STRINGSTRING
RAD18 RAD18 SUMO1 SUMO1 PIAS3 PIAS3 PIAS2 PIAS2 RTEL1 RTEL1 PIAS4 PIAS4 PIAS1 PIAS1 SUMO4 SUMO4 SAE1 SAE1 PCNA PCNA SUMO3 SUMO3 FBH1 FBH1 SUMO2 SUMO2 RAD51 RAD51
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAD18RAD18 E3 ubiquitin protein ligase. (502 aa)
SUMO1Small ubiquitin-related modifier. (101 aa)
PIAS3Protein inhibitor of activated STAT 3. (628 aa)
PIAS2Uncharacterized protein. (621 aa)
RTEL1Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1212 aa)
PIAS4Protein inhibitor of activated STAT 4. (513 aa)
PIAS1Protein inhibitor of activated STAT 1. (651 aa)
SUMO4Small ubiquitin-related modifier. (95 aa)
SAE1SUMO1 activating enzyme subunit 1. (346 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
SUMO3Small ubiquitin-related modifier. (104 aa)
FBH1F-box DNA helicase 1. (1048 aa)
SUMO2Small ubiquitin-related modifier. (95 aa)
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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