STRINGSTRING
BDNF BDNF PVALB PVALB SPR SPR TLR2 TLR2 TH TH NES NES SHH SHH CALM1 CALM1 ALB ALB PAH PAH PXDN PXDN TLR3 TLR3 DBH DBH NTF3 NTF3 QDPR QDPR CALML5 CALML5 NGF NGF CD34 CD34 CALML4 CALML4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (258 aa)
PVALBParvalbumin; Belongs to the parvalbumin family. (111 aa)
SPRSepiapterin reductase. (267 aa)
TLR2Toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequentl [...] (794 aa)
THTyrosine hydroxylase. (516 aa)
NESNestin; Belongs to the intermediate filament family. (1606 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
CALM1Calmodulin 2; Belongs to the calmodulin family. (149 aa)
ALBSerum albumin. (608 aa)
PAHPhenylalanine hydroxylase. (466 aa)
PXDNPeroxidasin. (1525 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (918 aa)
DBHDopamine beta-hydroxylase. (616 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (266 aa)
QDPRQuinoid dihydropteridine reductase. (242 aa)
CALML5Calmodulin like 5. (149 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (241 aa)
CD34Uncharacterized protein. (384 aa)
CALML4Calmodulin like 4. (153 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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