STRINGSTRING
NARS1 NARS1 PSMC4 PSMC4 SRBD1 SRBD1 ENSCHIP00000016812 ENSCHIP00000016812 PSMC1 PSMC1 CSDE1 CSDE1 PSMC6 PSMC6 MRPL2 MRPL2 MCM6 MCM6 EIF5A2 EIF5A2 LOC102173932 LOC102173932 RPS28 RPS28 MCM4 MCM4 MCM9 MCM9 EXOSC3 EXOSC3 RNGTT RNGTT NARS2 NARS2 RPA2 RPA2 AIMP1 AIMP1 LOC108638223 LOC108638223 STN1 STN1 LOC102177819 LOC102177819 YBX3 YBX3 PSMC3 PSMC3 SPOUT1 SPOUT1 DIS3L DIS3L ENSCHIP00000005535 ENSCHIP00000005535 TEN1 TEN1 DHX8 DHX8 LOC102179516 LOC102179516 LOC102188312 LOC102188312 ENSCHIP00000003902 ENSCHIP00000003902 LOC102175621 LOC102175621 POLR2H POLR2H ENSCHIP00000002654 ENSCHIP00000002654 LOC102185958 LOC102185958 ENSCHIP00000002200 ENSCHIP00000002200 ENSCHIP00000001931 ENSCHIP00000001931 ENSCHIP00000001595 ENSCHIP00000001595 LOC102186417 LOC102186417 LIG4 LIG4 ENSCHIP00000000579 ENSCHIP00000000579 CCAR1 CCAR1 POLR3H POLR3H MCM2 MCM2 MCM3 MCM3 PSMC5 PSMC5 DDIAS DDIAS LIN28A LIN28A BRCA2 BRCA2 EXOSC2 EXOSC2 EIF1AX EIF1AX RMI2 RMI2 CSDC2 CSDC2 MCM10 MCM10 DIS3L2 DIS3L2 ENSCHIP00000025630 ENSCHIP00000025630 MCMDC2 MCMDC2 RPA3 RPA3 POLR2G POLR2G LIG3 LIG3 DARS2 DARS2 RPL8 RPL8 PNPT1 PNPT1 SUPT6H SUPT6H PDCD11 PDCD11 EIF5A EIF5A NABP1 NABP1 ENSCHIP00000031621 ENSCHIP00000031621 RPA1 RPA1 LIG1 LIG1 ENSCHIP00000032533 ENSCHIP00000032533 ENSCHIP00000032642 ENSCHIP00000032642 MCM7 MCM7 RPS11 RPS11 ENSCHIP00000011218 ENSCHIP00000011218 MEIOB MEIOB MCM5 MCM5 LIN28B LIN28B EIF2S1 EIF2S1 DARS1 DARS1 MRPS12 MRPS12 EIF1AD EIF1AD TTC14 TTC14 KARS1 KARS1 YBX1 YBX1 SSBP1 SSBP1 YARS1 YARS1 MCM8 MCM8 LOC102183030 LOC102183030 POT1 POT1 RPS23 RPS23 EXOSC1 EXOSC1 PSMC2 PSMC2 NABP2 NABP2 DIS3 DIS3 CARHSP1 CARHSP1 ZCCHC17 ZCCHC17 ENSCHIP00000015409 ENSCHIP00000015409 YBX2 YBX2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NARS1Asparaginyl-tRNA synthetase. (559 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
SRBD1S1 RNA binding domain 1. (1009 aa)
ENSCHIP00000016812Ribosomal_S17_N domain-containing protein. (143 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
CSDE1Cold shock domain containing E1. (844 aa)
PSMC6AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
MRPL2Mitochondrial ribosomal protein L2. (306 aa)
MCM6DNA helicase; Belongs to the MCM family. (821 aa)
EIF5A2Eukaryotic translation initiation factor 5A. (153 aa)
LOC102173932Uncharacterized protein. (521 aa)
RPS28Uncharacterized protein. (69 aa)
MCM4DNA helicase; Belongs to the MCM family. (851 aa)
MCM9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1137 aa)
EXOSC3Exosome component 3. (275 aa)
RNGTTPolynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (595 aa)
NARS2Asparaginyl-tRNA synthetase 2, mitochondrial. (477 aa)
RPA2Replication protein A2. (270 aa)
AIMP1tRNA-binding domain-containing protein. (352 aa)
LOC108638223Uncharacterized protein. (145 aa)
STN1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (370 aa)
LOC102177819Ribosomal_S17_N domain-containing protein; Belongs to the universal ribosomal protein uS17 family. (158 aa)
YBX3Y-box binding protein 3. (376 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (442 aa)
SPOUT1SPOUT domain containing methyltransferase 1. (359 aa)
DIS3LDIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (1053 aa)
ENSCHIP00000005535Uncharacterized protein. (62 aa)
TEN1Uncharacterized protein. (123 aa)
DHX8DEAH-box helicase 8. (1216 aa)
LOC102179516Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family. (143 aa)
LOC102188312tRNA-binding domain-containing protein. (320 aa)
ENSCHIP00000003902Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family. (143 aa)
LOC102175621Uncharacterized protein. (69 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
ENSCHIP00000002654Uncharacterized protein. (121 aa)
LOC102185958tRNA-binding domain-containing protein. (311 aa)
ENSCHIP00000002200Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family. (143 aa)
ENSCHIP00000001931AAA domain-containing protein. (316 aa)
ENSCHIP00000001595Uncharacterized protein. (333 aa)
LOC102186417CSD_1 domain-containing protein. (312 aa)
LIG4DNA ligase. (911 aa)
ENSCHIP00000000579S1-like domain-containing protein. (109 aa)
CCAR1Cell division cycle and apoptosis regulator 1. (1149 aa)
POLR3HRNA polymerase III subunit H. (204 aa)
MCM2DNA helicase; Belongs to the MCM family. (1061 aa)
MCM3DNA helicase; Belongs to the MCM family. (808 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
DDIASDNA damage induced apoptosis suppressor. (999 aa)
LIN28ACCHC-type domain-containing protein. (209 aa)
BRCA2BRCA2 DNA repair associated. (3405 aa)
EXOSC2Exosome component 2. (293 aa)
EIF1AXEukaryotic translation initiation factor 1A X-linked; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (144 aa)
RMI2Uncharacterized protein. (161 aa)
CSDC2Cold shock domain containing C2. (153 aa)
MCM10Minichromosome maintenance 10 replication initiation factor. (900 aa)
DIS3L2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] (882 aa)
ENSCHIP00000025630tRNA-binding domain-containing protein. (304 aa)
MCMDC2Minichromosome maintenance domain containing 2. (681 aa)
RPA3Uncharacterized protein. (121 aa)
POLR2GRNA polymerase II subunit G. (189 aa)
LIG3DNA ligase. (1004 aa)
DARS2Aspartyl-tRNA synthetase 2, mitochondrial. (652 aa)
RPL8Ribosomal_L2_C domain-containing protein. (257 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1. (761 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1726 aa)
PDCD11Programmed cell death 11. (1874 aa)
EIF5AEukaryotic translation initiation factor 5A. (154 aa)
NABP1Nucleic acid binding protein 1. (205 aa)
ENSCHIP00000031621Uncharacterized protein. (159 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (617 aa)
LIG1DNA ligase. (915 aa)
ENSCHIP00000032533CCHC-type domain-containing protein. (203 aa)
ENSCHIP00000032642CCHC-type domain-containing protein. (194 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa)
RPS11Ribosomal_S17_N domain-containing protein; Belongs to the universal ribosomal protein uS17 family. (158 aa)
ENSCHIP00000011218Uncharacterized protein. (167 aa)
MEIOBMeiosis specific with OB-fold. (467 aa)
MCM5DNA helicase; Belongs to the MCM family. (734 aa)
LIN28BLin-28 homolog B. (255 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
DARS1Aspartyl-tRNA synthetase. (501 aa)
MRPS12Mitochondrial ribosomal protein S12; Belongs to the universal ribosomal protein uS12 family. (139 aa)
EIF1ADEukaryotic translation initiation factor 1A domain containing. (166 aa)
TTC14Tetratricopeptide repeat domain 14. (772 aa)
KARS1Lysine--tRNA ligase. (623 aa)
YBX1CSD_1 domain-containing protein. (324 aa)
SSBP1Uncharacterized protein. (148 aa)
YARS1Tyrosine--tRNA ligase. (528 aa)
MCM8MCM domain-containing protein; Belongs to the MCM family. (832 aa)
LOC102183030Uncharacterized protein. (130 aa)
POT1Protection of telomeres 1. (785 aa)
RPS23Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family. (143 aa)
EXOSC1Exosome component 1. (195 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
NABP2Nucleic acid binding protein 2. (175 aa)
DIS3DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (1037 aa)
CARHSP1Calcium regulated heat stable protein 1. (147 aa)
ZCCHC17Uncharacterized protein. (241 aa)
ENSCHIP00000015409Lysine--tRNA ligase. (599 aa)
YBX2Y-box binding protein 2. (362 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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