42 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	RPA3	Uncharacterized protein. (121 aa)
	UBB	Ubiquitin B. (323 aa)
	CUL4B	Cullin 4B; Belongs to the cullin family. (1027 aa)
	RFC4	Replication factor C subunit 4. (364 aa)
	POLE3	CBFD_NFYB_HMF domain-containing protein. (147 aa)
	RFC1	Replication factor C subunit 1. (1143 aa)
	ENSCHIP00000021132	Ubiquitin-like domain-containing protein. (127 aa)
	RPA2	Replication protein A2. (270 aa)
	POLD1	DNA polymerase. (1115 aa)
	DTL	Denticleless E3 ubiquitin protein ligase homolog. (761 aa)
	UBE2B	Ubiquitin conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
	RFC5	Replication factor C subunit 5. (339 aa)
	ATAD5	ATPase family AAA domain containing 5. (1894 aa)
	USP1	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (782 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	UBC	Ubiquitin C. (655 aa)
	DDB1	Damage specific DNA binding protein 1. (1140 aa)
	ENSCHIP00000027691	Ubiquitin-like domain-containing protein. (116 aa)
	MEIOB	Meiosis specific with OB-fold. (467 aa)
	RCBTB1	RCC1 and BTB domain containing protein 1. (531 aa)
	RFC3	Replication factor C subunit 3. (356 aa)
	RCBTB2	RCC1 and BTB domain containing protein 2. (551 aa)
	ENSCHIP00000009219	Ubiquitin-like domain-containing protein. (108 aa)
	ENSCHIP00000009163	Uncharacterized protein. (122 aa)
	POLD4	Uncharacterized protein. (132 aa)
	POLD2	DNA polymerase delta 2, accessory subunit. (469 aa)
	WDR48	WD repeat domain 48. (678 aa)
	RFC2	Replication factor C subunit 2. (352 aa)
	RAD18	RAD18 E3 ubiquitin protein ligase. (502 aa)
	POLE	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2281 aa)
	LOC102188771	Zf-rbx1 domain-containing protein. (108 aa)
	ENSCHIP00000002654	Uncharacterized protein. (121 aa)
	ENSCHIP00000000668	Ubiquitin-like domain-containing protein. (103 aa)
	CUL4A	Cullin 4A; Belongs to the cullin family. (764 aa)
	POLD3	Uncharacterized protein. (464 aa)
	POLE4	DNA polymerase epsilon 4, accessory subunit. (131 aa)
	POLE2	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (518 aa)
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	RBX1	RING-type domain-containing protein. (108 aa)
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (617 aa)
	KXD1	KxDL motif containing 1. (176 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATAD5	CUL4A	ENSCHIP00000016824	ENSCHIP00000000333	ATPase family AAA domain containing 5.	Cullin 4A; Belongs to the cullin family.	0.456
ATAD5	CUL4B	ENSCHIP00000016824	ENSCHIP00000024785	ATPase family AAA domain containing 5.	Cullin 4B; Belongs to the cullin family.	0.456
ATAD5	DDB1	ENSCHIP00000016824	ENSCHIP00000013716	ATPase family AAA domain containing 5.	Damage specific DNA binding protein 1.	0.541
ATAD5	DTL	ENSCHIP00000016824	ENSCHIP00000018876	ATPase family AAA domain containing 5.	Denticleless E3 ubiquitin protein ligase homolog.	0.778
ATAD5	ENSCHIP00000002654	ENSCHIP00000016824	ENSCHIP00000002654	ATPase family AAA domain containing 5.	Uncharacterized protein.	0.446
ATAD5	ENSCHIP00000009163	ENSCHIP00000016824	ENSCHIP00000009163	ATPase family AAA domain containing 5.	Uncharacterized protein.	0.588
ATAD5	ENSCHIP00000021132	ENSCHIP00000016824	ENSCHIP00000021132	ATPase family AAA domain containing 5.	Ubiquitin-like domain-containing protein.	0.421
ATAD5	MEIOB	ENSCHIP00000016824	ENSCHIP00000011102	ATPase family AAA domain containing 5.	Meiosis specific with OB-fold.	0.710
ATAD5	PCNA	ENSCHIP00000016824	ENSCHIP00000015091	ATPase family AAA domain containing 5.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.953
ATAD5	POLD1	ENSCHIP00000016824	ENSCHIP00000019836	ATPase family AAA domain containing 5.	DNA polymerase.	0.748
ATAD5	POLD2	ENSCHIP00000016824	ENSCHIP00000005641	ATPase family AAA domain containing 5.	DNA polymerase delta 2, accessory subunit.	0.630
ATAD5	POLE	ENSCHIP00000016824	ENSCHIP00000003433	ATPase family AAA domain containing 5.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.824
ATAD5	POLE2	ENSCHIP00000016824	ENSCHIP00000028310	ATPase family AAA domain containing 5.	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.779
ATAD5	POLE3	ENSCHIP00000016824	ENSCHIP00000022059	ATPase family AAA domain containing 5.	CBFD_NFYB_HMF domain-containing protein.	0.637
ATAD5	POLE4	ENSCHIP00000016824	ENSCHIP00000028280	ATPase family AAA domain containing 5.	DNA polymerase epsilon 4, accessory subunit.	0.677
ATAD5	RAD18	ENSCHIP00000016824	ENSCHIP00000004104	ATPase family AAA domain containing 5.	RAD18 E3 ubiquitin protein ligase.	0.800
ATAD5	RFC1	ENSCHIP00000016824	ENSCHIP00000021706	ATPase family AAA domain containing 5.	Replication factor C subunit 1.	0.728
ATAD5	RFC2	ENSCHIP00000016824	ENSCHIP00000004939	ATPase family AAA domain containing 5.	Replication factor C subunit 2.	0.969
ATAD5	RFC3	ENSCHIP00000016824	ENSCHIP00000010064	ATPase family AAA domain containing 5.	Replication factor C subunit 3.	0.975
ATAD5	RFC4	ENSCHIP00000016824	ENSCHIP00000023106	ATPase family AAA domain containing 5.	Replication factor C subunit 4.	0.988