STRINGSTRING
RAPGEF1 RAPGEF1 KIDINS220 KIDINS220 NKPD1 NKPD1 NTRK1 NTRK1 MAP2K1 MAP2K1 BRAF BRAF RAP1A RAP1A MAPK1 MAPK1 CRKL CRKL NGF NGF CRK CRK MAP2K2 MAP2K2 FRS2 FRS2 YWHAB YWHAB MAPK3 MAPK3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAPGEF1Rap guanine nucleotide exchange factor 1. (1077 aa)
KIDINS220Kinase D interacting substrate 220. (1762 aa)
NKPD1NTPase KAP family P-loop domain containing 1. (610 aa)
NTRK1Tyrosine-protein kinase receptor. (821 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (397 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (774 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (396 aa)
CRKLCRK like proto-oncogene, adaptor protein. (302 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (241 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (400 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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