89 items (Capra hircus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NDC80	NDC80 kinetochore complex component. (642 aa)
	CDK1	Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (312 aa)
	KIF18A	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (893 aa)
	KIF23	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (966 aa)
	ZIC1	Zic family member 1. (447 aa)
	TFPI2	Tissue factor pathway inhibitor. (233 aa)
	NRCAM	Neuronal cell adhesion molecule. (1304 aa)
	ITGA2	Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1179 aa)
	WNT4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
	COL15A1	Collagen type XV alpha 1 chain. (1375 aa)
	FMOD	Fibromodulin. (376 aa)
	COL4A2	Collagen type IV alpha 2 chain. (1607 aa)
	ARHGAP11A	Rho-GAP domain-containing protein. (255 aa)
	CADM1	Cell adhesion molecule 1. (461 aa)
	TIRAP	TIR domain containing adaptor protein. (228 aa)
	INHBA	Inhibin beta A subunit. (425 aa)
	LAMB1	Laminin subunit beta 1. (1842 aa)
	PDGFB	Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
	COL4A4	Collagen type IV alpha 4 chain. (1434 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	ITGA11	Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1209 aa)
	CCND2	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (292 aa)
	SPON1	Spondin 1. (807 aa)
	THBS4	Thrombospondin 4. (965 aa)
	ANGPTL4	Angiopoietin like 4. (413 aa)
	KRT18	IF rod domain-containing protein; Belongs to the intermediate filament family. (439 aa)
	LOXL3	Lysyl oxidase like 3. (752 aa)
	CKAP2	Cytoskeleton associated protein 2. (682 aa)
	MMP3	Matrix metallopeptidase 3. (477 aa)
	COL4A1	Collagen type IV alpha 1 chain. (1608 aa)
	LOC102174895	Uncharacterized protein. (735 aa)
	NUF2	NUF2 component of NDC80 kinetochore complex. (465 aa)
	COL1A1	Collagen type I alpha 1 chain. (1463 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	FGF9	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	KRT7	Keratin 7; Belongs to the intermediate filament family. (466 aa)
	RSPO2	R-spondin 2. (243 aa)
	LAMA4	Laminin subunit alpha 4. (1824 aa)
	KIF14	Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1643 aa)
	ITGA4	Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1033 aa)
	EPDR1	Ependymin related 1. (236 aa)
	VCP	Valosin containing protein; Belongs to the AAA ATPase family. (816 aa)
	KIF11	Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1055 aa)
	FBLN1	Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (713 aa)
	DLGAP5	DLG associated protein 5. (843 aa)
	CENPK	Centromere protein K. (271 aa)
	FST	Uncharacterized protein. (344 aa)
	FNDC3A	Fibronectin type III domain containing 3A. (1198 aa)
	PDGFC	Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (397 aa)
	CEP55	Centrosomal protein 55. (468 aa)
	RACK1	Receptor for activated C kinase 1. (317 aa)
	SEMA3A	Semaphorin 3A; Belongs to the semaphorin family. (772 aa)
	GAS2L3	Growth arrest specific 2 like 3. (693 aa)
	COMP	Cartilage oligomeric matrix protein. (757 aa)
	SFRP1	Secreted frizzled related protein 1. (308 aa)
	RSPO3	R-spondin 3. (303 aa)
	MMP16	Matrix metallopeptidase 16. (607 aa)
	TNFAIP6	TNF alpha induced protein 6. (280 aa)
	ACTA1	Uncharacterized protein; Belongs to the actin family. (223 aa)
	MAFB	MAF bZIP transcription factor B. (329 aa)
	ITGA6	Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1072 aa)
	CENPF	Centromere protein F. (3055 aa)
	COL5A2	Collagen type V alpha 2 chain. (1252 aa)
	KIF20B	Kinesin family member 20B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1761 aa)
	NCAPG	Non-SMC condensin I complex subunit G. (1022 aa)
	KLF6	Kruppel-like factor 6. (284 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	DDIT4	DNA damage inducible transcript 4. (229 aa)
	LOC102179881	IF rod domain-containing protein; Belongs to the intermediate filament family. (410 aa)
	CTSK	Cathepsin K; Belongs to the peptidase C1 family. (330 aa)
	ADAM12	ADAM metallopeptidase domain 12. (903 aa)
	KRT16	Keratin 16; Belongs to the intermediate filament family. (445 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (105 aa)
	SGCG	Sarcoglycan gamma. (291 aa)
	ASPM	Abnormal spindle microtubule assembly. (3460 aa)
	TTK	TTK protein kinase. (852 aa)
	DEPDC1	DEP domain containing 1. (812 aa)
	STAT1	Signal transducer and activator of transcription. (834 aa)
	KIF13A	Kinesin family member 13A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1791 aa)
	SFRP4	Secreted frizzled related protein 4. (346 aa)
	MB	Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. (154 aa)
	ADAMTS3	ADAM metallopeptidase with thrombospondin type 1 motif 3. (1202 aa)
	POSTN	Periostin. (836 aa)
	FLRT2	Fibronectin leucine rich transmembrane protein 2. (660 aa)
	FGF11	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (225 aa)
	PDGFD	Platelet derived growth factor D; Belongs to the PDGF/VEGF growth factor family. (370 aa)
	ADAM15	ADAM metallopeptidase domain 15. (866 aa)
	CHI3L1	Chitinase-3-like protein 1; Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling [...] (391 aa)
	SERPINH1	Serpin family H member 1; Belongs to the serpin family. (418 aa)

Your Current Organism:

Capra hircus

NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTA1	COL1A1	ENSCHIP00000010728	ENSCHIP00000023918	Uncharacterized protein; Belongs to the actin family.	Collagen type I alpha 1 chain.	0.472
ADAM12	ITGA11	ENSCHIP00000008349	ENSCHIP00000030685	ADAM metallopeptidase domain 12.	Integrin subunit alpha 11; Belongs to the integrin alpha chain family.	0.608
ADAM15	MMP16	ENSCHIP00000002553	ENSCHIP00000010990	ADAM metallopeptidase domain 15.	Matrix metallopeptidase 16.	0.410
ADAMTS3	COL5A2	ENSCHIP00000004252	ENSCHIP00000009695	ADAM metallopeptidase with thrombospondin type 1 motif 3.	Collagen type V alpha 2 chain.	0.415
ANGPTL4	INS	ENSCHIP00000027935	ENSCHIP00000007610	Angiopoietin like 4.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.483
ANGPTL4	PDGFC	ENSCHIP00000027935	ENSCHIP00000015270	Angiopoietin like 4.	Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family.	0.466
ANGPTL4	TGFB1	ENSCHIP00000027935	ENSCHIP00000008885	Angiopoietin like 4.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.503
ARHGAP11A	ASPM	ENSCHIP00000031963	ENSCHIP00000006484	Rho-GAP domain-containing protein.	Abnormal spindle microtubule assembly.	0.820
ARHGAP11A	CENPF	ENSCHIP00000031963	ENSCHIP00000009702	Rho-GAP domain-containing protein.	Centromere protein F.	0.822
ARHGAP11A	CEP55	ENSCHIP00000031963	ENSCHIP00000014965	Rho-GAP domain-containing protein.	Centrosomal protein 55.	0.788
ARHGAP11A	DEPDC1	ENSCHIP00000031963	ENSCHIP00000006096	Rho-GAP domain-containing protein.	DEP domain containing 1.	0.546
ARHGAP11A	DLGAP5	ENSCHIP00000031963	ENSCHIP00000018125	Rho-GAP domain-containing protein.	DLG associated protein 5.	0.807
ARHGAP11A	KIF11	ENSCHIP00000031963	ENSCHIP00000019146	Rho-GAP domain-containing protein.	Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.853
ARHGAP11A	KIF18A	ENSCHIP00000031963	ENSCHIP00000001371	Rho-GAP domain-containing protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.638
ARHGAP11A	KIF23	ENSCHIP00000031963	ENSCHIP00000001286	Rho-GAP domain-containing protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.543
ARHGAP11A	NCAPG	ENSCHIP00000031963	ENSCHIP00000009518	Rho-GAP domain-containing protein.	Non-SMC condensin I complex subunit G.	0.452
ARHGAP11A	NDC80	ENSCHIP00000031963	ENSCHIP00000000515	Rho-GAP domain-containing protein.	NDC80 kinetochore complex component.	0.795
ARHGAP11A	NUF2	ENSCHIP00000031963	ENSCHIP00000024616	Rho-GAP domain-containing protein.	NUF2 component of NDC80 kinetochore complex.	0.637
ARHGAP11A	TTK	ENSCHIP00000031963	ENSCHIP00000006228	Rho-GAP domain-containing protein.	TTK protein kinase.	0.817
ASPM	ARHGAP11A	ENSCHIP00000006484	ENSCHIP00000031963	Abnormal spindle microtubule assembly.	Rho-GAP domain-containing protein.	0.820