52 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	POLK	DNA polymerase kappa. (905 aa)
	POLE	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2281 aa)
	LOC102188771	Zf-rbx1 domain-containing protein. (108 aa)
	ENSCHIP00000002654	Uncharacterized protein. (121 aa)
	GTF2H5	General transcription factor IIH subunit 5. (85 aa)
	ENSCHIP00000000668	Ubiquitin-like domain-containing protein. (103 aa)
	CUL4A	Cullin 4A; Belongs to the cullin family. (764 aa)
	POLE3	CBFD_NFYB_HMF domain-containing protein. (147 aa)
	RFC1	Replication factor C subunit 1. (1143 aa)
	ENSCHIP00000021132	Ubiquitin-like domain-containing protein. (127 aa)
	RPA2	Replication protein A2. (270 aa)
	POLD1	DNA polymerase. (1115 aa)
	PARP1	Poly [ADP-ribose] polymerase. (1020 aa)
	RFC5	Replication factor C subunit 5. (339 aa)
	PARP3	Poly [ADP-ribose] polymerase. (525 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	UBC	Ubiquitin C. (655 aa)
	DDB1	Damage specific DNA binding protein 1. (1140 aa)
	GTF2H1	General transcription factor IIH subunit 1. (548 aa)
	ERCC3	ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
	KXD1	KxDL motif containing 1. (176 aa)
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (617 aa)
	RBX1	RING-type domain-containing protein. (108 aa)
	ERCC1	ERCC excision repair 1, endonuclease non-catalytic subunit. (294 aa)
	PARP2	Poly [ADP-ribose] polymerase. (533 aa)
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	POLE2	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (518 aa)
	POLE4	DNA polymerase epsilon 4, accessory subunit. (131 aa)
	POLD3	Uncharacterized protein. (464 aa)
	ENSCHIP00000027691	Ubiquitin-like domain-containing protein. (116 aa)
	RPA3	Uncharacterized protein. (121 aa)
	ERCC2	ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
	UBB	Ubiquitin B. (323 aa)
	ERCC4	ERCC excision repair 4, endonuclease catalytic subunit. (916 aa)
	GTF2H4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (463 aa)
	CUL4B	Cullin 4B; Belongs to the cullin family. (1027 aa)
	DDB2	Damage specific DNA binding protein 2. (411 aa)
	BIVM	Uncharacterized protein. (502 aa)
	RFC4	Replication factor C subunit 4. (364 aa)
	ERCC5	ERCC excision repair 5, endonuclease. (1190 aa)
	CHD1L	Chromodomain helicase DNA binding protein 1 like. (893 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	RCBTB1	RCC1 and BTB domain containing protein 1. (531 aa)
	RFC3	Replication factor C subunit 3. (356 aa)
	RCBTB2	RCC1 and BTB domain containing protein 2. (551 aa)
	LOC102185505	General transcription factor IIH subunit. (388 aa)
	GTF2H3	General transcription factor IIH subunit 3. (307 aa)
	ENSCHIP00000009219	Ubiquitin-like domain-containing protein. (108 aa)
	POLD4	Uncharacterized protein. (132 aa)
	XPA	XPA, DNA damage recognition and repair factor. (273 aa)
	POLD2	DNA polymerase delta 2, accessory subunit. (469 aa)
	RFC2	Replication factor C subunit 2. (352 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BIVM	CHD1L	ENSCHIP00000023511	ENSCHIP00000011908	Uncharacterized protein.	Chromodomain helicase DNA binding protein 1 like.	0.818
BIVM	CUL4A	ENSCHIP00000023511	ENSCHIP00000000333	Uncharacterized protein.	Cullin 4A; Belongs to the cullin family.	0.531
BIVM	CUL4B	ENSCHIP00000023511	ENSCHIP00000024785	Uncharacterized protein.	Cullin 4B; Belongs to the cullin family.	0.534
BIVM	DDB1	ENSCHIP00000023511	ENSCHIP00000013716	Uncharacterized protein.	Damage specific DNA binding protein 1.	0.651
BIVM	DDB2	ENSCHIP00000023511	ENSCHIP00000024487	Uncharacterized protein.	Damage specific DNA binding protein 2.	0.541
BIVM	ENSCHIP00000002654	ENSCHIP00000023511	ENSCHIP00000002654	Uncharacterized protein.	Uncharacterized protein.	0.467
BIVM	ENSCHIP00000021132	ENSCHIP00000023511	ENSCHIP00000021132	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.431
BIVM	ERCC1	ENSCHIP00000023511	ENSCHIP00000031141	Uncharacterized protein.	ERCC excision repair 1, endonuclease non-catalytic subunit.	0.725
BIVM	ERCC2	ENSCHIP00000023511	ENSCHIP00000026861	Uncharacterized protein.	ERCC excision repair 2, TFIIH core complex helicase subunit.	0.891
BIVM	ERCC3	ENSCHIP00000023511	ENSCHIP00000013017	Uncharacterized protein.	ERCC excision repair 3, TFIIH core complex helicase subunit.	0.905
BIVM	ERCC4	ENSCHIP00000023511	ENSCHIP00000026065	Uncharacterized protein.	ERCC excision repair 4, endonuclease catalytic subunit.	0.809
BIVM	ERCC5	ENSCHIP00000023511	ENSCHIP00000012626	Uncharacterized protein.	ERCC excision repair 5, endonuclease.	0.814
BIVM	GTF2H1	ENSCHIP00000023511	ENSCHIP00000013203	Uncharacterized protein.	General transcription factor IIH subunit 1.	0.928
BIVM	GTF2H3	ENSCHIP00000023511	ENSCHIP00000009508	Uncharacterized protein.	General transcription factor IIH subunit 3.	0.630
BIVM	GTF2H4	ENSCHIP00000023511	ENSCHIP00000025980	Uncharacterized protein.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.551
BIVM	GTF2H5	ENSCHIP00000023511	ENSCHIP00000000855	Uncharacterized protein.	General transcription factor IIH subunit 5.	0.642
BIVM	LOC102185505	ENSCHIP00000023511	ENSCHIP00000009578	Uncharacterized protein.	General transcription factor IIH subunit.	0.827
BIVM	LOC102188771	ENSCHIP00000023511	ENSCHIP00000003016	Uncharacterized protein.	Zf-rbx1 domain-containing protein.	0.465
BIVM	PARP1	ENSCHIP00000023511	ENSCHIP00000019007	Uncharacterized protein.	Poly [ADP-ribose] polymerase.	0.502
BIVM	PARP2	ENSCHIP00000023511	ENSCHIP00000029449	Uncharacterized protein.	Poly [ADP-ribose] polymerase.	0.486