10 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ACTB	Uncharacterized protein. (375 aa)
	RAD51	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
	ERCC1	ERCC excision repair 1, endonuclease non-catalytic subunit. (294 aa)
	MUS81	MUS81 structure-specific endonuclease subunit. (552 aa)
	BRCA2	BRCA2 DNA repair associated. (3405 aa)
	XRCC3	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (341 aa)
	RAD50	Zinc-hook domain-containing protein. (1332 aa)
	XPA	XPA, DNA damage recognition and repair factor. (273 aa)
	REV1	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1254 aa)
	RAD51D	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents; Belongs to the RecA family. RAD51 subfamily. (338 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	BRCA2	ENSCHIP00000011080	ENSCHIP00000024039	Uncharacterized protein.	BRCA2 DNA repair associated.	0.617
ACTB	ERCC1	ENSCHIP00000011080	ENSCHIP00000031141	Uncharacterized protein.	ERCC excision repair 1, endonuclease non-catalytic subunit.	0.460
ACTB	RAD51	ENSCHIP00000011080	ENSCHIP00000033023	Uncharacterized protein.	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.533
BRCA2	ACTB	ENSCHIP00000024039	ENSCHIP00000011080	BRCA2 DNA repair associated.	Uncharacterized protein.	0.617
BRCA2	ERCC1	ENSCHIP00000024039	ENSCHIP00000031141	BRCA2 DNA repair associated.	ERCC excision repair 1, endonuclease non-catalytic subunit.	0.841
BRCA2	MUS81	ENSCHIP00000024039	ENSCHIP00000028466	BRCA2 DNA repair associated.	MUS81 structure-specific endonuclease subunit.	0.915
BRCA2	RAD50	ENSCHIP00000024039	ENSCHIP00000003154	BRCA2 DNA repair associated.	Zinc-hook domain-containing protein.	0.608
BRCA2	RAD51	ENSCHIP00000024039	ENSCHIP00000033023	BRCA2 DNA repair associated.	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.999
BRCA2	RAD51D	ENSCHIP00000024039	ENSCHIP00000021188	BRCA2 DNA repair associated.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents; Belongs to the RecA family. RAD51 subfamily.	0.975
BRCA2	REV1	ENSCHIP00000024039	ENSCHIP00000010141	BRCA2 DNA repair associated.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.520
BRCA2	XPA	ENSCHIP00000024039	ENSCHIP00000006813	BRCA2 DNA repair associated.	XPA, DNA damage recognition and repair factor.	0.602
BRCA2	XRCC3	ENSCHIP00000024039	ENSCHIP00000023459	BRCA2 DNA repair associated.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	0.975
ERCC1	ACTB	ENSCHIP00000031141	ENSCHIP00000011080	ERCC excision repair 1, endonuclease non-catalytic subunit.	Uncharacterized protein.	0.460
ERCC1	BRCA2	ENSCHIP00000031141	ENSCHIP00000024039	ERCC excision repair 1, endonuclease non-catalytic subunit.	BRCA2 DNA repair associated.	0.841
ERCC1	MUS81	ENSCHIP00000031141	ENSCHIP00000028466	ERCC excision repair 1, endonuclease non-catalytic subunit.	MUS81 structure-specific endonuclease subunit.	0.968
ERCC1	RAD50	ENSCHIP00000031141	ENSCHIP00000003154	ERCC excision repair 1, endonuclease non-catalytic subunit.	Zinc-hook domain-containing protein.	0.449
ERCC1	RAD51	ENSCHIP00000031141	ENSCHIP00000033023	ERCC excision repair 1, endonuclease non-catalytic subunit.	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.735
ERCC1	RAD51D	ENSCHIP00000031141	ENSCHIP00000021188	ERCC excision repair 1, endonuclease non-catalytic subunit.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents; Belongs to the RecA family. RAD51 subfamily.	0.488
ERCC1	REV1	ENSCHIP00000031141	ENSCHIP00000010141	ERCC excision repair 1, endonuclease non-catalytic subunit.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.516
ERCC1	XPA	ENSCHIP00000031141	ENSCHIP00000006813	ERCC excision repair 1, endonuclease non-catalytic subunit.	XPA, DNA damage recognition and repair factor.	0.994