STRINGSTRING
POLD4 POLD4 XAB2 XAB2 ACTR5 ACTR5 SPOCD1 SPOCD1 POLR2B POLR2B INO80D INO80D SUMO4 SUMO4 PPP1R42 PPP1R42 XPA XPA INO80 INO80 PIAS3 PIAS3 ERCC6 ERCC6 COPS7B COPS7B POLD2 POLD2 RFC2 RFC2 POLR2J POLR2J SUMO1 SUMO1 ENSCHIP00000004279 ENSCHIP00000004279 LOC102174442 LOC102174442 ENSCHIP00000003970 ENSCHIP00000003970 ENSCHIP00000003603 ENSCHIP00000003603 VWA5B2 VWA5B2 POLE POLE LOC102188771 LOC102188771 POLR2H POLR2H ENSCHIP00000002654 ENSCHIP00000002654 NRDE2 NRDE2 LOC102175358 LOC102175358 ENSCHIP00000001859 ENSCHIP00000001859 ENSCHIP00000001457 ENSCHIP00000001457 ENSCHIP00000001244 ENSCHIP00000001244 GTF2H5 GTF2H5 ENSCHIP00000000668 ENSCHIP00000000668 CUL4A CUL4A INO80C INO80C POLK POLK RBX1 RBX1 ENSCHIP00000031302 ENSCHIP00000031302 POLR2D POLR2D RPA1 RPA1 MNAT1 MNAT1 CUL4B CUL4B DDB2 DDB2 WBP1 WBP1 COPS2 COPS2 ENSCHIP00000025548 ENSCHIP00000025548 GTF2H4 GTF2H4 ERCC4 ERCC4 TCEA1 TCEA1 RAD23B RAD23B UBB UBB POLR2L POLR2L ERCC2 ERCC2 ENSCHIP00000027126 ENSCHIP00000027126 RPA3 RPA3 ENSCHIP00000027691 ENSCHIP00000027691 ENSCHIP00000027945 ENSCHIP00000027945 POLD3 POLD3 USP40 USP40 ENSCHIP00000028014 ENSCHIP00000028014 RNF111 RNF111 POLR2G POLR2G CCNH CCNH VWA5B1 VWA5B1 POLE4 POLE4 CDK7 CDK7 POLE2 POLE2 LIG3 LIG3 ENSCHIP00000028361 ENSCHIP00000028361 INO80B INO80B UBA52 UBA52 USP7 USP7 PARP2 PARP2 TFPT TFPT ENSCHIP00000030655 ENSCHIP00000030655 AQR AQR ENSCHIP00000030962 ENSCHIP00000030962 ENSCHIP00000031099 ENSCHIP00000031099 ERCC1 ERCC1 POLR2A POLR2A KXD1 KXD1 COPS8 COPS8 GPS1 GPS1 ACTG1 ACTG1 TCEANC2 TCEANC2 SUMO2 SUMO2 LIG1 LIG1 ENSCHIP00000023574 ENSCHIP00000023574 BIVM BIVM NFRKB NFRKB RFC4 RFC4 XRCC1 XRCC1 ENSCHIP00000022726 ENSCHIP00000022726 COPS5 COPS5 POLE3 POLE3 RFC1 RFC1 VWA5A VWA5A VTCN1 VTCN1 UVSSA UVSSA ENSCHIP00000021132 ENSCHIP00000021132 RUVBL1 RUVBL1 MCRS1 MCRS1 CETN2 CETN2 RPA2 RPA2 ENSCHIP00000020238 ENSCHIP00000020238 POLD1 POLD1 PRPF19 PRPF19 PARP1 PARP1 NFATC2IP NFATC2IP ENSCHIP00000018712 ENSCHIP00000018712 ENSCHIP00000018629 ENSCHIP00000018629 EP300 EP300 XPC XPC UBE2I UBE2I RAD23A RAD23A INO80E INO80E RFC5 RFC5 ATAD5 ATAD5 TCEA3 TCEA3 TCEA2 TCEA2 ERCC8 ERCC8 TCEANC TCEANC ENSCHIP00000015544 ENSCHIP00000015544 ENSCHIP00000015411 ENSCHIP00000015411 PARP3 PARP3 CETN3 CETN3 SUMO3 SUMO3 PCNA PCNA ENSCHIP00000014639 ENSCHIP00000014639 UBC UBC ACTR8 ACTR8 DDB1 DDB1 COPS4 COPS4 GTF2H1 GTF2H1 PHF3 PHF3 ERCC3 ERCC3 ERCC5 ERCC5 POLR2E POLR2E UPK3BL2 UPK3BL2 PIAS1 PIAS1 USP45 USP45 CHD1L CHD1L RPS27A RPS27A UBE2V2 UBE2V2 COPS6 COPS6 YY1 YY1 MEIOB MEIOB RCBTB1 RCBTB1 COPS7A COPS7A POLR2F POLR2F POLR2K POLR2K ZNF830 ZNF830 RFC3 RFC3 RCBTB2 RCBTB2 PPIE PPIE ENSCHIP00000009605 ENSCHIP00000009605 LOC102185505 LOC102185505 GTF2H3 GTF2H3 WDR76 WDR76 ENSCHIP00000009219 ENSCHIP00000009219 ENSCHIP00000009163 ENSCHIP00000009163 POLR2C POLR2C ENSCHIP00000009097 ENSCHIP00000009097 POLR2I POLR2I RPAP3 RPAP3 ENSCHIP00000008863 ENSCHIP00000008863 COPS3 COPS3 KCTD2 KCTD2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
POLD4Uncharacterized protein. (132 aa)
XAB2XPA binding protein 2. (892 aa)
ACTR5Actin related protein 5; Belongs to the actin family. (615 aa)
SPOCD1SPOC domain containing 1. (1079 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
INO80DINO80 complex subunit D. (1026 aa)
SUMO4Small ubiquitin-related modifier. (95 aa)
PPP1R42Protein phosphatase 1 regulatory subunit 42. (370 aa)
XPAXPA, DNA damage recognition and repair factor. (273 aa)
INO80INO80 complex ATPase subunit. (1566 aa)
PIAS3Protein inhibitor of activated STAT 3. (628 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1481 aa)
COPS7BCOP9 signalosome subunit 7B. (264 aa)
POLD2DNA polymerase delta 2, accessory subunit. (469 aa)
RFC2Replication factor C subunit 2. (352 aa)
POLR2JRNA_pol_L_2 domain-containing protein. (136 aa)
SUMO1Small ubiquitin-related modifier. (101 aa)
ENSCHIP00000004279Uncharacterized protein. (101 aa)
LOC102174442Uncharacterized protein. (284 aa)
ENSCHIP00000003970Uncharacterized protein. (94 aa)
ENSCHIP00000003603Uncharacterized protein. (57 aa)
VWA5B2Von Willebrand factor A domain containing 5B2. (1254 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2281 aa)
LOC102188771Zf-rbx1 domain-containing protein. (108 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
ENSCHIP00000002654Uncharacterized protein. (121 aa)
NRDE2NRDE-2, necessary for RNA interference, domain containing. (1153 aa)
LOC102175358Uncharacterized protein. (101 aa)
ENSCHIP00000001859Uncharacterized protein. (101 aa)
ENSCHIP00000001457PAPA-1 domain-containing protein. (349 aa)
ENSCHIP00000001244Uncharacterized protein. (134 aa)
GTF2H5General transcription factor IIH subunit 5. (85 aa)
ENSCHIP00000000668Ubiquitin-like domain-containing protein. (103 aa)
CUL4ACullin 4A; Belongs to the cullin family. (764 aa)
INO80CINO80 complex subunit C. (192 aa)
POLKDNA polymerase kappa. (905 aa)
RBX1RING-type domain-containing protein. (108 aa)
ENSCHIP00000031302UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (155 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (617 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
CUL4BCullin 4B; Belongs to the cullin family. (1027 aa)
DDB2Damage specific DNA binding protein 2. (411 aa)
WBP1WW domain binding protein 1. (303 aa)
COPS2COP9 signalosome subunit 2. (443 aa)
ENSCHIP00000025548Uncharacterized protein. (51 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (463 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (916 aa)
TCEA1Uncharacterized protein. (361 aa)
RAD23BRAD23 homolog B, nucleotide excision repair protein. (408 aa)
UBBUbiquitin B. (323 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
ENSCHIP00000027126UBIQUITIN_CONJUGAT_2 domain-containing protein. (132 aa)
RPA3Uncharacterized protein. (121 aa)
ENSCHIP00000027691Ubiquitin-like domain-containing protein. (116 aa)
ENSCHIP00000027945Uncharacterized protein. (92 aa)
POLD3Uncharacterized protein. (464 aa)
USP40Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family. (1234 aa)
ENSCHIP00000028014Uncharacterized protein. (103 aa)
RNF111Ring finger protein 111. (986 aa)
POLR2GRNA polymerase II subunit G. (189 aa)
CCNHCyclin H; Belongs to the cyclin family. (329 aa)
VWA5B1Von Willebrand factor A domain containing 5B1. (1183 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (131 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (347 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (518 aa)
LIG3DNA ligase. (1004 aa)
ENSCHIP00000028361Uncharacterized protein. (251 aa)
INO80BPAPA-1 domain-containing protein. (373 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1103 aa)
PARP2Poly [ADP-ribose] polymerase. (533 aa)
TFPTTCF3 fusion partner. (254 aa)
ENSCHIP00000030655Uncharacterized protein. (63 aa)
AQRRNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1471 aa)
ENSCHIP00000030962Uncharacterized protein. (275 aa)
ENSCHIP00000031099Uncharacterized protein. (113 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (294 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1970 aa)
KXD1KxDL motif containing 1. (176 aa)
COPS8COP9 signalosome subunit 8. (209 aa)
GPS1G protein pathway suppressor 1. (471 aa)
ACTG1Actin gamma 1. (376 aa)
TCEANC2Transcription elongation factor A N-terminal and central domain containing 2. (223 aa)
SUMO2Small ubiquitin-related modifier. (95 aa)
LIG1DNA ligase. (915 aa)
ENSCHIP00000023574Uncharacterized protein. (61 aa)
BIVMUncharacterized protein. (502 aa)
NFRKBNuclear factor related to kappaB binding protein. (1298 aa)
RFC4Replication factor C subunit 4. (364 aa)
XRCC1X-ray repair cross complementing 1. (632 aa)
ENSCHIP00000022726Uncharacterized protein. (88 aa)
COPS5COP9 signalosome subunit 5. (334 aa)
POLE3CBFD_NFYB_HMF domain-containing protein. (147 aa)
RFC1Replication factor C subunit 1. (1143 aa)
VWA5AVon Willebrand factor A domain containing 5A. (783 aa)
VTCN1V-set domain containing T cell activation inhibitor 1. (270 aa)
UVSSAUV stimulated scaffold protein A. (663 aa)
ENSCHIP00000021132Ubiquitin-like domain-containing protein. (127 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
MCRS1Microspherule protein 1. (462 aa)
CETN2Centrin 2. (166 aa)
RPA2Replication protein A2. (270 aa)
ENSCHIP00000020238Rad60-SLD domain-containing protein. (127 aa)
POLD1DNA polymerase. (1115 aa)
PRPF19Pre-mRNA processing factor 19. (504 aa)
PARP1Poly [ADP-ribose] polymerase. (1020 aa)
NFATC2IPNuclear factor of activated T cells 2 interacting protein. (417 aa)
ENSCHIP00000018712Uncharacterized protein. (47 aa)
ENSCHIP00000018629Rad60-SLD domain-containing protein. (90 aa)
EP300E1A binding protein p300. (2411 aa)
XPCXPC complex subunit, DNA damage recognition and repair factor. (877 aa)
UBE2IUbiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
RAD23ARAD23 homolog A, nucleotide excision repair protein. (368 aa)
INO80EINO80 complex subunit E. (241 aa)
RFC5Replication factor C subunit 5. (339 aa)
ATAD5ATPase family AAA domain containing 5. (1894 aa)
TCEA3Transcription elongation factor A3. (514 aa)
TCEA2Transcription elongation factor A2. (299 aa)
ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (397 aa)
TCEANCTranscription elongation factor A N-terminal and central domain containing. (394 aa)
ENSCHIP00000015544Uncharacterized protein. (73 aa)
ENSCHIP00000015411Uncharacterized protein. (97 aa)
PARP3Poly [ADP-ribose] polymerase. (525 aa)
CETN3Centrin 3. (177 aa)
SUMO3Small ubiquitin-related modifier. (104 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
ENSCHIP00000014639Uncharacterized protein. (93 aa)
UBCUbiquitin C. (655 aa)
ACTR8Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (624 aa)
DDB1Damage specific DNA binding protein 1. (1140 aa)
COPS4COP9 signalosome subunit 4. (406 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
PHF3PHD finger protein 3. (2028 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
ERCC5ERCC excision repair 5, endonuclease. (1190 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
UPK3BL2Uncharacterized protein. (253 aa)
PIAS1Protein inhibitor of activated STAT 1. (651 aa)
USP45Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (815 aa)
CHD1LChromodomain helicase DNA binding protein 1 like. (893 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
UBE2V2Ubiquitin conjugating enzyme E2 V2. (148 aa)
COPS6COP9 signalosome subunit 6. (328 aa)
YY1YY1 transcription factor. (415 aa)
MEIOBMeiosis specific with OB-fold. (467 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
COPS7ACOP9 signalosome subunit 7A. (277 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
POLR2KUncharacterized protein. (58 aa)
ZNF830Zinc finger protein 830. (361 aa)
RFC3Replication factor C subunit 3. (356 aa)
RCBTB2RCC1 and BTB domain containing protein 2. (551 aa)
PPIEPeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (292 aa)
ENSCHIP00000009605Uncharacterized protein. (61 aa)
LOC102185505General transcription factor IIH subunit. (388 aa)
GTF2H3General transcription factor IIH subunit 3. (307 aa)
WDR76WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (626 aa)
ENSCHIP00000009219Ubiquitin-like domain-containing protein. (108 aa)
ENSCHIP00000009163Uncharacterized protein. (122 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
ENSCHIP00000009097Uncharacterized protein. (88 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
RPAP3RNA polymerase II associated protein 3. (665 aa)
ENSCHIP00000008863Uncharacterized protein. (103 aa)
COPS3COP9 signalosome subunit 3. (423 aa)
KCTD2Potassium channel tetramerization domain containing 2. (264 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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