STRINGSTRING
GJA1 GJA1 PLAT PLAT LOC102176379 LOC102176379 NODAL NODAL PRSS37 PRSS37 LOC100861170 LOC100861170 RNASE10 RNASE10 TPPP2 TPPP2 STK4 STK4 TEX101 TEX101 FANCA FANCA GPR149 GPR149 TACR1-2 TACR1-2 LOC106502686 LOC106502686 UNC5C UNC5C FBXO43 FBXO43 NPR2 NPR2 PRDM14 PRDM14 CCDC36 CCDC36 LOC102170441 LOC102170441 BMP7 BMP7 HOXD13 HOXD13 TIMP1 TIMP1 TTK TTK AGO2 AGO2 LOC102187271 LOC102187271 NKX3-1 NKX3-1 CIB1 CIB1 CCDC87 CCDC87 STK3 STK3 HORMAD1 HORMAD1 YBX3 YBX3 ZP2 ZP2 ENSCHIP00000007700 ENSCHIP00000007700 PHLDA2 PHLDA2 MEIOC MEIOC GPR3 GPR3 ENSCHIP00000007999 ENSCHIP00000007999 PLA2G10 PLA2G10 ENSCHIP00000008487 ENSCHIP00000008487 MOS MOS ARHGDIB ARHGDIB LOC102171580 LOC102171580 FAM170B FAM170B IQCF1 IQCF1 NANOS2 NANOS2 PTGDR2 PTGDR2 ACVR1C ACVR1C SYCP2 SYCP2 ESR1 ESR1 MSX1 MSX1 RAD51AP1 RAD51AP1 LIF LIF LHFPL2 LHFPL2 PAEP PAEP SFRP1 SFRP1 SNAI1 SNAI1 SOD1 SOD1 LOC102177044 LOC102177044 FZR1 FZR1 DDB1 DDB1 RAD1 RAD1 VIP VIP CDC25B CDC25B ZFPM2 ZFPM2 CDKN1B CDKN1B UMODL1 UMODL1 STRA8 STRA8 WNT5A WNT5A GNRH1 GNRH1 FBXO42 FBXO42 HYAL3 HYAL3 OVOL1 OVOL1 EFCAB1 EFCAB1 GLRA1 GLRA1 NUPR1 NUPR1 ENSCHIP00000017929 ENSCHIP00000017929 UBE2B UBE2B ITGB3 ITGB3 GCM1 GCM1 CACNA1H CACNA1H TCP11 TCP11 STXBP1 STXBP1 ACVR1B ACVR1B WEE2 WEE2 LOC108638072 LOC108638072 PSMA8 PSMA8 IGF1 IGF1 DHX37 DHX37 ENSCHIP00000020647 ENSCHIP00000020647 LOC102185508 LOC102185508 MYH9 MYH9 BNC1 BNC1 SIRT2 SIRT2 NR5A1 NR5A1 CDC20 CDC20 CFAP206 CFAP206 TACR3 TACR3 FGF9 FGF9 JAG1 JAG1 BMP4 BMP4 NOTCH1 NOTCH1 CHFR CHFR ANKRD31 ANKRD31 SYCE3 SYCE3 ENSCHIP00000024162 ENSCHIP00000024162 AR AR LOC100861169 LOC100861169 TACR1 TACR1 SOX9 SOX9 STK11 STK11 ZP3 ZP3 TACR2 TACR2 CFAP69 CFAP69 MAPK15 MAPK15 TRIP13 TRIP13 KIT KIT PRDX4 PRDX4 NLRP5 NLRP5 PIWIL2 PIWIL2 YTHDF2 YTHDF2 WDR77 WDR77 LFNG LFNG CALR CALR SHH SHH LOC102184249 LOC102184249 CDC25A CDC25A IQCF5 IQCF5 OOEP OOEP DMRT1 DMRT1 AMH AMH SYDE1 SYDE1 INHBB INHBB AURKA AURKA APELA APELA CDC25C CDC25C ENSCHIP00000029704 ENSCHIP00000029704 ASTL ASTL ENSCHIP00000030308 ENSCHIP00000030308 MAEL MAEL SHB SHB CCR6 CCR6 CTNNB1 CTNNB1 PDE3A PDE3A INHBA INHBA ENSCHIP00000031746 ENSCHIP00000031746 NPM2 NPM2 EAF2 EAF2 ZP4 ZP4 SERPINF1 SERPINF1 YTHDF3 YTHDF3 B4GALT1 B4GALT1 FBXO5 FBXO5 SULF1 SULF1 SPINK1 SPINK1 SPATA22 SPATA22 SMURF2 SMURF2 CNTD1 CNTD1 ADA ADA ZNF112 ZNF112 C1QBP C1QBP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (565 aa)
LOC102176379Wee1-like protein kinase. (549 aa)
NODALNodal growth differentiation factor. (346 aa)
PRSS37Serine protease 37. (235 aa)
LOC100861170Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. (64 aa)
RNASE10Ribonuclease A family member 10 (inactive); Belongs to the pancreatic ribonuclease family. (213 aa)
TPPP2Tubulin polymerization promoting protein family member 2. (171 aa)
STK4Serine/threonine kinase 4. (487 aa)
TEX101UPAR/Ly6 domain-containing protein. (253 aa)
FANCAFA complementation group A. (1416 aa)
GPR149G protein-coupled receptor 149. (737 aa)
TACR1-2G_PROTEIN_RECEP_F1_2 domain-containing protein. (130 aa)
LOC106502686Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (191 aa)
UNC5CUnc-5 netrin receptor C. (914 aa)
FBXO43F-box protein 43. (680 aa)
NPR2Guanylate cyclase. (1047 aa)
PRDM14PR/SET domain 14. (571 aa)
CCDC36Coiled-coil domain containing 36. (599 aa)
LOC102170441Uncharacterized protein. (419 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
HOXD13Homeobox D13. (340 aa)
TIMP1NTR domain-containing protein. (207 aa)
TTKTTK protein kinase. (852 aa)
AGO2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (860 aa)
LOC102187271Rhodanese domain-containing protein. (506 aa)
NKX3-1NK3 homeobox 1. (239 aa)
CIB1Calcium and integrin binding 1. (191 aa)
CCDC87Coiled-coil domain containing 87. (857 aa)
STK3Serine/threonine kinase 3. (495 aa)
HORMAD1HORMA domain containing 1. (377 aa)
YBX3Y-box binding protein 3. (376 aa)
ZP2Zona pellucida glycoprotein 2. (708 aa)
ENSCHIP00000007700Uncharacterized protein. (385 aa)
PHLDA2Pleckstrin homology like domain family A member 2. (128 aa)
MEIOCMeiosis specific with coiled-coil domain. (960 aa)
GPR3G protein-coupled receptor 3; Belongs to the G-protein coupled receptor 1 family. (330 aa)
ENSCHIP00000007999Uncharacterized protein. (233 aa)
PLA2G10Phospholipase A(2). (158 aa)
ENSCHIP00000008487Uncharacterized protein. (123 aa)
MOSMOS proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily. (340 aa)
ARHGDIBRho GDP dissociation inhibitor beta. (200 aa)
LOC102171580Uncharacterized protein. (511 aa)
FAM170BFamily with sequence similarity 170 member B. (289 aa)
IQCF1IQ motif containing F1. (203 aa)
NANOS2Nanos C2HC-type zinc finger 2; Belongs to the nanos family. (138 aa)
PTGDR2Prostaglandin D2 receptor 2; Belongs to the G-protein coupled receptor 1 family. (395 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
SYCP2Synaptonemal complex protein 2. (1456 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (596 aa)
MSX1Msh homeobox 1. (303 aa)
RAD51AP1RAD51 associated protein 1. (326 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
LHFPL2LHFPL tetraspan subfamily member 2. (228 aa)
PAEPBeta-lactoglobulin; Primary component of whey, it binds retinol and is probably involved in the transport of that molecule; Belongs to the calycin superfamily. Lipocalin family. (219 aa)
SFRP1Secreted frizzled related protein 1. (308 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
LOC102177044Uncharacterized protein. (857 aa)
FZR1Fizzy and cell division cycle 20 related 1. (513 aa)
DDB1Damage specific DNA binding protein 1. (1140 aa)
RAD1Uncharacterized protein. (279 aa)
VIPVasoactive intestinal peptide. (170 aa)
CDC25BRhodanese domain-containing protein. (564 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1022 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
UMODL1ZP domain-containing protein. (395 aa)
STRA8Stimulated by retinoic acid 8. (447 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
GNRH1Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (92 aa)
FBXO42F-box protein 42. (717 aa)
HYAL3Hyaluronidase. (419 aa)
OVOL1Ovo like transcriptional repressor 1. (267 aa)
EFCAB1EF-hand calcium binding domain 1. (212 aa)
GLRA1Glycine receptor alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (451 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (82 aa)
ENSCHIP00000017929Uncharacterized protein. (84 aa)
UBE2BUbiquitin conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (786 aa)
GCM1Glial cells missing transcription factor 1. (427 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (1453 aa)
TCP11T-complex 11. (507 aa)
STXBP1Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (594 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
WEE2Wee1-like protein kinase. (566 aa)
LOC108638072Uncharacterized protein. (152 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
IGF1Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (188 aa)
DHX37DEAH-box helicase 37. (1163 aa)
ENSCHIP00000020647Uncharacterized protein. (142 aa)
LOC102185508Uncharacterized protein. (698 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1986 aa)
BNC1Basonuclin 1. (963 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (390 aa)
NR5A1Nuclear receptor subfamily 5 group A member 1. (461 aa)
CDC20WD_REPEATS_REGION domain-containing protein. (499 aa)
CFAP206Uncharacterized protein. (622 aa)
TACR3Tachykinin receptor 3; Belongs to the G-protein coupled receptor 1 family. (539 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
NOTCH1Notch receptor 1. (2508 aa)
CHFRCheckpoint with forkhead and ring finger domains. (662 aa)
ANKRD31ANK_REP_REGION domain-containing protein. (661 aa)
SYCE3Synaptonemal complex central element protein 3. (89 aa)
ENSCHIP00000024162Uncharacterized protein. (158 aa)
ARAndrogen receptor. (891 aa)
LOC100861169Uncharacterized protein. (73 aa)
TACR1G_PROTEIN_RECEP_F1_2 domain-containing protein. (352 aa)
SOX9SRY-box transcription factor 9. (525 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (442 aa)
ZP3ZP domain-containing protein. (432 aa)
TACR2Tachykinin receptor 2; Belongs to the G-protein coupled receptor 1 family. (387 aa)
CFAP69Cilia and flagella associated protein 69. (951 aa)
MAPK15Mitogen-activated protein kinase. (543 aa)
TRIP13Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (432 aa)
KITMast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] (974 aa)
PRDX4Peroxiredoxin 4. (275 aa)
NLRP5Uncharacterized protein. (1046 aa)
PIWIL2Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family. (967 aa)
YTHDF2YTH N6-methyladenosine RNA binding protein 2. (582 aa)
WDR77WD repeat domain 77. (342 aa)
LFNGBeta-1,3-N-acetylglucosaminyltransferase. (380 aa)
CALRCalreticulin. (417 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
LOC102184249Olfactory receptor. (313 aa)
CDC25ACell division cycle 25A. (517 aa)
IQCF5IQ motif containing F5. (182 aa)
OOEPOocyte expressed protein. (140 aa)
DMRT1Doublesex and mab-3 related transcription factor 1. (371 aa)
AMHAnti-Mullerian hormone. (575 aa)
SYDE1Synapse defective Rho GTPase homolog 1. (691 aa)
INHBBInhibin subunit beta B. (408 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (405 aa)
APELAUncharacterized protein. (54 aa)
CDC25CCell division cycle 25C. (452 aa)
ENSCHIP00000029704Uncharacterized protein. (147 aa)
ASTLMetalloendopeptidase. (423 aa)
ENSCHIP00000030308Uncharacterized protein. (155 aa)
MAELMaelstrom spermatogenic transposon silencer. (434 aa)
SHBSH2 domain-containing protein. (507 aa)
CCR6C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (375 aa)
CTNNB1Catenin beta 1. (781 aa)
PDE3APhosphodiesterase. (834 aa)
INHBAInhibin beta A subunit. (425 aa)
ENSCHIP00000031746Uncharacterized protein. (198 aa)
NPM2Nucleophosmin/nucleoplasmin 2. (197 aa)
EAF2ELL associated factor 2. (262 aa)
ZP4Zona pellucida glycoprotein 4. (531 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (416 aa)
YTHDF3YTH N6-methyladenosine RNA binding protein 3. (603 aa)
B4GALT1Beta-1,4-galactosyltransferase I. (402 aa)
FBXO5F-box protein 5. (448 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (868 aa)
SPINK1Serine peptidase inhibitor, Kazal type 1. (79 aa)
SPATA22Spermatogenesis associated 22. (364 aa)
SMURF2E3 ubiquitin-protein ligase. (741 aa)
CNTD1Cyclin N-terminal domain containing 1. (339 aa)
ADAAdenosine deaminase. (400 aa)
ZNF112Uncharacterized protein. (906 aa)
C1QBPComplement C1q binding protein. (278 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
Server load: low (20%) [HD]