STRINGSTRING
TYRO3 TYRO3 YES1 YES1 LOC102176379 LOC102176379 JAK2 JAK2 PDGFRA PDGFRA EPHB3 EPHB3 SRC SRC FLT3 FLT3 FRK FRK KDR KDR FGFR3 FGFR3 FYN FYN JAK3 JAK3 EPHA5 EPHA5 NTRK3 NTRK3 FGFR1 FGFR1 SYK SYK ZAP70 ZAP70 ABL2 ABL2 JAK1 JAK1 TXK TXK TIE1 TIE1 FLT4 FLT4 LCK LCK TEK TEK SRMS SRMS INSR INSR MATK MATK FGR FGR EPHA3 EPHA3 EPHA2 EPHA2 ROS1 ROS1 FER FER FES FES WEE1 WEE1 FGFR2 FGFR2 TYK2 TYK2 WEE2 WEE2 EPHB1 EPHB1 FLT1 FLT1 INSRR INSRR AXL AXL EGFR EGFR EPHA7 EPHA7 BMX BMX MUSK MUSK BTK BTK EPHA1 EPHA1 RET RET EPHB4 EPHB4 ABL1 ABL1 HCK HCK KIT KIT LYN LYN EPHA6 EPHA6 TEC TEC EPHB2 EPHB2 CSK CSK NTRK2 NTRK2 BLK BLK NTRK1 NTRK1 EPHA8 EPHA8 FGFR4 FGFR4 MERTK MERTK IGF1R IGF1R PDGFRB PDGFRB MET MET EPHA4 EPHA4 PTK6 PTK6 ROR2 ROR2 MST1R MST1R ERBB2 ERBB2 CSF1R CSF1R ITK ITK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TYRO3TYRO3 protein tyrosine kinase. (889 aa)
YES1Tyrosine-protein kinase. (541 aa)
LOC102176379Wee1-like protein kinase. (549 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1108 aa)
EPHB3EPH receptor B3. (999 aa)
SRCTyrosine-protein kinase. (538 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (992 aa)
FRKTyrosine-protein kinase. (515 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1390 aa)
FGFR3Receptor protein-tyrosine kinase. (710 aa)
FYNTyrosine-protein kinase. (537 aa)
JAK3Tyrosine-protein kinase. (1138 aa)
EPHA5EPH receptor A5. (1031 aa)
NTRK3Tyrosine-protein kinase receptor. (825 aa)
FGFR1Fibroblast growth factor receptor. (860 aa)
SYKSpleen associated tyrosine kinase. (636 aa)
ZAP70Tyrosine-protein kinase. (622 aa)
ABL2Tyrosine-protein kinase. (1182 aa)
JAK1Tyrosine-protein kinase. (1159 aa)
TXKTyrosine-protein kinase. (527 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1139 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1365 aa)
LCKTyrosine-protein kinase. (509 aa)
TEKTEK receptor tyrosine kinase. (1125 aa)
SRMSTyrosine-protein kinase. (494 aa)
INSRTyrosine-protein kinase receptor. (1365 aa)
MATKTyrosine-protein kinase. (485 aa)
FGRTyrosine-protein kinase. (527 aa)
EPHA3EPH receptor A3. (984 aa)
EPHA2EPH receptor A2. (975 aa)
ROS1Tyrosine-protein kinase receptor. (2319 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (821 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (804 aa)
WEE1Wee1-like protein kinase. (645 aa)
FGFR2Fibroblast growth factor receptor. (841 aa)
TYK2Tyrosine-protein kinase. (1186 aa)
WEE2Wee1-like protein kinase. (566 aa)
EPHB1EPH receptor B1. (984 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1337 aa)
INSRRTyrosine-protein kinase receptor. (1301 aa)
AXLAXL receptor tyrosine kinase. (887 aa)
EGFRReceptor protein-tyrosine kinase. (1208 aa)
EPHA7EPH receptor A7. (998 aa)
BMXTyrosine-protein kinase. (655 aa)
MUSKMuscle associated receptor tyrosine kinase. (869 aa)
BTKTyrosine-protein kinase. (658 aa)
EPHA1EPH receptor A1. (968 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1118 aa)
EPHB4EPH receptor B4. (993 aa)
ABL1Tyrosine-protein kinase. (1151 aa)
HCKTyrosine-protein kinase. (528 aa)
KITMast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] (974 aa)
LYNTyrosine-protein kinase. (512 aa)
EPHA6Uncharacterized protein. (808 aa)
TECTyrosine-protein kinase. (632 aa)
EPHB2EPH receptor B2. (1016 aa)
CSKTyrosine-protein kinase. (450 aa)
NTRK2Tyrosine-protein kinase receptor. (837 aa)
BLKTyrosine-protein kinase. (501 aa)
NTRK1Tyrosine-protein kinase receptor. (821 aa)
EPHA8EPH receptor A8. (1005 aa)
FGFR4Fibroblast growth factor receptor. (870 aa)
MERTKMER proto-oncogene, tyrosine kinase. (992 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1103 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1384 aa)
EPHA4EPH receptor A4. (986 aa)
PTK6Tyrosine-protein kinase. (450 aa)
ROR2Receptor protein-tyrosine kinase. (926 aa)
MST1RMacrophage stimulating 1 receptor. (1401 aa)
ERBB2Receptor protein-tyrosine kinase. (1250 aa)
CSF1RColony stimulating factor 1 receptor. (958 aa)
ITKTyrosine-protein kinase. (619 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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