(9 nodes) TP53 Regulates Transcription of Caspase Activators and Caspases network (Capra hircus)

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Your Input:
	LRCH2	Leucine rich repeats and calponin homology domain containing 2. (735 aa)
	PIDD1	P53-induced death domain protein 1. (913 aa)
	LRCH1	Leucine rich repeats and calponin homology domain containing 1. (726 aa)
	NLRC4	NLR family CARD domain containing 4. (1024 aa)
	LRCH3	Leucine rich repeats and calponin homology domain containing 3. (799 aa)
	CRADD	CASP2 and RIPK1 domain containing adaptor with death domain. (199 aa)
	CASP2	Caspase 2; Belongs to the peptidase C14A family. (456 aa)
	ATM	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3058 aa)
	LRCH4	Leucine rich repeats and calponin homology domain containing 4. (667 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATM	PIDD1	ENSCHIP00000016363	ENSCHIP00000023138	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	P53-induced death domain protein 1.	0.891
CASP2	CRADD	ENSCHIP00000018562	ENSCHIP00000027459	Caspase 2; Belongs to the peptidase C14A family.	CASP2 and RIPK1 domain containing adaptor with death domain.	0.966
CASP2	PIDD1	ENSCHIP00000018562	ENSCHIP00000023138	Caspase 2; Belongs to the peptidase C14A family.	P53-induced death domain protein 1.	0.940
CRADD	CASP2	ENSCHIP00000027459	ENSCHIP00000018562	CASP2 and RIPK1 domain containing adaptor with death domain.	Caspase 2; Belongs to the peptidase C14A family.	0.966
CRADD	PIDD1	ENSCHIP00000027459	ENSCHIP00000023138	CASP2 and RIPK1 domain containing adaptor with death domain.	P53-induced death domain protein 1.	0.996
LRCH1	LRCH3	ENSCHIP00000009930	ENSCHIP00000030994	Leucine rich repeats and calponin homology domain containing 1.	Leucine rich repeats and calponin homology domain containing 3.	0.558
LRCH1	LRCH4	ENSCHIP00000009930	ENSCHIP00000020390	Leucine rich repeats and calponin homology domain containing 1.	Leucine rich repeats and calponin homology domain containing 4.	0.584
LRCH3	LRCH1	ENSCHIP00000030994	ENSCHIP00000009930	Leucine rich repeats and calponin homology domain containing 3.	Leucine rich repeats and calponin homology domain containing 1.	0.558
LRCH3	LRCH4	ENSCHIP00000030994	ENSCHIP00000020390	Leucine rich repeats and calponin homology domain containing 3.	Leucine rich repeats and calponin homology domain containing 4.	0.550
LRCH4	LRCH1	ENSCHIP00000020390	ENSCHIP00000009930	Leucine rich repeats and calponin homology domain containing 4.	Leucine rich repeats and calponin homology domain containing 1.	0.584
LRCH4	LRCH3	ENSCHIP00000020390	ENSCHIP00000030994	Leucine rich repeats and calponin homology domain containing 4.	Leucine rich repeats and calponin homology domain containing 3.	0.550
PIDD1	ATM	ENSCHIP00000023138	ENSCHIP00000016363	P53-induced death domain protein 1.	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	0.891
PIDD1	CASP2	ENSCHIP00000023138	ENSCHIP00000018562	P53-induced death domain protein 1.	Caspase 2; Belongs to the peptidase C14A family.	0.940
PIDD1	CRADD	ENSCHIP00000023138	ENSCHIP00000027459	P53-induced death domain protein 1.	CASP2 and RIPK1 domain containing adaptor with death domain.	0.996