STRINGSTRING
CX3CR1 CX3CR1 CDON CDON DRD2 DRD2 FZD9 FZD9 ADGRG1 ADGRG1 DISC1 DISC1 LRP2 LRP2 OTP OTP FGF2 FGF2 WNT3A WNT3A HIF1A HIF1A CIP2A CIP2A DLL4 DLL4 GLI3 GLI3 ELL3 ELL3 DMRTA2 DMRTA2 SOX10 SOX10 NR2E1 NR2E1 PROX1 PROX1 LHX1 LHX1 ZNF335 ZNF335 DISP3 DISP3 FOXG1 FOXG1 LHX5 LHX5 SMO SMO PAX6 PAX6 FZD3 FZD3 SHH SHH TOX TOX LHX2 LHX2 SMARCD3 SMARCD3 CTNNB1 CTNNB1 ZNF423 ZNF423 ASCL1 ASCL1 ITGB1 ITGB1 GPR37L1 GPR37L1 KDM1A KDM1A DCT DCT GLI1 GLI1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (358 aa)
CDONCell adhesion associated, oncogene regulated. (1254 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (589 aa)
ADGRG1Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (686 aa)
DISC1DISC1 scaffold protein. (851 aa)
LRP2LDL receptor related protein 2. (4649 aa)
OTPOrthopedia homeobox. (325 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa)
HIF1AUncharacterized protein. (823 aa)
CIP2ACell proliferation regulating inhibitor of protein phosphatase 2A. (892 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (701 aa)
GLI3GLI family zinc finger 3. (1614 aa)
ELL3Elongation factor for RNA polymerase II 3. (395 aa)
DMRTA2DMRT like family A2. (535 aa)
SOX10SRY-box transcription factor 10. (469 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (385 aa)
PROX1Prospero homeobox 1. (734 aa)
LHX1LIM homeobox 1. (406 aa)
ZNF335Zinc finger protein 335. (1345 aa)
DISP3Dispatched RND transporter family member 3. (1392 aa)
FOXG1Forkhead box G1. (538 aa)
LHX5LIM homeobox 5. (402 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (780 aa)
PAX6Paired box 6. (486 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
TOXThymocyte selection associated high mobility group box. (527 aa)
LHX2Uncharacterized protein. (422 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (483 aa)
CTNNB1Catenin beta 1. (781 aa)
ZNF423Zinc finger protein 423. (1308 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (219 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
GPR37L1G protein-coupled receptor 37 like 1. (478 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (873 aa)
DCTDopachrome tautomerase. (517 aa)
GLI1GLI family zinc finger 1. (1105 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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