STRINGSTRING
DUSP4 DUSP4 FOSL2 FOSL2 ELK1 ELK1 DUSP7 DUSP7 NFKB1 NFKB1 IL17F IL17F PPP2CB PPP2CB CCDC71L CCDC71L JUNB JUNB ENSCHIP00000003440 ENSCHIP00000003440 IL17RE IL17RE JUN JUN TAB3 TAB3 RPS6KA4 RPS6KA4 LOC102174738 LOC102174738 MAPK14 MAPK14 ENSCHIP00000000668 ENSCHIP00000000668 MAPK1 MAPK1 IL17C IL17C IL17RB IL17RB IKBKG IKBKG UBA52 UBA52 CREB1 CREB1 KXD1 KXD1 DUSP3 DUSP3 PPP2CA PPP2CA VRK3 VRK3 RPS6KA5 RPS6KA5 PPP4R1 PPP4R1 CREB5 CREB5 MAP3K8 MAP3K8 RELCH RELCH RIPK2 RIPK2 MAPK11 MAPK11 PPP2R5D PPP2R5D NOD1 NOD1 ENSCHIP00000021132 ENSCHIP00000021132 PPP2R1B PPP2R1B TAB2 TAB2 IRAK2 IRAK2 MAP2K7 MAP2K7 ENSCHIP00000024230 ENSCHIP00000024230 IL17A IL17A MAPK15 MAPK15 RPS6KA3 RPS6KA3 UBB UBB ENSCHIP00000027126 ENSCHIP00000027126 PPP2R1A PPP2R1A ENSCHIP00000027691 ENSCHIP00000027691 CUL1 CUL1 ENSCHIP00000031302 ENSCHIP00000031302 MAP2K4 MAP2K4 MAPK8 MAPK8 FOS FOS NOD2 NOD2 MAP2K6 MAP2K6 ATF7 ATF7 MAPKAPK2 MAPKAPK2 UBE2V1 UBE2V1 CHUK CHUK IL25 IL25 ATF1 ATF1 RPS6KA2 RPS6KA2 ENSCHIP00000016054 ENSCHIP00000016054 MAPK3 MAPK3 MAP3K20 MAP3K20 TRAF6 TRAF6 FBXW11 FBXW11 PPP4R4 PPP4R4 UBC UBC SKP1 SKP1 RPS6KA1 RPS6KA1 TAB1 TAB1 IL17RA IL17RA IKBKB IKBKB MAP2K3 MAP2K3 MAPK9 MAPK9 MAPKAPK3 MAPKAPK3 MAPK7 MAPK7 ENSCHIP00000011946 ENSCHIP00000011946 TNIP2 TNIP2 RPS27A RPS27A FNBP4 FNBP4 MAPK10 MAPK10 LOC108637886 LOC108637886 IRAK1 IRAK1 ENSCHIP00000009219 ENSCHIP00000009219 MAP3K7 MAP3K7 ENSCHIP00000008753 ENSCHIP00000008753 ATF2 ATF2 DUSP6 DUSP6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DUSP4Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa)
FOSL2FOS like 2, AP-1 transcription factor subunit. (327 aa)
ELK1ETS transcription factor ELK1. (440 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (419 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
IL17FUncharacterized protein. (178 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
CCDC71LCoiled-coil domain containing 71 like. (233 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
ENSCHIP00000003440Uncharacterized protein. (94 aa)
IL17REInterleukin 17 receptor E. (621 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (335 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (717 aa)
RPS6KA4Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (752 aa)
LOC102174738Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
MAPK14Mitogen-activated protein kinase. (350 aa)
ENSCHIP00000000668Ubiquitin-like domain-containing protein. (103 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (396 aa)
IL17CInterleukin 17C. (178 aa)
IL17RBInterleukin 17 receptor B. (497 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (408 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
KXD1KxDL motif containing 1. (176 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
VRK3VRK serine/threonine kinase 3. (434 aa)
RPS6KA5Ribosomal protein S6 kinase. (827 aa)
PPP4R1Protein phosphatase 4 regulatory subunit 1. (922 aa)
CREB5cAMP responsive element binding protein 5. (549 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (468 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1212 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (537 aa)
MAPK11Mitogen-activated protein kinase. (417 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (590 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (954 aa)
ENSCHIP00000021132Ubiquitin-like domain-containing protein. (127 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (615 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (622 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (558 aa)
ENSCHIP00000024230Serine/threonine-protein phosphatase. (303 aa)
IL17AInterleukin-17A. (153 aa)
MAPK15Mitogen-activated protein kinase. (543 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
UBBUbiquitin B. (323 aa)
ENSCHIP00000027126UBIQUITIN_CONJUGAT_2 domain-containing protein. (132 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (598 aa)
ENSCHIP00000027691Ubiquitin-like domain-containing protein. (116 aa)
CUL1CULLIN_2 domain-containing protein; Belongs to the cullin family. (776 aa)
ENSCHIP00000031302UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (155 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (412 aa)
MAPK8Mitogen-activated protein kinase. (442 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
NOD2Uncharacterized protein. (982 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (344 aa)
ATF7Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (483 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (410 aa)
UBE2V1Ubiquitin conjugating enzyme E2 V1. (147 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (740 aa)
IL25Interleukin 25. (183 aa)
ATF1Activating transcription factor 1. (310 aa)
RPS6KA2Ribosomal protein S6 kinase. (760 aa)
ENSCHIP00000016054Uncharacterized protein; Belongs to the SKP1 family. (157 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (800 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (573 aa)
FBXW11F-box and WD repeat domain containing 11. (563 aa)
PPP4R4Protein phosphatase 4 regulatory subunit 4. (874 aa)
UBCUbiquitin C. (655 aa)
SKP1S-phase kinase associated protein 1. (163 aa)
RPS6KA1Ribosomal protein S6 kinase. (760 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa)
IL17RAInterleukin 17 receptor A. (786 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (349 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (384 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (780 aa)
ENSCHIP00000011946Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
TNIP2TNFAIP3 interacting protein 2. (429 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
FNBP4Formin binding protein 4. (1017 aa)
MAPK10Mitogen-activated protein kinase. (426 aa)
LOC108637886Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform. (309 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (718 aa)
ENSCHIP00000009219Ubiquitin-like domain-containing protein. (108 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
ENSCHIP00000008753Uncharacterized protein. (589 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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