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CCDC15 CCDC15 HSPB6 HSPB6 MB MB LOC102183240 LOC102183240 TNF TNF LOC108638252 LOC108638252 PPL PPL ACE ACE ATP5PB ATP5PB IL6 IL6 ATP5ME ATP5ME CRYAB CRYAB NDUFA10 NDUFA10 ATP5F1A ATP5F1A ANP32B ANP32B NDUFV2 NDUFV2 PXDN PXDN ACE2 ACE2 EZR EZR ALB ALB HPCAL1 HPCAL1 HSPA9 HSPA9 NDUFB9 NDUFB9 ATP5MF ATP5MF ATP5PF ATP5PF GAPDH GAPDH DNAJC19 DNAJC19 DMAC2L DMAC2L ATP5F1E ATP5F1E DLD DLD LOC106503207 LOC106503207 ATPAF1 ATPAF1 CHCHD2 CHCHD2 ATP5PD ATP5PD ATPAF2 ATPAF2 HTT HTT ATP5F1D ATP5F1D
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CCDC15Coiled-coil domain containing 15. (780 aa)
HSPB6Heat shock protein family B (small) member 6; Belongs to the small heat shock protein (HSP20) family. (164 aa)
MBMyoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. (154 aa)
LOC102183240ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (547 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa)
LOC108638252ATP synthase subunit; Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proto [...] (103 aa)
PPLPeriplakin. (1755 aa)
ACEAngiotensin-converting enzyme. (1313 aa)
ATP5PBATP synthase peripheral stalk-membrane subunit b. (256 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (237 aa)
ATP5MEUncharacterized protein. (71 aa)
CRYABCrystallin alpha B; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (175 aa)
NDUFA10NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (355 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (560 aa)
ANP32BLRRcap domain-containing protein. (226 aa)
NDUFV2NADH:ubiquinone oxidoreductase core subunit V2. (249 aa)
PXDNPeroxidasin. (1525 aa)
ACE2Angiotensin-converting enzyme. (804 aa)
EZREzrin. (581 aa)
ALBSerum albumin. (608 aa)
HPCAL1Hippocalcin like 1. (193 aa)
HSPA9Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (679 aa)
NDUFB9NADH:ubiquinone oxidoreductase subunit B9; Belongs to the complex I LYR family. (179 aa)
ATP5MFUncharacterized protein. (104 aa)
ATP5PFATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family. (108 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
DNAJC19DnaJ heat shock protein family (Hsp40) member C19. (128 aa)
DMAC2LDistal membrane arm assembly complex 2 like. (200 aa)
ATP5F1EUncharacterized protein. (51 aa)
DLDDihydrolipoyl dehydrogenase. (509 aa)
LOC106503207Angiotensin-converting enzyme. (722 aa)
ATPAF1Uncharacterized protein. (323 aa)
CHCHD2Uncharacterized protein. (152 aa)
ATP5PDATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (162 aa)
ATPAF2ATP synthase mitochondrial F1 complex assembly factor 2. (290 aa)
HTTUncharacterized protein. (2830 aa)
ATP5F1DATP synthase F1 subunit delta. (168 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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