Your Input: | |
| | PPP6C | Serine/threonine-protein phosphatase. (305 aa) |
| | LOC102184017 | Histone H2B type 1. (126 aa) |
| | RCBTB1 | RCC1 and BTB domain containing protein 1. (531 aa) |
| | CENPL | Centromere protein L. (346 aa) |
| | CENPN | Centromere protein N. (343 aa) |
| | MEIOB | Meiosis specific with OB-fold. (467 aa) |
| | ATRX | ATRX chromatin remodeler. (2105 aa) |
| | LOC102172676 | Histone H2B type 2-E-like. (126 aa) |
| | SMARCA5 | Uncharacterized protein. (1052 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (421 aa) |
| | DAXX | Daxx domain-containing protein. (737 aa) |
| | NPM1 | Uncharacterized protein. (276 aa) |
| | CENPH | Centromere protein H. (244 aa) |
| | RTEL1 | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1212 aa) |
| | CENPO | Uncharacterized protein. (296 aa) |
| | ENSCHIP00000012521 | Uncharacterized protein. (177 aa) |
| | ENSCHIP00000012571 | Uncharacterized protein. (386 aa) |
| | DSCC1 | Uncharacterized protein. (388 aa) |
| | PIF1 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (649 aa) |
| | POT1 | Protection of telomeres 1. (785 aa) |
| | WRN | WRN RecQ like helicase. (1405 aa) |
| | NHP2 | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (153 aa) |
| | ITGB3BP | Uncharacterized protein. (197 aa) |
| | LOC108634345 | Uncharacterized protein. (206 aa) |
| | PPP6R2 | Protein phosphatase 6 regulatory subunit 2. (917 aa) |
| | WRAP53 | WD repeat containing antisense to TP53. (540 aa) |
| | LOC108636199 | Daxx domain-containing protein. (716 aa) |
| | CENPC | Centromere protein C. (953 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | GAR1 | H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (214 aa) |
| | RBBP4 | WD_REPEATS_REGION domain-containing protein. (426 aa) |
| | ENSCHIP00000015897 | Histone domain-containing protein. (141 aa) |
| | LOC108637664 | Uncharacterized protein. (1041 aa) |
| | CENPS | Centromere protein S. (131 aa) |
| | ENSCHIP00000016741 | Histone H2A; Belongs to the histone H2A family. (140 aa) |
| | POLA1 | DNA polymerase. (1468 aa) |
| | RFC5 | Replication factor C subunit 5. (339 aa) |
| | DKC1 | Dyskerin pseudouridine synthase 1. (506 aa) |
| | CENPK | Centromere protein K. (271 aa) |
| | ANKRD44 | Ankyrin repeat domain 44. (993 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (430 aa) |
| | LOC102183306 | Histone H2A; Belongs to the histone H2A family. (128 aa) |
| | ENSCHIP00000019684 | Uncharacterized protein. (287 aa) |
| | POLD1 | DNA polymerase. (1115 aa) |
| | RPA2 | Replication protein A2. (270 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1062 aa) |
| | RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) |
| | STN1 | CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (370 aa) |
| | CDK3 | Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa) |
| | RFC1 | Replication factor C subunit 1. (1143 aa) |
| | PPP6R3 | Protein phosphatase 6 regulatory subunit 3. (879 aa) |
| | HJURP | Holliday junction recognition protein. (694 aa) |
| | RFC4 | Replication factor C subunit 4. (364 aa) |
| | TRUB1 | TruB pseudouridine synthase family member 1. (351 aa) |
| | TERF2IP | Uncharacterized protein. (400 aa) |
| | POLA2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (603 aa) |
| | ENSCHIP00000024414 | Uncharacterized protein. (57 aa) |
| | CENPQ | Centromere protein Q. (269 aa) |
| | LOC102189503 | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | EXD2 | Exonuclease 3'-5' domain containing 2. (642 aa) |
| | ANKRD28 | Ankyrin repeat domain 28. (1083 aa) |
| | ENSCHIP00000025553 | annotation not available (143 aa) |
| | RBBP7 | RB binding protein 7, chromatin remodeling factor. (469 aa) |
| | ENSCHIP00000026297 | Histone domain-containing protein; Belongs to the histone H2B family. (112 aa) |
| | ANKRD66 | Ankyrin repeat domain 66. (210 aa) |
| | LOC102190909 | Histone H3.3. (136 aa) |
| | H2AZ2 | Histone H2A; Belongs to the histone H2A family. (127 aa) |
| | RPA3 | Uncharacterized protein. (121 aa) |
| | TINF2 | TERF1 interacting nuclear factor 2. (458 aa) |
| | ENSCHIP00000027862 | WD_REPEATS_REGION domain-containing protein. (404 aa) |
| | POLD3 | Uncharacterized protein. (464 aa) |
| | MIS18BP1 | MIS18 binding protein 1. (1066 aa) |
| | KNL1 | Kinetochore scaffold 1. (2160 aa) |
| | ENSCHIP00000029134 | Uncharacterized protein. (95 aa) |
| | RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (471 aa) |
| | TERF2 | Telomeric repeat binding factor 2. (543 aa) |
| | CTC1 | CST telomere replication complex component 1. (1210 aa) |
| | RSF1 | Remodeling and spacing factor 1. (1429 aa) |
| | ACD | ACD shelterin complex subunit and telomerase recruitment factor. (458 aa) |
| | PRIM2 | Uncharacterized protein. (219 aa) |
| | OIP5 | Opa interacting protein 5. (229 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (617 aa) |
| | LIG1 | DNA ligase. (915 aa) |
| | CENPT | Centromere protein T. (563 aa) |
| | PRIM1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (401 aa) |
| | ENSCHIP00000011074 | annotation not available (103 aa) |
| | H2BC21 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | H2BE1 | Histone H2B; Belongs to the histone H2B family. (122 aa) |
| | ENSCHIP00000010286 | Uncharacterized protein. (242 aa) |
| | RFC3 | Replication factor C subunit 3. (356 aa) |
| | RCBTB2 | RCC1 and BTB domain containing protein 2. (551 aa) |
| | CENPU | Centromere protein U. (433 aa) |
| | SHQ1 | SHQ1, H/ACA ribonucleoprotein assembly factor. (638 aa) |
| | ENSCHIP00000009386 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (102 aa) |
| | LOC102176453 | Uncharacterized protein. (291 aa) |
| | ENSCHIP00000009200 | annotation not available (103 aa) |
| | ENSCHIP00000009147 | annotation not available (103 aa) |
| | NOP10 | NOP10 ribonucleoprotein. (64 aa) |
| | TERF1 | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (436 aa) |
| | POLD4 | Uncharacterized protein. (132 aa) |
| | ENSCHIP00000008488 | annotation not available (103 aa) |
| | LOC102188481 | Uncharacterized protein. (379 aa) |
| | LOC102180587 | Histone H2B type 1. (126 aa) |
| | LOC102171353 | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | CENPM | Centromere protein M. (180 aa) |
| | ENSCHIP00000008191 | Histone H2A; Belongs to the histone H2A family. (109 aa) |
| | CENPW | Centromere protein W. (88 aa) |
| | H2BC11 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | RECQL4 | RecQ like helicase 4. (1176 aa) |
| | ENSCHIP00000007586 | H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (198 aa) |
| | H2BC3 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | LOC102185323 | Histone H2B type 1. (126 aa) |
| | LOC106503503 | Histone H4. (103 aa) |
| | CENPI | Centromere protein I. (721 aa) |
| | LOC108636047 | Histone H4. (103 aa) |
| | CENPA | Centromere protein A. (138 aa) |
| | LOC108633916 | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | LOC102171676 | Histone H2A; Belongs to the histone H2A family. (129 aa) |
| | LOC106503502 | Histone H4. (103 aa) |
| | BLM | BLM RecQ like helicase. (1429 aa) |
| | LOC108633924 | Histone domain-containing protein. (138 aa) |
| | LOC108633414 | Histone H2B type 1. (126 aa) |
| | H2BC6 | Histone H2B type 1. (126 aa) |
| | SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1. (1114 aa) |
| | ENSCHIP00000005753 | annotation not available (103 aa) |
| | LOC102180845 | Histone H2B type 1. (126 aa) |
| | LOC102172954 | Histone H4. (103 aa) |
| | POLD2 | DNA polymerase delta 2, accessory subunit. (469 aa) |
| | TEN1 | Uncharacterized protein. (123 aa) |
| | ENSCHIP00000005277 | annotation not available (103 aa) |
| | H2BU1 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | H2BC15 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) |
| | RFC2 | Replication factor C subunit 2. (352 aa) |
| | CHTF18 | Chromosome transmission fidelity factor 18. (948 aa) |
| | MIS18A | MIS18 kinetochore protein A. (232 aa) |
| | H2BC1 | Histone H2B; Belongs to the histone H2B family. (127 aa) |
| | LOC102179187 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | ENSCHIP00000004308 | annotation not available (103 aa) |
| | ENSCHIP00000004265 | Uncharacterized protein. (393 aa) |
| | ENSCHIP00000004224 | Nucleoplasmin domain-containing protein. (252 aa) |
| | ENSCHIP00000004152 | annotation not available (103 aa) |
| | TERT | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1123 aa) |
| | ENSCHIP00000003936 | Histone H2A; Belongs to the histone H2A family. (143 aa) |
| | LOC102172226 | Histone domain-containing protein; Belongs to the histone H2B family. (126 aa) |
| | ENSCHIP00000003593 | Uncharacterized protein. (64 aa) |
| | H2BC18 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | LOC102182181 | Histone H2B type 1. (126 aa) |
| | H2AJ | Histone H2A; Belongs to the histone H2A family. (129 aa) |
| | LOC102183280 | Histone H2B type 1. (126 aa) |
| | LOC108636012 | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | CDK2 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (346 aa) |
| | LOC102175243 | Histone domain-containing protein; Belongs to the histone H2B family. (122 aa) |
| | LOC102182848 | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | LOC102181912 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | ENSCHIP00000002654 | Uncharacterized protein. (121 aa) |
| | H2AC6 | Histone H2A; Belongs to the histone H2A family. (130 aa) |
| | RBBP4-2 | WD_REPEATS_REGION domain-containing protein. (425 aa) |
| | LOC108633554 | Histone domain-containing protein. (136 aa) |
| | ENSCHIP00000001595 | Uncharacterized protein. (333 aa) |
| | LOC102191748 | Histone domain-containing protein. (136 aa) |
| | H2BC12 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | LOC102180307 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
