12 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RPA2	Replication protein A2. (270 aa)
	POLD1	DNA polymerase. (1115 aa)
	MEIOB	Meiosis specific with OB-fold. (467 aa)
	POLD4	Uncharacterized protein. (132 aa)
	POLD2	DNA polymerase delta 2, accessory subunit. (469 aa)
	ENSCHIP00000002654	Uncharacterized protein. (121 aa)
	MSH2	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (946 aa)
	LIG1	DNA ligase. (915 aa)
	MSH3	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1119 aa)
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (617 aa)
	POLD3	Uncharacterized protein. (464 aa)
	RPA3	Uncharacterized protein. (121 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCHIP00000002654	LIG1	ENSCHIP00000002654	ENSCHIP00000032333	Uncharacterized protein.	DNA ligase.	0.623
ENSCHIP00000002654	MEIOB	ENSCHIP00000002654	ENSCHIP00000011102	Uncharacterized protein.	Meiosis specific with OB-fold.	0.842
ENSCHIP00000002654	MSH2	ENSCHIP00000002654	ENSCHIP00000025009	Uncharacterized protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.476
ENSCHIP00000002654	POLD1	ENSCHIP00000002654	ENSCHIP00000019836	Uncharacterized protein.	DNA polymerase.	0.626
ENSCHIP00000002654	POLD2	ENSCHIP00000002654	ENSCHIP00000005641	Uncharacterized protein.	DNA polymerase delta 2, accessory subunit.	0.488
ENSCHIP00000002654	POLD3	ENSCHIP00000002654	ENSCHIP00000027965	Uncharacterized protein.	Uncharacterized protein.	0.560
ENSCHIP00000002654	RPA1	ENSCHIP00000002654	ENSCHIP00000032279	Uncharacterized protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.975
ENSCHIP00000002654	RPA2	ENSCHIP00000002654	ENSCHIP00000020251	Uncharacterized protein.	Replication protein A2.	0.865
LIG1	ENSCHIP00000002654	ENSCHIP00000032333	ENSCHIP00000002654	DNA ligase.	Uncharacterized protein.	0.623
LIG1	MEIOB	ENSCHIP00000032333	ENSCHIP00000011102	DNA ligase.	Meiosis specific with OB-fold.	0.614
LIG1	MSH2	ENSCHIP00000032333	ENSCHIP00000025009	DNA ligase.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.463
LIG1	MSH3	ENSCHIP00000032333	ENSCHIP00000032746	DNA ligase.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.471
LIG1	POLD1	ENSCHIP00000032333	ENSCHIP00000019836	DNA ligase.	DNA polymerase.	0.943
LIG1	POLD2	ENSCHIP00000032333	ENSCHIP00000005641	DNA ligase.	DNA polymerase delta 2, accessory subunit.	0.782
LIG1	POLD3	ENSCHIP00000032333	ENSCHIP00000027965	DNA ligase.	Uncharacterized protein.	0.663
LIG1	POLD4	ENSCHIP00000032333	ENSCHIP00000008623	DNA ligase.	Uncharacterized protein.	0.718
LIG1	RPA1	ENSCHIP00000032333	ENSCHIP00000032279	DNA ligase.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.803
LIG1	RPA2	ENSCHIP00000032333	ENSCHIP00000020251	DNA ligase.	Replication protein A2.	0.715
LIG1	RPA3	ENSCHIP00000032333	ENSCHIP00000027638	DNA ligase.	Uncharacterized protein.	0.623
MEIOB	ENSCHIP00000002654	ENSCHIP00000011102	ENSCHIP00000002654	Meiosis specific with OB-fold.	Uncharacterized protein.	0.842