidine induced 2. (406 aa)
CD79BCD79b molecule. (221 aa)
MALT1MALT1 paracaspase. (830 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3058 aa)
RIPK3Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (243 aa)
IFNKInterferon kappa. (205 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (942 aa)
BCL2BH4_2 domain-containing protein. (229 aa)
BCL3BCL3 transcription coactivator. (454 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
TPD52Uncharacterized protein. (238 aa)
RUNX2RUNX family transcription factor 2. (585 aa)
LY9Ig-like domain-containing protein. (511 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (573 aa)
ENSCHIP00000015111Uncharacterized protein. (97 aa)
RAB44RAB44, member RAS oncogene family. (976 aa)
ENSCHIP00000015031Uncharacterized protein. (173 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1069 aa)
DCLRE1CDNA cross-link repair 1C. (710 aa)
GAS6Growth arrest specific 6. (671 aa)
LMBR1LLimb development membrane protein 1 like; Belongs to the LIMR family. (492 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (701 aa)
FCER1GFc fragment of IgE receptor Ig. (76 aa)
GLI3GLI family zinc finger 3. (1614 aa)
NHEJ1Non-homologous end joining factor 1. (299 aa)
PREX1Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1653 aa)
CCR9C-C motif chemokine receptor 9; Belongs to the G-protein coupled receptor 1 family. (367 aa)
LGALS1Galectin-1; Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. Has hemaglutinating activity towards human erythrocytes. (136 aa)
ENSCHIP00000012937Uncharacterized protein. (188 aa)
MS4A1Membrane spanning 4-domains A1. (297 aa)
PRTN3Proteinase 3; Belongs to the peptidase S1 family. (256 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (795 aa)
IKZF3IKAROS family zinc finger 3. (509 aa)
TYRO3TYRO3 protein tyrosine kinase. (889 aa)
FOXP3Forkhead box P3. (463 aa)
HLXH2.0 like homeobox. (488 aa)
CD74CD74 molecule. (261 aa)
PIRUncharacterized protein; Belongs to the pirin family. (289 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (844 aa)
RHOARas-like protein family member A. (193 aa)
LCKTyrosine-protein kinase. (509 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (417 aa)
CD79ACD79a molecule. (223 aa)
CLEC4EC-type lectin domain family 4 member E. (212 aa)
ENSCHIP00000011371Uncharacterized protein. (193 aa)
YY1YY1 transcription factor. (415 aa)
ENSCHIP00000011351Uncharacterized protein. (171 aa)
SOX4SRY-box transcription factor 4. (504 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa)
IL7Interleukin 7. (181 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa)
ZFP36L2ZFP36 ring finger protein like 2. (490 aa)
DOCK11Dedicator of cytokinesis 11; Belongs to the DOCK family. (2087 aa)
SLAMF6Ig-like domain-containing protein. (351 aa)
EOMESEomesodermin. (701 aa)
TOXThymocyte selection associated high mobility group box. (527 aa)
CD28CD28 molecule. (228 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (161 aa)
SP3Sp3 transcription factor. (778 aa)
GIMAP1AIG1-type G domain-containing protein. (302 aa)
TUSC2Uncharacterized protein. (110 aa)
LOC102179668Uncharacterized protein. (191 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1577 aa)
MERTKMER proto-oncogene, tyrosine kinase. (992 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (513 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
ZNF683Uncharacterized protein. (489 aa)
PPP3CBSerine/threonine-protein phosphatase. (535 aa)
LOC102183503AIG1-type G domain-containing protein. (309 aa)
LOC108634973Uncharacterized protein. (195 aa)
GIMAP5AIG1-type G domain-containing protein. (298 aa)
LIG4DNA ligase. (911 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (589 aa)
LOC108635164AIG1-type G domain-containing protein. (314 aa)
LOC108636617Uncharacterized protein. (195 aa)
LOC108635529Uncharacterized protein. (189 aa)
LOC108636634Uncharacterized protein. (186 aa)
LOC102180392Uncharacterized protein. (195 aa)
PSMB11Proteasome subunit beta 11. (336 aa)
LOC108633243Uncharacterized protein. (186 aa)
RC3H1Ring finger and CCCH-type domains 1. (1123 aa)
LRRC8ALeucine rich repeat containing 8 VRAC subunit A. (810 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (335 aa)
TNFSF13BTumor necrosis factor superfamily member 13b; Belongs to the tumor necrosis factor family. (280 aa)
GPS2G protein pathway suppressor 2. (327 aa)
LOC108636616Uncharacterized protein. (195 aa)
LOC102179943Uncharacterized protein. (189 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (992 aa)
IL2RGFibronectin type-III domain-containing protein. (378 aa)
CD3DCD3d molecule. (167 aa)
RHOHRas homolog family member H. (191 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa)
DCAF1DDB1 and CUL4 associated factor 1. (1507 aa)
ENSCHIP00000003765AIG1-type G domain-containing protein. (277 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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