32 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSCHIP00000021132	Ubiquitin-like domain-containing protein. (127 aa)
	POLE3	CBFD_NFYB_HMF domain-containing protein. (147 aa)
	RFC4	Replication factor C subunit 4. (364 aa)
	UBB	Ubiquitin B. (323 aa)
	RPA3	Uncharacterized protein. (121 aa)
	ENSCHIP00000027691	Ubiquitin-like domain-containing protein. (116 aa)
	POLD3	Uncharacterized protein. (464 aa)
	POLE4	DNA polymerase epsilon 4, accessory subunit. (131 aa)
	POLE2	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (518 aa)
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (617 aa)
	KXD1	KxDL motif containing 1. (176 aa)
	RFC5	Replication factor C subunit 5. (339 aa)
	ATAD5	ATPase family AAA domain containing 5. (1894 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	UBC	Ubiquitin C. (655 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	MEIOB	Meiosis specific with OB-fold. (467 aa)
	RCBTB1	RCC1 and BTB domain containing protein 1. (531 aa)
	RFC3	Replication factor C subunit 3. (356 aa)
	RCBTB2	RCC1 and BTB domain containing protein 2. (551 aa)
	ENSCHIP00000009219	Ubiquitin-like domain-containing protein. (108 aa)
	POLD4	Uncharacterized protein. (132 aa)
	POLD2	DNA polymerase delta 2, accessory subunit. (469 aa)
	RFC2	Replication factor C subunit 2. (352 aa)
	POLK	DNA polymerase kappa. (905 aa)
	POLE	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2281 aa)
	ENSCHIP00000002654	Uncharacterized protein. (121 aa)
	ENSCHIP00000000668	Ubiquitin-like domain-containing protein. (103 aa)
	POLD1	DNA polymerase. (1115 aa)
	RPA2	Replication protein A2. (270 aa)
	RFC1	Replication factor C subunit 1. (1143 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATAD5	ENSCHIP00000002654	ENSCHIP00000016824	ENSCHIP00000002654	ATPase family AAA domain containing 5.	Uncharacterized protein.	0.446
ATAD5	ENSCHIP00000021132	ENSCHIP00000016824	ENSCHIP00000021132	ATPase family AAA domain containing 5.	Ubiquitin-like domain-containing protein.	0.421
ATAD5	MEIOB	ENSCHIP00000016824	ENSCHIP00000011102	ATPase family AAA domain containing 5.	Meiosis specific with OB-fold.	0.710
ATAD5	PCNA	ENSCHIP00000016824	ENSCHIP00000015091	ATPase family AAA domain containing 5.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.953
ATAD5	POLD1	ENSCHIP00000016824	ENSCHIP00000019836	ATPase family AAA domain containing 5.	DNA polymerase.	0.748
ATAD5	POLD2	ENSCHIP00000016824	ENSCHIP00000005641	ATPase family AAA domain containing 5.	DNA polymerase delta 2, accessory subunit.	0.630
ATAD5	POLE	ENSCHIP00000016824	ENSCHIP00000003433	ATPase family AAA domain containing 5.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.824
ATAD5	POLE2	ENSCHIP00000016824	ENSCHIP00000028310	ATPase family AAA domain containing 5.	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.779
ATAD5	POLE3	ENSCHIP00000016824	ENSCHIP00000022059	ATPase family AAA domain containing 5.	CBFD_NFYB_HMF domain-containing protein.	0.637
ATAD5	POLE4	ENSCHIP00000016824	ENSCHIP00000028280	ATPase family AAA domain containing 5.	DNA polymerase epsilon 4, accessory subunit.	0.677
ATAD5	POLK	ENSCHIP00000016824	ENSCHIP00000003884	ATPase family AAA domain containing 5.	DNA polymerase kappa.	0.597
ATAD5	RFC1	ENSCHIP00000016824	ENSCHIP00000021706	ATPase family AAA domain containing 5.	Replication factor C subunit 1.	0.728
ATAD5	RFC2	ENSCHIP00000016824	ENSCHIP00000004939	ATPase family AAA domain containing 5.	Replication factor C subunit 2.	0.969
ATAD5	RFC3	ENSCHIP00000016824	ENSCHIP00000010064	ATPase family AAA domain containing 5.	Replication factor C subunit 3.	0.975
ATAD5	RFC4	ENSCHIP00000016824	ENSCHIP00000023106	ATPase family AAA domain containing 5.	Replication factor C subunit 4.	0.988
ATAD5	RFC5	ENSCHIP00000016824	ENSCHIP00000016842	ATPase family AAA domain containing 5.	Replication factor C subunit 5.	0.969
ATAD5	RPA1	ENSCHIP00000016824	ENSCHIP00000032279	ATPase family AAA domain containing 5.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.710
ATAD5	RPA2	ENSCHIP00000016824	ENSCHIP00000020251	ATPase family AAA domain containing 5.	Replication protein A2.	0.485
ATAD5	RPA3	ENSCHIP00000016824	ENSCHIP00000027638	ATPase family AAA domain containing 5.	Uncharacterized protein.	0.446
ATAD5	RPS27A	ENSCHIP00000016824	ENSCHIP00000011667	ATPase family AAA domain containing 5.	Ubiquitin-like domain-containing protein.	0.421