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GRHL2 | Grainyhead like transcription factor 2. (622 aa) | ||||
GDF2 | Growth differentiation factor 2. (430 aa) | ||||
PARN | Poly(A)-specific ribonuclease. (638 aa) | ||||
CCT5 | Chaperonin containing TCP1 subunit 5. (541 aa) | ||||
FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa) | ||||
JADE3 | Jade family PHD finger 3. (859 aa) | ||||
PARP4 | Poly [ADP-ribose] polymerase. (1739 aa) | ||||
MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) | ||||
GINS4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa) | ||||
NAT10 | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1026 aa) | ||||
PINX1 | PIN2 (TERF1) interacting telomerase inhibitor 1. (312 aa) | ||||
ADIPOQ | C1q domain-containing protein. (283 aa) | ||||
ACVRL1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa) | ||||
PIF1 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (649 aa) | ||||
DSCC1 | Uncharacterized protein. (388 aa) | ||||
ENSCHIP00000012571 | Uncharacterized protein. (386 aa) | ||||
CCT4 | T-complex protein 1 subunit delta. (541 aa) | ||||
ANKRD1 | Ankyrin repeat domain 1. (319 aa) | ||||
STN1 | CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (370 aa) | ||||
EXOSC10 | Exosome component 10. (844 aa) | ||||
BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa) | ||||
ENSCHIP00000022338 | Uncharacterized protein. (300 aa) | ||||
LOC102170672 | T-complex protein 1 subunit delta. (529 aa) | ||||
RFC4 | Replication factor C subunit 4. (364 aa) | ||||
LOC108635607 | Uncharacterized protein. (512 aa) | ||||
LOC102175542 | Uncharacterized protein. (307 aa) | ||||
CERS1 | TLC domain-containing protein. (333 aa) | ||||
MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (396 aa) | ||||
TFDP1 | Transcription factor. (410 aa) | ||||
NVL | Nuclear VCP like. (860 aa) | ||||
MEAF6 | MYST/Esa1 associated factor 6. (201 aa) | ||||
ENSCHIP00000001595 | Uncharacterized protein. (333 aa) | ||||
PRKCQ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (711 aa) | ||||
PARP3 | Poly [ADP-ribose] polymerase. (525 aa) | ||||
CCT6A | Uncharacterized protein. (531 aa) | ||||
JADE1 | Jade family PHD finger 1. (863 aa) | ||||
PKIB | cAMP-dependent protein kinase inhibitor; Belongs to the PKI family. (79 aa) | ||||
NEK7 | NIMA related kinase 7; Belongs to the protein kinase superfamily. (302 aa) | ||||
POT1 | Protection of telomeres 1. (785 aa) | ||||
DACH1 | Dachshund family transcription factor 1. (761 aa) | ||||
HMBOX1 | Homeobox containing 1. (420 aa) | ||||
HNRNPU | Heterogeneous nuclear ribonucleoprotein U. (806 aa) | ||||
ENSCHIP00000002380 | Uncharacterized protein. (531 aa) | ||||
CDKN1A | Cyclin dependent kinase inhibitor 1A. (161 aa) | ||||
SRC | Tyrosine-protein kinase. (538 aa) | ||||
NIBAN2 | Niban apoptosis regulator 2. (744 aa) | ||||
TNKS | Poly [ADP-ribose] polymerase. (1327 aa) | ||||
CCDC174 | Coiled-coil domain containing 174. (467 aa) | ||||
WRAP53 | WD repeat containing antisense to TP53. (540 aa) | ||||
PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) | ||||
SH2B1 | SH2B adaptor protein 1. (775 aa) | ||||
PNKP | Polynucleotide kinase 3'-phosphatase. (522 aa) | ||||
LOC102174357 | Uncharacterized protein. (510 aa) | ||||
TINF2 | TERF1 interacting nuclear factor 2. (458 aa) | ||||
FGFR4 | Fibroblast growth factor receptor. (870 aa) | ||||
AURKB | Aurora kinase B; Belongs to the protein kinase superfamily. (344 aa) | ||||
CCT7 | T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (543 aa) | ||||
HNRNPD | Heterogeneous nuclear ribonucleoprotein D. (355 aa) | ||||
ENSCHIP00000025330 | Uncharacterized protein. (484 aa) | ||||
XRCC5 | X-ray repair cross complementing 5. (736 aa) | ||||
FBXO4 | F-box protein 4. (393 aa) | ||||
NOX4 | NADPH oxidase 4. (578 aa) | ||||
GINS3 | GINS complex subunit 3. (216 aa) | ||||
PRKD2 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa) | ||||
CCT3 | T-complex protein 1 subunit gamma. (545 aa) | ||||
DCP2 | Decapping mRNA 2. (423 aa) | ||||
GREM1 | Gremlin. (184 aa) | ||||
PARM1 | Prostate androgen-regulated mucin-like protein 1. (300 aa) | ||||
ENSCHIP00000006258 | Uncharacterized protein. (474 aa) | ||||
HGF | Hepatocyte growth factor; Belongs to the peptidase S1 family. (814 aa) | ||||
TEN1 | Uncharacterized protein. (123 aa) | ||||
MAP3K4 | Mitogen-activated protein kinase kinase kinase 4. (1590 aa) | ||||
NEK2 | NIMA related kinase 2. (445 aa) | ||||
RFC2 | Replication factor C subunit 2. (352 aa) | ||||
MEN1 | Menin 1. (609 aa) | ||||
MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa) | ||||
CHTF18 | Chromosome transmission fidelity factor 18. (948 aa) | ||||
MAPKAPK5 | Protein kinase domain-containing protein. (431 aa) | ||||
PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) | ||||
RFC3 | Replication factor C subunit 3. (356 aa) | ||||
TERF1 | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (436 aa) | ||||
LOC102189034 | Uncharacterized protein. (320 aa) | ||||
CTNNB1 | Catenin beta 1. (781 aa) | ||||
ACD | ACD shelterin complex subunit and telomerase recruitment factor. (458 aa) | ||||
HNRNPA1 | Uncharacterized protein. (320 aa) | ||||
DERPC | DERPC proline and glycine rich nuclear protein. (520 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa) | ||||
SMOC2 | SPARC related modular calcium binding 2. (445 aa) | ||||
CTC1 | CST telomere replication complex component 1. (1210 aa) | ||||
TERF2 | Telomeric repeat binding factor 2. (543 aa) | ||||
GINS2 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa) | ||||
LOC102185345 | Uncharacterized protein. (483 aa) | ||||
TCP1 | T-complex 1. (556 aa) | ||||
CCT2 | Chaperonin containing TCP1 subunit 2. (535 aa) | ||||
KAT7 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa) | ||||
ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3058 aa) | ||||
DKC1 | Dyskerin pseudouridine synthase 1. (506 aa) | ||||
POLG2 | DNA polymerase gamma 2, accessory subunit. (485 aa) | ||||
ENSCHIP00000018363 | Uncharacterized protein. (331 aa) |