(51 nodes) Glycolysis network (Capra hircus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PFKL	Phosphofructokinase, liver type. (803 aa)
	ENSCHIP00000016404	Uncharacterized protein. (143 aa)
	ENSCHIP00000016635	Uncharacterized protein. (142 aa)
	ENSCHIP00000019185	Gp_dh_N domain-containing protein. (273 aa)
	ENO2	Uncharacterized protein. (441 aa)
	MYCBPAP	MYCBP associated protein. (947 aa)
	ENSCHIP00000020431	Uncharacterized protein. (246 aa)
	ENO4	Enolase 4. (613 aa)
	ENO3	Enolase 3. (444 aa)
	LOC102190753	Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (305 aa)
	ADPGK	ADP dependent glucokinase. (497 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	LOC102181259	Uncharacterized protein. (1216 aa)
	GNPDA2	Glucosamine-6-phosphate isomerase. (297 aa)
	PGAM1	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
	ENSCHIP00000026945	Enolase_C domain-containing protein. (279 aa)
	PFKFB1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. (471 aa)
	PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3. (603 aa)
	PFKFB2	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2. (531 aa)
	HK3	Hexokinase 3. (924 aa)
	PFKP	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (791 aa)
	PFKM	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (838 aa)
	PGM2L1	Phosphoglucomutase 2 like 1. (629 aa)
	ENSCHIP00000032066	Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (308 aa)
	PKM	Pyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
	TPI1	Triosephosphate isomerase. (295 aa)
	ENO1	Enolase 1. (434 aa)
	PFKFB4	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4. (469 aa)
	GCK	Phosphotransferase. (465 aa)
	GNPDA1	Glucosamine-6-phosphate isomerase. (289 aa)
	BPGM	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (259 aa)
	SHLD1	Shieldin complex subunit 1. (206 aa)
	PDXP	Pyridoxal phosphatase; Belongs to the HAD-like hydrolase superfamily. (313 aa)
	PGP	Phosphoglycolate phosphatase; Belongs to the HAD-like hydrolase superfamily. (323 aa)
	ALDOA	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (416 aa)
	LOC102181016	Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (318 aa)
	HK2	Hexokinase 2. (917 aa)
	ENSCHIP00000009167	Gp_dh_C domain-containing protein. (135 aa)
	HKDC1	Hexokinase domain containing 1. (918 aa)
	PGK1	Phosphoglycerate kinase. (424 aa)
	GAPDHS	Glyceraldehyde-3-phosphate dehydrogenase. (385 aa)
	ALDOC	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (493 aa)
	LOC102176799	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	NUP205	Nucleoporin 205. (2003 aa)
	PGAM2	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (253 aa)
	PGK2	Phosphoglycerate kinase. (417 aa)
	ALDOB	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
	HK1	Hexokinase 1. (945 aa)
	GPI	Glucose-6-phosphate isomerase; Belongs to the GPI family. (557 aa)
	LOC102176111	Triosephosphate isomerase. (201 aa)
	FAM126B	Family with sequence similarity 126 member B. (530 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADPGK	ALDOA	ENSCHIP00000025938	ENSCHIP00000011329	ADP dependent glucokinase.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.908
ADPGK	ALDOB	ENSCHIP00000025938	ENSCHIP00000001562	ADP dependent glucokinase.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.908
ADPGK	ALDOC	ENSCHIP00000025938	ENSCHIP00000004951	ADP dependent glucokinase.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.908
ADPGK	ENO1	ENSCHIP00000025938	ENSCHIP00000015366	ADP dependent glucokinase.	Enolase 1.	0.479
ADPGK	GCK	ENSCHIP00000025938	ENSCHIP00000014563	ADP dependent glucokinase.	Phosphotransferase.	0.939
ADPGK	GPI	ENSCHIP00000025938	ENSCHIP00000015777	ADP dependent glucokinase.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.987
ADPGK	HK1	ENSCHIP00000025938	ENSCHIP00000000719	ADP dependent glucokinase.	Hexokinase 1.	0.946
ADPGK	HK2	ENSCHIP00000025938	ENSCHIP00000009707	ADP dependent glucokinase.	Hexokinase 2.	0.936
ADPGK	HK3	ENSCHIP00000025938	ENSCHIP00000029968	ADP dependent glucokinase.	Hexokinase 3.	0.940
ADPGK	HKDC1	ENSCHIP00000025938	ENSCHIP00000007027	ADP dependent glucokinase.	Hexokinase domain containing 1.	0.940
ADPGK	PGK1	ENSCHIP00000025938	ENSCHIP00000005700	ADP dependent glucokinase.	Phosphoglycerate kinase.	0.539
ADPGK	PGK2	ENSCHIP00000025938	ENSCHIP00000001811	ADP dependent glucokinase.	Phosphoglycerate kinase.	0.433
ADPGK	PGM2L1	ENSCHIP00000025938	ENSCHIP00000031571	ADP dependent glucokinase.	Phosphoglucomutase 2 like 1.	0.512
ADPGK	TPI1	ENSCHIP00000025938	ENSCHIP00000015387	ADP dependent glucokinase.	Triosephosphate isomerase.	0.470
ALDOA	ADPGK	ENSCHIP00000011329	ENSCHIP00000025938	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	ADP dependent glucokinase.	0.908
ALDOA	ALDOB	ENSCHIP00000011329	ENSCHIP00000001562	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.979
ALDOA	ALDOC	ENSCHIP00000011329	ENSCHIP00000004951	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.975
ALDOA	BPGM	ENSCHIP00000011329	ENSCHIP00000013663	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.	0.948
ALDOA	ENO1	ENSCHIP00000011329	ENSCHIP00000015366	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Enolase 1.	0.985
ALDOA	ENO2	ENSCHIP00000011329	ENSCHIP00000019330	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Uncharacterized protein.	0.955