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| | SMYD2 | SET and MYND domain containing 2. (433 aa) |
| | AURKC | Aurora kinase C; Belongs to the protein kinase superfamily. (336 aa) |
| | TAF9B | TATA-box binding protein associated factor 9b. (264 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (417 aa) |
| | PPP1R13B | Protein phosphatase 1 regulatory subunit 13B. (1116 aa) |
| | HIPK4 | Homeodomain interacting protein kinase 4. (616 aa) |
| | EP300 | E1A binding protein p300. (2411 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (430 aa) |
| | AIRE | Autoimmune regulator. (548 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (559 aa) |
| | LY6G5B | Lymphocyte antigen 6 family member G5B. (196 aa) |
| | GATAD2B | GATA zinc finger domain containing 2B. (592 aa) |
| | NOC2L | NOC2 like nucleolar associated transcriptional repressor. (746 aa) |
| | PRMT5 | Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (637 aa) |
| | RFC5 | Replication factor C subunit 5. (339 aa) |
| | ENSCHIP00000016839 | Uncharacterized protein. (240 aa) |
| | CHD3 | Chromodomain helicase DNA binding protein 3. (1979 aa) |
| | PHF20 | PHD finger protein 20. (1010 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3058 aa) |
| | PRR5 | Proline rich 5. (391 aa) |
| | ZNF385A | Zinc finger protein 385A. (393 aa) |
| | ENSCHIP00000015808 | BRCT domain-containing protein. (262 aa) |
| | RBBP4 | WD_REPEATS_REGION domain-containing protein. (426 aa) |
| | BRIP1 | BRCA1 interacting protein C-terminal helicase 1. (1217 aa) |
| | PRKAB2 | Protein kinase AMP-activated non-catalytic subunit beta 2. (271 aa) |
| | RAD9B | Cell cycle checkpoint control protein; Belongs to the rad9 family. (428 aa) |
| | LOC108636199 | Daxx domain-containing protein. (716 aa) |
| | BRD9 | Bromodomain containing 9. (577 aa) |
| | MTA2 | Metastasis associated 1 family member 2. (654 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa) |
| | UBC | Ubiquitin C. (655 aa) |
| | SLF1 | SMC5-SMC6 complex localization factor 1. (1056 aa) |
| | PIP4P2 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa) |
| | RAD1 | Uncharacterized protein. (279 aa) |
| | CHD5 | Chromodomain helicase DNA binding protein 5. (1996 aa) |
| | WRN | WRN RecQ like helicase. (1405 aa) |
| | TAF7L | TAFII55_N domain-containing protein. (300 aa) |
| | LOC102175901 | TAFII28 domain-containing protein. (202 aa) |
| | BRD1 | Bromodomain containing 1. (899 aa) |
| | RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (395 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) |
| | BANP | BTG3 associated nuclear protein. (503 aa) |
| | TOP3A | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1002 aa) |
| | PIP4P1 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (284 aa) |
| | MAPKAPK5 | Protein kinase domain-containing protein. (431 aa) |
| | DAXX | Daxx domain-containing protein. (737 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (421 aa) |
| | ZNF385C | Zinc finger protein 385C. (420 aa) |
| | NUAK2 | NUAK family kinase 2. (644 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (156 aa) |
| | RHNO1 | RAD9-HUS1-RAD1 interacting nuclear orphan 1. (241 aa) |
| | CSNK2B | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (217 aa) |
| | BRPF1 | Bromodomain and PHD finger containing 1. (1213 aa) |
| | MEIOB | Meiosis specific with OB-fold. (467 aa) |
| | KMT5A | Lysine methyltransferase 5A. (422 aa) |
| | EHMT2 | Euchromatic histone lysine methyltransferase 2. (1268 aa) |
| | ING5 | Inhibitor of growth protein. (240 aa) |
| | RBBP8 | RB binding protein 8, endonuclease. (889 aa) |
| | EXO1 | Exonuclease 1. (835 aa) |
| | RMI1 | RecQ mediated genome instability 1. (624 aa) |
| | PIN1 | Peptidyl-prolyl cis-trans isomerase. (163 aa) |
| | RFC3 | Replication factor C subunit 3. (356 aa) |
| | RFFL | Ring finger and FYVE like domain containing E3 ubiquitin protein ligase. (363 aa) |
| | CDK5R2 | Cyclin-dependent kinase 5 activator. (373 aa) |
| | TAF4 | TATA-box binding protein associated factor 4. (1042 aa) |
| | SETD9 | SET domain containing 9. (299 aa) |
| | POU4F2 | POU domain protein. (408 aa) |
| | LOC108637886 | Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform. (309 aa) |
| | TAF10 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa) |
| | ING2 | Inhibitor of growth protein. (283 aa) |
| | ENSCHIP00000009219 | Ubiquitin-like domain-containing protein. (108 aa) |
| | SUPT16H | SPT16 homolog, facilitates chromatin remodeling subunit. (1047 aa) |
| | ENSCHIP00000008753 | Uncharacterized protein. (589 aa) |
| | SSRP1 | FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (709 aa) |
| | ENSCHIP00000008449 | Protein kinase domain-containing protein. (253 aa) |
| | ENSCHIP00000008172 | RING-type domain-containing protein. (96 aa) |
| | TAF13-2 | Uncharacterized protein. (124 aa) |
| | ENSCHIP00000007999 | Uncharacterized protein. (233 aa) |
| | TAF5 | TATA-box binding protein associated factor 5. (752 aa) |
| | NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (754 aa) |
| | RECQL4 | RecQ like helicase 4. (1176 aa) |
| | TP73 | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (640 aa) |
| | ENSCHIP00000007279 | Uncharacterized protein. (111 aa) |
| | JMY | Junction mediating and regulatory protein, p53 cofactor. (982 aa) |
| | EHMT1 | Euchromatic histone lysine methyltransferase 1. (1293 aa) |
| | MDM4 | Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (491 aa) |
| | BLM | BLM RecQ like helicase. (1429 aa) |
| | SGK1 | Non-specific serine/threonine protein kinase. (526 aa) |
| | PIP4K2C | Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (421 aa) |
| | LOC102183623 | Uncharacterized protein. (261 aa) |
| | RNF34 | Ring finger protein 34. (375 aa) |
| | RFC2 | Replication factor C subunit 2. (352 aa) |
| | TP53INP1 | Tumor protein p53 inducible nuclear protein 1. (240 aa) |
| | PML | Promyelocytic leukemia. (868 aa) |
| | ENSCHIP00000004265 | Uncharacterized protein. (393 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | TBP | Uncharacterized protein. (327 aa) |
| | FOXP4 | Forkhead box P4. (777 aa) |
| | ENSCHIP00000003440 | Uncharacterized protein. (94 aa) |
| | HIPK1 | Homeodomain interacting protein kinase 1. (1210 aa) |
| | RAD50 | Zinc-hook domain-containing protein. (1332 aa) |
| | CDK2 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (346 aa) |
| | TAF3 | TATA-box binding protein associated factor 3. (921 aa) |
| | ENSCHIP00000002654 | Uncharacterized protein. (121 aa) |
| | TBPL1 | TATA-box binding protein like 1. (186 aa) |
| | TAF13 | Uncharacterized protein. (130 aa) |
| | CCNG1 | Cyclin G1; Belongs to the cyclin family. (294 aa) |
| | ENSCHIP00000002058 | Uncharacterized protein. (305 aa) |
| | CDK5R1 | Cyclin-dependent kinase 5 activator. (307 aa) |
| | RBBP4-2 | WD_REPEATS_REGION domain-containing protein. (425 aa) |
| | POU4F1 | POU domain protein. (421 aa) |
| | MEAF6 | MYST/Esa1 associated factor 6. (201 aa) |
| | TAF12 | TATA-box binding protein associated factor 12. (161 aa) |
| | PLK3 | Serine/threonine-protein kinase PLK. (647 aa) |
| | KAT6A | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1993 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (350 aa) |
| | ENSCHIP00000000668 | Ubiquitin-like domain-containing protein. (103 aa) |
| | CDK1 | Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (312 aa) |
| | ENSCHIP00000000202 | TAFII28 domain-containing protein. (196 aa) |
| | L3MBTL1 | SAM domain-containing protein. (829 aa) |
| | TAF6 | TATA-box binding protein associated factor 6. (678 aa) |
| | KXD1 | KxDL motif containing 1. (176 aa) |
| | ENSCHIP00000033677 | RanBP2-type domain-containing protein. (336 aa) |
| | TBPL2 | TATA-box binding protein like 2. (357 aa) |
| | MAPKAP1 | MAPK associated protein 1. (522 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1843 aa) |
| | TOPBP1 | DNA topoisomerase II binding protein 1. (1521 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (617 aa) |
| | TP53RK | Protein kinase domain-containing protein. (253 aa) |
| | NUAK1 | NUAK family kinase 1. (662 aa) |
| | CDK5 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa) |
| | ENSCHIP00000031621 | Uncharacterized protein. (159 aa) |
| | PPP1R13L | Protein phosphatase 1 regulatory subunit 13 like. (823 aa) |
| | ENSCHIP00000031435 | Uncharacterized protein. (77 aa) |
| | DYRK4 | Dual specificity tyrosine phosphorylation regulated kinase 4. (649 aa) |
| | TP53INP2 | Tumor protein p53 inducible nuclear protein 2. (224 aa) |
| | CHEK1 | Checkpoint kinase 1; Belongs to the protein kinase superfamily. (476 aa) |
| | TP53BP2 | Tumor protein p53 binding protein 2. (1135 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa) |
| | MBD3 | Methyl-CpG binding domain protein 3. (289 aa) |
| | ZNF385B | Zinc finger protein 385B. (432 aa) |
| | USP7 | Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1103 aa) |
| | AURKA | Aurora kinase A; Belongs to the protein kinase superfamily. (405 aa) |
| | TAF11 | TAFII28 domain-containing protein. (210 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (344 aa) |
| | UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa) |
| | DYRK2 | Dual specificity tyrosine phosphorylation regulated kinase 2. (599 aa) |
| | HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa) |
| | ATRIP | ATR interacting protein. (791 aa) |
| | HUS1 | Checkpoint protein; Belongs to the HUS1 family. (280 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (565 aa) |
| | TAF2 | TATA-box binding protein associated factor 2. (1187 aa) |
| | TPX2 | TPX2 microtubule nucleation factor. (746 aa) |
| | BRD7 | Bromodomain containing 7. (654 aa) |
| | ING1 | Inhibitor of growth protein. (278 aa) |
| | TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (681 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | ENSCHIP00000027862 | WD_REPEATS_REGION domain-containing protein. (404 aa) |
| | CHEK2 | Checkpoint kinase 2. (534 aa) |
| | ENSCHIP00000027691 | Ubiquitin-like domain-containing protein. (116 aa) |
| | PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha. (598 aa) |
| | RPA3 | Uncharacterized protein. (121 aa) |
| | PRDM1 | PR/SET domain 1. (851 aa) |
| | PRKAG3 | Uncharacterized protein. (527 aa) |
| | L3MBTL3 | L3MBTL histone methyl-lysine binding protein 3. (840 aa) |
| | AURKB | Aurora kinase B; Belongs to the protein kinase superfamily. (344 aa) |
| | RICTOR | RPTOR independent companion of MTOR complex 2. (1707 aa) |
| | PIP4K2B | Phosphatidylinositol-5-phosphate 4-kinase type 2 beta. (416 aa) |
| | UBB | Ubiquitin B. (323 aa) |
| | CSNK2A1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa) |
| | PIP4K2A | Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (404 aa) |
| | GATAD2A | GATA zinc finger domain containing 2A. (639 aa) |
| | TTC5 | Tetratricopeptide repeat domain 5. (450 aa) |
| | RBBP7 | RB binding protein 7, chromatin remodeling factor. (469 aa) |
| | TAF4B | TATA-box binding protein associated factor 4b. (871 aa) |
| | HIPK3 | Homeodomain interacting protein kinase 3. (1263 aa) |
| | ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa) |
| | EXD2 | Exonuclease 3'-5' domain containing 2. (642 aa) |
| | PPP2R5C | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (524 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (442 aa) |
| | BARD1 | BRCA1 associated RING domain 1. (775 aa) |
| | MRE11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (724 aa) |
| | RMI2 | Uncharacterized protein. (161 aa) |
| | ENSCHIP00000024230 | Serine/threonine-protein phosphatase. (303 aa) |
| | PRKAB1 | Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa) |
| | HIPK2 | Homeodomain interacting protein kinase 2. (1228 aa) |
| | RFC4 | Replication factor C subunit 4. (364 aa) |
| | CHD4 | Uncharacterized protein. (1905 aa) |
| | CSNK2A2 | Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (350 aa) |
| | RAD17 | RAD17 checkpoint clamp loader component. (709 aa) |
| | BRPF3 | Bromodomain and PHD finger containing 3. (1208 aa) |
| | PRKAG1 | Protein kinase AMP-activated non-catalytic subunit gamma 1. (330 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (464 aa) |
| | TAF1 | Transcription initiation factor TFIID subunit. (1882 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (615 aa) |
| | TDRD3 | Tudor domain containing 3. (762 aa) |
| | ENSCHIP00000021769 | Uncharacterized protein. (384 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (491 aa) |
| | ENSCHIP00000021672 | Uncharacterized protein. (209 aa) |
| | CDK3 | Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa) |
| | DYRK3 | Dual specificity tyrosine phosphorylation regulated kinase 3. (587 aa) |
| | ENSCHIP00000021132 | Ubiquitin-like domain-containing protein. (127 aa) |
| | TXNDC11 | Thioredoxin domain containing 11. (955 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1062 aa) |
| | RPA2 | Replication protein A2. (270 aa) |
| | POU4F3 | POU domain protein. (338 aa) |
