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| | JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (335 aa) |
| | LRRC71 | Leucine rich repeat containing 71. (560 aa) |
| | TRAF2 | TNF receptor-associated factor. (497 aa) |
| | USP14 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (494 aa) |
| | LRRC74A | Leucine rich repeat containing 74A. (494 aa) |
| | ENSCHIP00000003440 | Uncharacterized protein. (94 aa) |
| | JUNB | JunB proto-oncogene, AP-1 transcription factor subunit. (347 aa) |
| | LOC102186320 | Uncharacterized protein. (479 aa) |
| | CCDC71L | Coiled-coil domain containing 71 like. (233 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (209 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | DUSP7 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (419 aa) |
| | LOC102174188 | C-type lectin domain-containing protein. (371 aa) |
| | TANK | TBD domain-containing protein. (422 aa) |
| | ELK1 | ETS transcription factor ELK1. (440 aa) |
| | FOSL2 | FOS like 2, AP-1 transcription factor subunit. (327 aa) |
| | DNM3 | Dynamin 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (859 aa) |
| | DUSP4 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa) |
| | DUSP6 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa) |
| | IRF7 | Interferon regulatory factor 7. (480 aa) |
| | CD14 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (373 aa) |
| | TICAM2 | TIR domain-containing protein. (232 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | ENSCHIP00000008753 | Uncharacterized protein. (589 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (712 aa) |
| | LRRC14 | Leucine rich repeat containing 14. (493 aa) |
| | CD180 | CD180 molecule. (661 aa) |
| | ENSCHIP00000009219 | Ubiquitin-like domain-containing protein. (108 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (718 aa) |
| | BIRC3 | Baculoviral IAP repeat containing 3. (604 aa) |
| | NKIRAS1 | NFKB inhibitor interacting Ras like 1. (192 aa) |
| | LOC108637886 | Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform. (309 aa) |
| | PTPN4 | Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (926 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (426 aa) |
| | LY96 | Lymphocyte antigen 96. (160 aa) |
| | LOC100860781 | Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (128 aa) |
| | S100A12 | Protein S100; Belongs to the S-100 family. (92 aa) |
| | FNBP4 | Formin binding protein 4. (1017 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (156 aa) |
| | AGER | Advanced glycosylation end-product specific receptor. (416 aa) |
| | TNIP2 | TNFAIP3 interacting protein 2. (429 aa) |
| | ENSCHIP00000011946 | Uncharacterized protein; Belongs to the SKP1 family. (163 aa) |
| | MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (780 aa) |
| | MAPKAPK3 | MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (384 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | ITGB2 | Integrin beta-2; Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin ITGAM/ITGB2 is also a receptor for factor X. Integrin ITGAD/ITGB2 is a receptor [...] (774 aa) |
| | MAP2K3 | Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (349 aa) |
| | ITGAM | Integrin subunit alpha M; Belongs to the integrin alpha chain family. (1152 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa) |
| | ENSCHIP00000013634 | Uncharacterized protein. (189 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (571 aa) |
| | RPS6KA1 | Ribosomal protein S6 kinase. (760 aa) |
| | SKP1 | S-phase kinase associated protein 1. (163 aa) |
| | UBC | Ubiquitin C. (655 aa) |
| | PPP4R4 | Protein phosphatase 4 regulatory subunit 4. (874 aa) |
| | PELI2 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (412 aa) |
| | KHNYN | KH and NYN domain containing. (670 aa) |
| | FBXW11 | F-box and WD repeat domain containing 11. (563 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (573 aa) |
| | MAP3K20 | Mitogen-activated protein kinase kinase kinase 20. (800 aa) |
| | ENSCHIP00000015271 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (130 aa) |
| | TONSL | Tonsoku like, DNA repair protein. (1371 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) |
| | BPI | Uncharacterized protein. (483 aa) |
| | ENSCHIP00000016054 | Uncharacterized protein; Belongs to the SKP1 family. (157 aa) |
| | RPS6KA2 | Ribosomal protein S6 kinase. (760 aa) |
| | RIPK3 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (243 aa) |
| | TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa) |
| | LOC106503728 | Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (130 aa) |
| | ATF1 | Activating transcription factor 1. (310 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (740 aa) |
| | RPS6KA5 | Ribosomal protein S6 kinase. (827 aa) |
| | BIRC2 | Baculoviral IAP repeat containing 2. (623 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1278 aa) |
| | UBE2D1 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | VRK3 | VRK serine/threonine kinase 3. (434 aa) |
| | PPP4R1 | Protein phosphatase 4 regulatory subunit 1. (922 aa) |
| | CREB5 | cAMP responsive element binding protein 5. (549 aa) |
| | NLRX1 | NLR family member X1. (973 aa) |
| | NLRC5 | NLR family CARD domain containing 5. (1868 aa) |
| | MAP3K8 | Mitogen-activated protein kinase kinase kinase 8. (468 aa) |
| | IRF3 | Interferon regulatory factor 3. (418 aa) |
| | RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1212 aa) |
| | DNM1 | Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (863 aa) |
| | SFTPD | C-type lectin domain-containing protein. (369 aa) |
| | HMGB1 | Uncharacterized protein. (215 aa) |
| | NAIP | NLR family apoptosis inhibitory protein. (1404 aa) |
| | TLR4 | TIR domain-containing protein; Belongs to the Toll-like receptor family. (841 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (537 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (417 aa) |
| | PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (590 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (488 aa) |
| | LOC102169118 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (605 aa) |
| | NOD1 | Nucleotide binding oligomerization domain containing 1. (954 aa) |
| | LRRC31 | Leucine rich repeat containing 31. (480 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa) |
| | ENSCHIP00000021132 | Ubiquitin-like domain-containing protein. (127 aa) |
| | N4BP1 | NEDD4 binding protein 1. (897 aa) |
| | PELI3 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (445 aa) |
| | LBP | Lipopolysaccharide binding protein. (481 aa) |
| | NFKB2 | Nuclear factor kappa B subunit 2. (900 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (615 aa) |
| | ENSCHIP00000022451 | TBD domain-containing protein. (430 aa) |
| | VWC2 | Von Willebrand factor C domain containing 2. (326 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | TICAM1 | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (786 aa) |
| | IRAK2 | Interleukin 1 receptor associated kinase 2. (622 aa) |
| | BPIFC | BPI fold containing family C. (508 aa) |
| | MAP2K7 | Mitogen-activated protein kinase kinase 7. (558 aa) |
| | S100B | Protein S100; Belongs to the S-100 family. (92 aa) |
| | ENSCHIP00000024230 | Serine/threonine-protein phosphatase. (303 aa) |
| | ECSIT | ECSIT signalling integrator. (431 aa) |
| | BIRC7 | Baculoviral IAP repeat containing 7. (266 aa) |
| | PELI1 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa) |
| | LOC102168428 | Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (133 aa) |
| | MAPK15 | Mitogen-activated protein kinase. (543 aa) |
| | RPS6KA3 | Ribosomal protein S6 kinase. (740 aa) |
| | LOC102168699 | Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (130 aa) |
| | TBK1 | TANK binding kinase 1. (734 aa) |
| | UBB | Ubiquitin B. (323 aa) |
| | NFKBIB | NFKB inhibitor beta. (364 aa) |
| | ENSCHIP00000027126 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (132 aa) |
| | PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha. (598 aa) |
| | ENSCHIP00000027691 | Ubiquitin-like domain-containing protein. (116 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (408 aa) |
| | LOC102168979 | Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (130 aa) |
| | DUSP3 | Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | LRRC45 | Leucine rich repeat containing 45. (671 aa) |
| | UBE2D2 | Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (344 aa) |
| | NOD2 | Uncharacterized protein. (982 aa) |
| | NLRP9 | NLR family pyrin domain containing 9. (1037 aa) |
| | LRRC34 | Leucine rich repeat containing 34. (451 aa) |
| | LOC102173207 | TMEM189_B_dmain domain-containing protein. (271 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (442 aa) |
| | MAP2K4 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (412 aa) |
| | ENSCHIP00000031302 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (155 aa) |
| | CUL1 | CULLIN_2 domain-containing protein; Belongs to the cullin family. (776 aa) |
| | ATF7 | Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (483 aa) |
| | TIRAP | TIR domain containing adaptor protein. (228 aa) |
| | LOC102180290 | USP domain-containing protein; Belongs to the peptidase C19 family. (349 aa) |
| | DNM2 | Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa) |
| | MAP3K1 | Mitogen-activated protein kinase kinase kinase 1. (1507 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | APP | Amyloid beta precursor protein. (770 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (667 aa) |
| | MAPKAPK2 | MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (410 aa) |
| | UBE2V1 | Ubiquitin conjugating enzyme E2 V1. (147 aa) |
| | NKIRAS2 | NFKB inhibitor interacting Ras like 2. (191 aa) |
| | KXD1 | KxDL motif containing 1. (176 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (396 aa) |
| | LRRC74B | Leucine rich repeat containing 74B. (374 aa) |
| | ENSCHIP00000000668 | Ubiquitin-like domain-containing protein. (103 aa) |
| | LY86 | Lymphocyte antigen 86. (159 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (350 aa) |
| | LOC102174738 | Uncharacterized protein; Belongs to the SKP1 family. (163 aa) |
| | RPS6KA4 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (752 aa) |
| | TAB3 | TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (717 aa) |
| | SARM1 | Sterile alpha and TIR motif containing 1. (728 aa) |
