35 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ALPL	Alkaline phosphatase. (524 aa)
	FLNA	Filamin A. (2647 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	LOC102179897	Alkaline phosphatase. (530 aa)
	LOC108633351	Uncharacterized protein; Belongs to the alkaline phosphatase family. (531 aa)
	COL5A2	Collagen type V alpha 2 chain. (1252 aa)
	MSN	Moesin. (666 aa)
	ACTB	Uncharacterized protein. (375 aa)
	SCIN	Scinderin. (715 aa)
	CFL2	Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
	FLNB	Filamin B. (2602 aa)
	EZR	Ezrin. (581 aa)
	ALB	Serum albumin. (608 aa)
	RDX	Radixin. (602 aa)
	CNN1	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (297 aa)
	LOC102190919	Alkaline phosphatase. (530 aa)
	COL1A1	Collagen type I alpha 1 chain. (1463 aa)
	GSN	Gelsolin. (785 aa)
	COL4A1	Collagen type IV alpha 1 chain. (1608 aa)
	CNN3	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (329 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
	CNN2	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (309 aa)
	CFL1	Cofilin 1; Belongs to the actin-binding proteins ADF family. (165 aa)
	LOC102190650	Uncharacterized protein; Belongs to the alkaline phosphatase family. (528 aa)
	COL4A2	Collagen type IV alpha 2 chain. (1607 aa)
	LAMB1	Laminin subunit beta 1. (1842 aa)
	LOC102180168	Uncharacterized protein; Belongs to the alkaline phosphatase family. (531 aa)
	COL4A4	Collagen type IV alpha 4 chain. (1434 aa)
	VCL	Vinculin. (1134 aa)
	COL4A6	Collagen IV NC1 domain-containing protein. (170 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (452 aa)
	LOC102190442	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (270 aa)
	LOC102190876	Alkaline phosphatase. (530 aa)
	IQGAP1	IQ motif containing GTPase activating protein 1. (1657 aa)
	LAMA5	Laminin subunit alpha 5. (2263 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	ALB	ENSCHIP00000011080	ENSCHIP00000020234	Uncharacterized protein.	Serum albumin.	0.961
ACTB	ALPL	ENSCHIP00000011080	ENSCHIP00000009165	Uncharacterized protein.	Alkaline phosphatase.	0.408
ACTB	CFL1	ENSCHIP00000011080	ENSCHIP00000029269	Uncharacterized protein.	Cofilin 1; Belongs to the actin-binding proteins ADF family.	0.987
ACTB	CFL2	ENSCHIP00000011080	ENSCHIP00000014949	Uncharacterized protein.	Cofilin 2; Belongs to the actin-binding proteins ADF family.	0.976
ACTB	CNN1	ENSCHIP00000011080	ENSCHIP00000021438	Uncharacterized protein.	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.	0.740
ACTB	CNN2	ENSCHIP00000011080	ENSCHIP00000026998	Uncharacterized protein.	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.	0.706
ACTB	CNN3	ENSCHIP00000011080	ENSCHIP00000025433	Uncharacterized protein.	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.	0.708
ACTB	COL1A1	ENSCHIP00000011080	ENSCHIP00000023918	Uncharacterized protein.	Collagen type I alpha 1 chain.	0.776
ACTB	EZR	ENSCHIP00000011080	ENSCHIP00000018536	Uncharacterized protein.	Ezrin.	0.977
ACTB	FLNA	ENSCHIP00000011080	ENSCHIP00000007945	Uncharacterized protein.	Filamin A.	0.703
ACTB	FLNB	ENSCHIP00000011080	ENSCHIP00000015449	Uncharacterized protein.	Filamin B.	0.538
ACTB	GSN	ENSCHIP00000011080	ENSCHIP00000023939	Uncharacterized protein.	Gelsolin.	0.579
ACTB	IQGAP1	ENSCHIP00000011080	ENSCHIP00000006181	Uncharacterized protein.	IQ motif containing GTPase activating protein 1.	0.961
ACTB	LOC102190442	ENSCHIP00000011080	ENSCHIP00000001133	Uncharacterized protein.	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.	0.706
ACTB	MSN	ENSCHIP00000011080	ENSCHIP00000010531	Uncharacterized protein.	Moesin.	0.958
ACTB	RDX	ENSCHIP00000011080	ENSCHIP00000021221	Uncharacterized protein.	Radixin.	0.953
ACTB	SCIN	ENSCHIP00000011080	ENSCHIP00000012875	Uncharacterized protein.	Scinderin.	0.557
ACTB	TGFB1	ENSCHIP00000011080	ENSCHIP00000008885	Uncharacterized protein.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.831
ACTB	TGFB2	ENSCHIP00000011080	ENSCHIP00000026276	Uncharacterized protein.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.533
ACTB	VCL	ENSCHIP00000011080	ENSCHIP00000000453	Uncharacterized protein.	Vinculin.	0.988