STRINGSTRING
WNT5A WNT5A FGF8 FGF8 YAP1 YAP1 THPO THPO PDCD2 PDCD2 FGF2 FGF2 WNT1 WNT1 CITED1 CITED1 OSR2 OSR2 FGF9 FGF9 NR2E1 NR2E1 FGF10 FGF10 TBX3 TBX3 TGFB1 TGFB1 ATXN1L ATXN1L WNT10B WNT10B FGF4 FGF4 PRRX1 PRRX1 TERT TERT KDR KDR HNRNPU HNRNPU GJA1 GJA1 IRS2 IRS2 HMX2 HMX2 KAT7 KAT7 CTNNB1 CTNNB1 KITLG KITLG SOX11 SOX11 CCNE1 CCNE1 VEGFC VEGFC FERMT2 FERMT2 TP63 TP63 LTBP3 LTBP3 EPCAM EPCAM PTPRC PTPRC SOX9 SOX9 HMGA2 HMGA2 HOXA3 HOXA3 ELL3 ELL3 RUNX2 RUNX2 SHOX2 SHOX2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
YAP1Yes associated protein 1. (503 aa)
THPOThrombopoietin. (353 aa)
PDCD2Programmed cell death 2. (344 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
CITED1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (247 aa)
OSR2Odd-skipped related transciption factor 2. (276 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (385 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
TBX3T-box transcription factor 3. (749 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
ATXN1LAtaxin 1 like. (688 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
PRRX1Paired related homeobox 1. (245 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1123 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1390 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (806 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
IRS2Insulin receptor substrate 2. (1465 aa)
HMX2H6 family homeobox 2. (274 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa)
CTNNB1Catenin beta 1. (781 aa)
KITLGProcessed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity); Belongs to the SCF family. (274 aa)
SOX11Transcription factor SOX. (444 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (411 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (419 aa)
FERMT2Fermitin family member 2. (680 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (681 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1294 aa)
EPCAMEpithelial cell adhesion molecule. (314 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1067 aa)
SOX9SRY-box transcription factor 9. (525 aa)
HMGA2Uncharacterized protein. (104 aa)
HOXA3Homeobox A3. (437 aa)
ELL3Elongation factor for RNA polymerase II 3. (395 aa)
RUNX2RUNX family transcription factor 2. (585 aa)
SHOX2Short stature homeobox 2. (319 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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