(21 nodes) (2008) Hox paralog group 2 genes control the migration of mouse pontine neurons through slit-robo signaling. network (Capra hircus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HOXA2	Homeobox A2. (372 aa)
	BARHL1	BarH like homeobox 1. (327 aa)
	HOXB4	Homeobox B4. (251 aa)
	ROBO2-2	Ig-like domain-containing protein. (128 aa)
	HOXB2	Homeobox B2. (354 aa)
	GLB1L3	Beta-galactosidase. (664 aa)
	CXCL12	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (116 aa)
	SLIT1	Slit guidance ligand 1. (1534 aa)
	ROBO2	Roundabout guidance receptor 2. (1456 aa)
	CXCR4	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (353 aa)
	HOXB3	Homeobox B3. (426 aa)
	HOXA3	Homeobox A3. (437 aa)
	GLB1	Beta-galactosidase. (646 aa)
	PHOX2B	Paired like homeobox 2B. (315 aa)
	HOXB1	Homeobox B1. (302 aa)
	WNT1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
	HOXD4	Homeobox D4. (258 aa)
	NTN1	Netrin 1. (496 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	HOXB5	Homeobox B5. (269 aa)
	PAX6	Paired box 6. (486 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BARHL1	SLIT1	ENSCHIP00000029800	ENSCHIP00000007708	BarH like homeobox 1.	Slit guidance ligand 1.	0.479
CXCL12	CXCR4	ENSCHIP00000007530	ENSCHIP00000011766	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	0.999
CXCL12	GAPDH	ENSCHIP00000007530	ENSCHIP00000025974	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.708
CXCR4	CXCL12	ENSCHIP00000011766	ENSCHIP00000007530	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.	0.999
CXCR4	GAPDH	ENSCHIP00000011766	ENSCHIP00000025974	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.786
CXCR4	PAX6	ENSCHIP00000011766	ENSCHIP00000027464	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	Paired box 6.	0.410
CXCR4	ROBO2	ENSCHIP00000011766	ENSCHIP00000009326	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	Roundabout guidance receptor 2.	0.475
CXCR4	ROBO2-2	ENSCHIP00000011766	ENSCHIP00000030785	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	Ig-like domain-containing protein.	0.475
GAPDH	CXCL12	ENSCHIP00000025974	ENSCHIP00000007530	Glyceraldehyde-3-phosphate dehydrogenase.	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.	0.708
GAPDH	CXCR4	ENSCHIP00000025974	ENSCHIP00000011766	Glyceraldehyde-3-phosphate dehydrogenase.	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	0.786
GAPDH	PAX6	ENSCHIP00000025974	ENSCHIP00000027464	Glyceraldehyde-3-phosphate dehydrogenase.	Paired box 6.	0.745
GAPDH	WNT1	ENSCHIP00000025974	ENSCHIP00000020293	Glyceraldehyde-3-phosphate dehydrogenase.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.687
HOXA2	HOXA3	ENSCHIP00000029207	ENSCHIP00000012412	Homeobox A2.	Homeobox A3.	0.738
HOXA2	HOXB1	ENSCHIP00000029207	ENSCHIP00000018439	Homeobox A2.	Homeobox B1.	0.423
HOXA2	HOXB4	ENSCHIP00000029207	ENSCHIP00000030630	Homeobox A2.	Homeobox B4.	0.419
HOXA2	HOXB5	ENSCHIP00000029207	ENSCHIP00000027045	Homeobox A2.	Homeobox B5.	0.533
HOXA2	ROBO2	ENSCHIP00000029207	ENSCHIP00000009326	Homeobox A2.	Roundabout guidance receptor 2.	0.505
HOXA2	ROBO2-2	ENSCHIP00000029207	ENSCHIP00000030785	Homeobox A2.	Ig-like domain-containing protein.	0.505
HOXA2	WNT1	ENSCHIP00000029207	ENSCHIP00000020293	Homeobox A2.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.460
HOXA3	HOXA2	ENSCHIP00000012412	ENSCHIP00000029207	Homeobox A3.	Homeobox A2.	0.738