STRINGSTRING
SNAP23 SNAP23 STX4 STX4 LAMP2 LAMP2 IL6 IL6 CD81 CD81 FYN FYN CD63 CD63 CD9 CD9 TNF TNF LOC108636029 LOC108636029 SRC SRC CTSD CTSD LAMP1 LAMP1 HEXB HEXB HEXA HEXA IL4 IL4 ALB ALB LOC102190507 LOC102190507 VAMP8 VAMP8 PXDN PXDN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (208 aa)
STX4Syntaxin 4; Belongs to the syntaxin family. (296 aa)
LAMP2Lysosomal associated membrane protein 2. (494 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (237 aa)
CD81Tetraspanin. (236 aa)
FYNTyrosine-protein kinase. (537 aa)
CD63Tetraspanin. (237 aa)
CD9Tetraspanin. (226 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa)
LOC108636029Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa)
SRCTyrosine-protein kinase. (538 aa)
CTSDPeptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (412 aa)
LAMP1Lysosomal associated membrane protein 1. (409 aa)
HEXBBeta-hexosaminidase. (540 aa)
HEXABeta-hexosaminidase. (529 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (135 aa)
ALBSerum albumin. (608 aa)
LOC102190507Uncharacterized protein. (139 aa)
VAMP8Vesicle associated membrane protein 8. (101 aa)
PXDNPeroxidasin. (1525 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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