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ENSCHIP00000000670 | DNA_pol_B_thumb domain-containing protein. (54 aa) | ||||
POLB | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa) | ||||
ENSCHIP00000002654 | Uncharacterized protein. (121 aa) | ||||
APEX1 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (318 aa) | ||||
POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2281 aa) | ||||
VWA5B2 | Von Willebrand factor A domain containing 5B2. (1254 aa) | ||||
RFC2 | Replication factor C subunit 2. (352 aa) | ||||
FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) | ||||
POLD2 | DNA polymerase delta 2, accessory subunit. (469 aa) | ||||
POLD1 | DNA polymerase. (1115 aa) | ||||
PARP1 | Poly [ADP-ribose] polymerase. (1020 aa) | ||||
RFC5 | Replication factor C subunit 5. (339 aa) | ||||
ATAD5 | ATPase family AAA domain containing 5. (1894 aa) | ||||
PARP3 | Poly [ADP-ribose] polymerase. (525 aa) | ||||
PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) | ||||
POLD3 | Uncharacterized protein. (464 aa) | ||||
LIG1 | DNA ligase. (915 aa) | ||||
RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (617 aa) | ||||
PARP2 | Poly [ADP-ribose] polymerase. (533 aa) | ||||
POLE2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (518 aa) | ||||
POLE4 | DNA polymerase epsilon 4, accessory subunit. (131 aa) | ||||
VWA5B1 | Von Willebrand factor A domain containing 5B1. (1183 aa) | ||||
ADPRHL2 | ADP-ribosylhydrolase like 2. (368 aa) | ||||
POLD4 | Uncharacterized protein. (132 aa) | ||||
ENSCHIP00000009163 | Uncharacterized protein. (122 aa) | ||||
RCBTB2 | RCC1 and BTB domain containing protein 2. (551 aa) | ||||
RFC3 | Replication factor C subunit 3. (356 aa) | ||||
RCBTB1 | RCC1 and BTB domain containing protein 1. (531 aa) | ||||
MEIOB | Meiosis specific with OB-fold. (467 aa) | ||||
ENSCHIP00000012960 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (287 aa) | ||||
PARG | Poly(ADP-ribose) glycohydrolase. (972 aa) | ||||
VWA5A | Von Willebrand factor A domain containing 5A. (783 aa) | ||||
APEX2 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (514 aa) | ||||
RFC1 | Replication factor C subunit 1. (1143 aa) | ||||
POLE3 | CBFD_NFYB_HMF domain-containing protein. (147 aa) | ||||
RFC4 | Replication factor C subunit 4. (364 aa) | ||||
RPA3 | Uncharacterized protein. (121 aa) | ||||
RPA2 | Replication protein A2. (270 aa) |