STRINGSTRING
PLCG1 PLCG1 SUPT6H SUPT6H SHC3 SHC3 YES1 YES1 SH2B1 SH2B1 BLK BLK CSK CSK TEC TEC LYN LYN CHN2 CHN2 STAT5A STAT5A GRB10 GRB10 VAV2 VAV2 HCK HCK STAT5B STAT5B ABL1 ABL1 BTK BTK PIK3R1 PIK3R1 SHC2 SHC2 STAT4 STAT4 BMX BMX LCP2 LCP2 SH2D5 SH2D5 STAT3 STAT3 SH2D2A SH2D2A PTPN6 PTPN6 PTPN11 PTPN11 LOC102169118 LOC102169118 SH2D4B SH2D4B DAPP1 DAPP1 SOCS1 SOCS1 BCAR3 BCAR3 SOCS5 SOCS5 JAK2 JAK2 GRAP GRAP SRC SRC ZAP70 ZAP70 SH2D1A SH2D1A SOCS7 SOCS7 NCK1 NCK1 ABL2 ABL2 JAK1 JAK1 SHF SHF SHE SHE SHC1 SHC1 TXK TXK SHC4 SHC4 LCK LCK SRMS SRMS SH2D7 SH2D7 RASA1 RASA1 ENSCHIP00000012512 ENSCHIP00000012512 PTK6 PTK6 RIN1 RIN1 SHB SHB SOCS6 SOCS6 SH2D3A SH2D3A STAT6 STAT6 GRB14 GRB14 TNS4 TNS4 STAP1 STAP1 ITK ITK SOCS2 SOCS2 TNS3 TNS3 GRB7 GRB7 MATK MATK TNS1 TNS1 INPPL1 INPPL1 GRAP2 GRAP2 CISH CISH SH2B2 SH2B2 PLCG2 PLCG2 BLNK BLNK CHN1 CHN1 INPP5D INPP5D SH2D4A SH2D4A SH2B3 SH2B3 TNS2 TNS2 FGR FGR PIK3R3 PIK3R3 RIN3 RIN3 GRB2 GRB2 STAT2 STAT2 VAV3 VAV3 FER FER HSH2D HSH2D SHD SHD SLA SLA FES FES PIK3R2 PIK3R2 CRKL CRKL FRK FRK SYK SYK SH2D1B SH2D1B SOCS3 SOCS3 VAV1 VAV1 SH3BP2 SH3BP2 SLA2 SLA2 CRK CRK SH2D6 SH2D6 STAT1 STAT1 RIN2 RIN2 NCK2 NCK2 STAP2 STAP2 SH2D3C SH2D3C SOCS4 SOCS4 FYN FYN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1296 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1726 aa)
SHC3SHC adaptor protein 3. (592 aa)
YES1Tyrosine-protein kinase. (541 aa)
SH2B1SH2B adaptor protein 1. (775 aa)
BLKTyrosine-protein kinase. (501 aa)
CSKTyrosine-protein kinase. (450 aa)
TECTyrosine-protein kinase. (632 aa)
LYNTyrosine-protein kinase. (512 aa)
CHN2Uncharacterized protein. (524 aa)
STAT5ASignal transducer and activator of transcription. (810 aa)
GRB10Growth factor receptor bound protein 10. (591 aa)
VAV2Vav guanine nucleotide exchange factor 2. (872 aa)
HCKTyrosine-protein kinase. (528 aa)
STAT5BSignal transducer and activator of transcription. (808 aa)
ABL1Tyrosine-protein kinase. (1151 aa)
BTKTyrosine-protein kinase. (658 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
SHC2Uncharacterized protein. (565 aa)
STAT4Signal transducer and activator of transcription. (797 aa)
BMXTyrosine-protein kinase. (655 aa)
LCP2Lymphocyte cytosolic protein 2. (527 aa)
SH2D5SH2 domain containing 5. (344 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
SH2D2ASH2 domain containing 2A. (420 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
LOC102169118Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (605 aa)
SH2D4BSH2 domain containing 4B. (431 aa)
DAPP1Dual adaptor of phosphotyrosine and 3-phosphoinositides 1. (280 aa)
SOCS1Suppressor of cytokine signaling 1. (219 aa)
BCAR3BCAR3 adaptor protein, NSP family member. (826 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
GRAPUncharacterized protein. (217 aa)
SRCTyrosine-protein kinase. (538 aa)
ZAP70Tyrosine-protein kinase. (622 aa)
SH2D1ASH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. (128 aa)
SOCS7Suppressor of cytokine signaling 7. (575 aa)
NCK1Cytoplasmic protein. (377 aa)
ABL2Tyrosine-protein kinase. (1182 aa)
JAK1Tyrosine-protein kinase. (1159 aa)
SHFSrc homology 2 domain containing F. (239 aa)
SHESrc homology 2 domain containing E. (511 aa)
SHC1SHC adaptor protein 1. (583 aa)
TXKTyrosine-protein kinase. (527 aa)
SHC4SHC adaptor protein 4. (630 aa)
LCKTyrosine-protein kinase. (509 aa)
SRMSTyrosine-protein kinase. (494 aa)
SH2D7SH2 domain containing 7. (468 aa)
RASA1RAS p21 protein activator 1. (1044 aa)
ENSCHIP00000012512Uncharacterized protein. (435 aa)
PTK6Tyrosine-protein kinase. (450 aa)
RIN1Ras and Rab interactor 1. (794 aa)
SHBSH2 domain-containing protein. (507 aa)
SOCS6Uncharacterized protein. (510 aa)
SH2D3ASH2 domain containing 3A. (575 aa)
STAT6Signal transducer and activator of transcription. (841 aa)
GRB14Growth factor receptor bound protein 14. (540 aa)
TNS4Tensin 4. (694 aa)
STAP1Signal transducing adaptor family member 1. (300 aa)
ITKTyrosine-protein kinase. (619 aa)
SOCS2Suppressor of cytokine signaling 2. (198 aa)
TNS3Tensin 3. (1530 aa)
GRB7Growth factor receptor bound protein 7. (532 aa)
MATKTyrosine-protein kinase. (485 aa)
TNS1Tensin 1. (1730 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1264 aa)
GRAP2GRB2 related adaptor protein 2. (318 aa)
CISHCytokine inducible SH2 containing protein. (254 aa)
SH2B2SH2B adaptor protein 2. (624 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1278 aa)
BLNKB cell linker. (384 aa)
CHN1Chimaerin; GTPase-activating protein for p21-rac. (459 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1202 aa)
SH2D4ASH2 domain containing 4A. (450 aa)
SH2B3SH2B adaptor protein 3. (550 aa)
TNS2Tensin 2. (1409 aa)
FGRTyrosine-protein kinase. (527 aa)
PIK3R3Uncharacterized protein. (461 aa)
RIN3Ras and Rab interactor 3. (1031 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
STAT2Signal transducer and activator of transcription. (851 aa)
VAV3Vav guanine nucleotide exchange factor 3. (875 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (821 aa)
HSH2DSH2 domain-containing protein. (86 aa)
SHDSrc homology 2 domain containing transforming protein D. (340 aa)
SLASrc like adaptor. (314 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (804 aa)
PIK3R2Uncharacterized protein. (724 aa)
CRKLCRK like proto-oncogene, adaptor protein. (302 aa)
FRKTyrosine-protein kinase. (515 aa)
SYKSpleen associated tyrosine kinase. (636 aa)
SH2D1BSH2 domain containing 1B. (133 aa)
SOCS3Suppressor of cytokine signaling 3. (229 aa)
VAV1Vav guanine nucleotide exchange factor 1. (844 aa)
SH3BP2SH3 domain binding protein 2. (551 aa)
SLA2Src like adaptor 2. (276 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
SH2D6SH2 domain-containing protein. (163 aa)
STAT1Signal transducer and activator of transcription. (834 aa)
RIN2Ras and Rab interactor 2. (944 aa)
NCK2Cytoplasmic protein. (376 aa)
STAP2Signal transducing adaptor family member 2. (423 aa)
SH2D3CSH2 domain containing 3C. (860 aa)
SOCS4Suppressor of cytokine signaling 4. (440 aa)
FYNTyrosine-protein kinase. (537 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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