22 items (Capra hircus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	DDHD2	DDHD domain containing 2. (708 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	SLC2A4	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
	IRS2	Insulin receptor substrate 2. (1465 aa)
	ALB	Serum albumin. (608 aa)
	SRC	Tyrosine-protein kinase. (538 aa)
	PSPH	Phosphoserine phosphatase. (225 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (105 aa)
	ACLY	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1101 aa)
	PUM1	Pumilio RNA binding family member 1. (1186 aa)
	PXDN	Peroxidasin. (1525 aa)
	IGF1	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (188 aa)
	PHGDH	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (533 aa)
	LDH-A	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (361 aa)
	FGFR2	Fibroblast growth factor receptor. (841 aa)
	VAMP8	Vesicle associated membrane protein 8. (101 aa)
	TFRC	Transferrin receptor. (790 aa)
	NSD3	Nuclear receptor binding SET domain protein 3. (1447 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1367 aa)
	PSAT1	Phosphoserine aminotransferase. (370 aa)
	INSIG1	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (278 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACLY	GAPDH	ENSCHIP00000027213	ENSCHIP00000025974	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.555
ACLY	INS	ENSCHIP00000027213	ENSCHIP00000007610	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.573
ACLY	INSIG1	ENSCHIP00000027213	ENSCHIP00000027402	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	0.482
ACLY	LDH-A	ENSCHIP00000027213	ENSCHIP00000019303	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.685
ACLY	SLC2A4	ENSCHIP00000027213	ENSCHIP00000022482	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	0.463
ALB	FGFR2	ENSCHIP00000020234	ENSCHIP00000018620	Serum albumin.	Fibroblast growth factor receptor.	0.502
ALB	GAPDH	ENSCHIP00000020234	ENSCHIP00000025974	Serum albumin.	Glyceraldehyde-3-phosphate dehydrogenase.	0.948
ALB	IGF1	ENSCHIP00000020234	ENSCHIP00000020185	Serum albumin.	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	0.793
ALB	IGF1R	ENSCHIP00000020234	ENSCHIP00000028488	Serum albumin.	Tyrosine-protein kinase receptor.	0.629
ALB	INS	ENSCHIP00000020234	ENSCHIP00000007610	Serum albumin.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.973
ALB	IRS2	ENSCHIP00000020234	ENSCHIP00000000977	Serum albumin.	Insulin receptor substrate 2.	0.451
ALB	LDH-A	ENSCHIP00000020234	ENSCHIP00000019303	Serum albumin.	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.817
ALB	MTOR	ENSCHIP00000020234	ENSCHIP00000021872	Serum albumin.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.687
ALB	PXDN	ENSCHIP00000020234	ENSCHIP00000015493	Serum albumin.	Peroxidasin.	0.988
ALB	SLC2A4	ENSCHIP00000020234	ENSCHIP00000022482	Serum albumin.	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	0.722
ALB	SRC	ENSCHIP00000020234	ENSCHIP00000002619	Serum albumin.	Tyrosine-protein kinase.	0.783
ALB	TFRC	ENSCHIP00000020234	ENSCHIP00000033446	Serum albumin.	Transferrin receptor.	0.752
DDHD2	NSD3	ENSCHIP00000008898	ENSCHIP00000031003	DDHD domain containing 2.	Nuclear receptor binding SET domain protein 3.	0.451
FGFR2	ALB	ENSCHIP00000018620	ENSCHIP00000020234	Fibroblast growth factor receptor.	Serum albumin.	0.502
FGFR2	GAPDH	ENSCHIP00000018620	ENSCHIP00000025974	Fibroblast growth factor receptor.	Glyceraldehyde-3-phosphate dehydrogenase.	0.625