(25 nodes) Nucleotide salvage network (Capra hircus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Predicted Interactions

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Your Input:
	DGUOK	Deoxyguanosine kinase. (277 aa)
	PRTFDC1	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (225 aa)
	APRT	Adenine phosphoribosyltransferase. (180 aa)
	UPP2	Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (330 aa)
	TK1	Thymidine kinase. (238 aa)
	AMPD1	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (731 aa)
	HPRT1	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
	UCKL1	Uridine-cytidine kinase; Belongs to the uridine kinase family. (552 aa)
	UPP1	Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (312 aa)
	AMPD3	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (786 aa)
	AMPD2	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (817 aa)
	PNP	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa)
	UCK1	Uridine-cytidine kinase; Belongs to the uridine kinase family. (277 aa)
	GMPR2	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (348 aa)
	LOC102176691	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa)
	ADAL	Adenosine deaminase like. (352 aa)
	ADK	Adenosine kinase. (362 aa)
	CDA	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (146 aa)
	ADA	Adenosine deaminase. (400 aa)
	DCK	Deoxycytidine kinase. (260 aa)
	TK2	Thymidine kinase 2. (275 aa)
	GMPR	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (327 aa)
	UCK2	Uridine-cytidine kinase; Belongs to the uridine kinase family. (261 aa)
	ENSCHIP00000026638	Uncharacterized protein. (190 aa)
	PUDP	Pseudouridine 5'-phosphatase. (231 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADA	ADK	ENSCHIP00000033539	ENSCHIP00000000140	Adenosine deaminase.	Adenosine kinase.	0.993
ADA	AMPD1	ENSCHIP00000033539	ENSCHIP00000015272	Adenosine deaminase.	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.	0.628
ADA	AMPD2	ENSCHIP00000033539	ENSCHIP00000010253	Adenosine deaminase.	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.	0.696
ADA	AMPD3	ENSCHIP00000033539	ENSCHIP00000011082	Adenosine deaminase.	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.	0.695
ADA	APRT	ENSCHIP00000033539	ENSCHIP00000019564	Adenosine deaminase.	Adenine phosphoribosyltransferase.	0.866
ADA	CDA	ENSCHIP00000033539	ENSCHIP00000033674	Adenosine deaminase.	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	0.521
ADA	DCK	ENSCHIP00000033539	ENSCHIP00000030481	Adenosine deaminase.	Deoxycytidine kinase.	0.945
ADA	ENSCHIP00000026638	ENSCHIP00000033539	ENSCHIP00000026638	Adenosine deaminase.	Uncharacterized protein.	0.439
ADA	HPRT1	ENSCHIP00000033539	ENSCHIP00000014909	Adenosine deaminase.	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.499
ADA	LOC102176691	ENSCHIP00000033539	ENSCHIP00000006635	Adenosine deaminase.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.988
ADA	PNP	ENSCHIP00000033539	ENSCHIP00000008961	Adenosine deaminase.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.988
ADA	PRTFDC1	ENSCHIP00000033539	ENSCHIP00000020785	Adenosine deaminase.	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.493
ADA	UPP1	ENSCHIP00000033539	ENSCHIP00000013138	Adenosine deaminase.	Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.	0.488
ADA	UPP2	ENSCHIP00000033539	ENSCHIP00000018437	Adenosine deaminase.	Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.	0.407
ADAL	ADK	ENSCHIP00000002208	ENSCHIP00000000140	Adenosine deaminase like.	Adenosine kinase.	0.580
ADAL	APRT	ENSCHIP00000002208	ENSCHIP00000019564	Adenosine deaminase like.	Adenine phosphoribosyltransferase.	0.763
ADAL	ENSCHIP00000026638	ENSCHIP00000002208	ENSCHIP00000026638	Adenosine deaminase like.	Uncharacterized protein.	0.439
ADAL	HPRT1	ENSCHIP00000002208	ENSCHIP00000014909	Adenosine deaminase like.	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.439
ADAL	LOC102176691	ENSCHIP00000002208	ENSCHIP00000006635	Adenosine deaminase like.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.495
ADAL	PNP	ENSCHIP00000002208	ENSCHIP00000008961	Adenosine deaminase like.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.495