47 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	VAV1	Vav guanine nucleotide exchange factor 1. (844 aa)
	PIK3R2	Uncharacterized protein. (724 aa)
	ENSCHIP00000003771	Uncharacterized protein. (191 aa)
	LOC102176514	Uncharacterized protein. (182 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	PIK3CG	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
	CLEC1B	C-type lectin domain family 1 member B. (226 aa)
	SYK	Spleen associated tyrosine kinase. (636 aa)
	RHOB	RhoB. (196 aa)
	MFSD6	Major facilitator superfamily domain containing 6. (799 aa)
	RHOG	Ras homolog family member G. (191 aa)
	ENSCHIP00000011371	Uncharacterized protein. (193 aa)
	CLEC9A	C-type lectin domain containing 9A. (241 aa)
	LCK	Tyrosine-protein kinase. (509 aa)
	RHOA	Ras-like protein family member A. (193 aa)
	CDC42	Uncharacterized protein. (191 aa)
	MPIG6B	Megakaryocyte and platelet inhibitory receptor G6b. (235 aa)
	PDPK1	3-phosphoinositide dependent protein kinase 1. (557 aa)
	FCER1G	Fc fragment of IgE receptor Ig. (76 aa)
	ENSCHIP00000014395	C-type lectin domain-containing protein. (247 aa)
	PIK3R3	Uncharacterized protein. (461 aa)
	VAV3	Vav guanine nucleotide exchange factor 3. (875 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1278 aa)
	SPNS1	Sphingolipid transporter 1 (putative). (528 aa)
	MFSD6L	Major facilitator superfamily domain containing 6 like. (581 aa)
	PDPN	Uncharacterized protein. (168 aa)
	LOC102169118	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (605 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
	PIK3CB	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
	ENSCHIP00000021859	Uncharacterized protein. (311 aa)
	SPNS3	Sphingolipid transporter 3 (putative). (542 aa)
	LCP2	Lymphocyte cytosolic protein 2. (527 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
	RAC3	Rac family small GTPase 3. (192 aa)
	COL1A1	Collagen type I alpha 1 chain. (1463 aa)
	PIK3R5	Phosphoinositide-3-kinase regulatory subunit 5. (898 aa)
	VAV2	Vav guanine nucleotide exchange factor 2. (872 aa)
	LYN	Tyrosine-protein kinase. (512 aa)
	CLEC1A	C-type lectin domain family 1 member A. (278 aa)
	PRDM2	PR/SET domain 2. (1700 aa)
	RAC1	Rac family small GTPase 1. (187 aa)
	RAC2	Rac family small GTPase 2. (192 aa)
	PIK3R6	Phosphoinositide-3-kinase regulatory subunit 6. (762 aa)
	LAT	Linker for activation of T cells. (246 aa)
	COL1A2	Collagen type I alpha 2 chain. (1128 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	ENSCHIP00000003771	ENSCHIP00000012064	ENSCHIP00000003771	Uncharacterized protein.	Uncharacterized protein.	0.432
CDC42	ENSCHIP00000011371	ENSCHIP00000012064	ENSCHIP00000011371	Uncharacterized protein.	Uncharacterized protein.	0.437
CDC42	FYN	ENSCHIP00000012064	ENSCHIP00000004966	Uncharacterized protein.	Tyrosine-protein kinase.	0.978
CDC42	LCK	ENSCHIP00000012064	ENSCHIP00000011857	Uncharacterized protein.	Tyrosine-protein kinase.	0.657
CDC42	LCP2	ENSCHIP00000012064	ENSCHIP00000022907	Uncharacterized protein.	Lymphocyte cytosolic protein 2.	0.421
CDC42	LYN	ENSCHIP00000012064	ENSCHIP00000025862	Uncharacterized protein.	Tyrosine-protein kinase.	0.569
CDC42	PDPK1	ENSCHIP00000012064	ENSCHIP00000014224	Uncharacterized protein.	3-phosphoinositide dependent protein kinase 1.	0.407
CDC42	PIK3CA	ENSCHIP00000012064	ENSCHIP00000015546	Uncharacterized protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.970
CDC42	PIK3CB	ENSCHIP00000012064	ENSCHIP00000021397	Uncharacterized protein.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.988
CDC42	PIK3R1	ENSCHIP00000012064	ENSCHIP00000023684	Uncharacterized protein.	Phosphoinositide-3-kinase regulatory subunit 1.	0.960
CDC42	PIK3R2	ENSCHIP00000012064	ENSCHIP00000002671	Uncharacterized protein.	Uncharacterized protein.	0.489
CDC42	PIK3R3	ENSCHIP00000012064	ENSCHIP00000014983	Uncharacterized protein.	Uncharacterized protein.	0.939
CDC42	PLCG2	ENSCHIP00000012064	ENSCHIP00000017584	Uncharacterized protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.474
CDC42	RAC1	ENSCHIP00000012064	ENSCHIP00000028359	Uncharacterized protein.	Rac family small GTPase 1.	0.684
CDC42	RAC2	ENSCHIP00000012064	ENSCHIP00000029928	Uncharacterized protein.	Rac family small GTPase 2.	0.952
CDC42	RAC3	ENSCHIP00000012064	ENSCHIP00000023885	Uncharacterized protein.	Rac family small GTPase 3.	0.966
CDC42	RHOA	ENSCHIP00000012064	ENSCHIP00000011951	Uncharacterized protein.	Ras-like protein family member A.	0.963
CDC42	RHOB	ENSCHIP00000012064	ENSCHIP00000010080	Uncharacterized protein.	RhoB.	0.463
CDC42	RHOG	ENSCHIP00000012064	ENSCHIP00000011071	Uncharacterized protein.	Ras homolog family member G.	0.447
CDC42	SYK	ENSCHIP00000012064	ENSCHIP00000009361	Uncharacterized protein.	Spleen associated tyrosine kinase.	0.499