STRINGSTRING
MTHFD2L MTHFD2L SHMT1 SHMT1 SLC25A32 SLC25A32 C1QTNF5 C1QTNF5 TSTD2 TSTD2 MTHFD1L MTHFD1L FOLR3 FOLR3 MTHFR MTHFR SLC19A1 SLC19A1 MTHFD2 MTHFD2 FOLR1 FOLR1 SLC46A1 SLC46A1 ENSCHIP00000021405 ENSCHIP00000021405 ALDH1L2 ALDH1L2 LOC102172393 LOC102172393 DHFR DHFR LOC102169668 LOC102169668 MTHFD1 MTHFD1 SHMT2 SHMT2 SLC46A3 SLC46A3 ALDH1L1 ALDH1L1 FPGS FPGS OVCA2 OVCA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MTHFD2LMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. (347 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
SLC25A32Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (317 aa)
C1QTNF5C1q and TNF related 5. (243 aa)
TSTD2Thiosulfate sulfurtransferase like domain containing 2. (513 aa)
MTHFD1LMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (975 aa)
FOLR3Folate_rec domain-containing protein. (258 aa)
MTHFRMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (655 aa)
SLC19A1Solute carrier family 19 member 1. (508 aa)
MTHFD2Uncharacterized protein. (352 aa)
FOLR1Folate_rec domain-containing protein. (251 aa)
SLC46A1Solute carrier family 46 member 1. (459 aa)
ENSCHIP00000021405DHFR domain-containing protein. (156 aa)
ALDH1L210-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (923 aa)
LOC1021723935-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (201 aa)
DHFRDHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (187 aa)
LOC102169668DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (188 aa)
MTHFD1Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (935 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (502 aa)
SLC46A3Solute carrier family 46 member 3. (461 aa)
ALDH1L110-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (899 aa)
FPGSFolylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (585 aa)
OVCA2OVCA2 serine hydrolase domain containing. (227 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.